Sentences with phrase «identify epigenetic changes»

The team ultimately seeks to identify epigenetic changes for better understanding of why certain patients respond to treatment compared to non-responders.

As we improve methods to identify epigenetic changes that occur during tumor development, can we develop approaches to discriminate between «driver» and «passenger» epigenetic events?

To identify these epigenetic changes, they examined whether genes had methyl groups attached to them.

Bale's group will next try to identify epigenetic changes in embryos that might allow miRNA changes to have an effect in adult animals.

Not exact matches

«At this time, when prescription opioid use and opioid overdoses are both major threats to our public health, it is important to identify new treatment targets, such as epigenetic processes, that help to change the way that we do business in treating opioid use disorders,» said professor John Krystal, Editor of Biological Psychiatry.

And because epigenetic changes typically occur early in life, it may one day be possible to identify young people at risk for suicide by studying their methylation patterns and then to treat them with drugs that regulate this mechanism, Szyf notes.

They identified 24 previously unknown epigenetic changes that alter a woman's risk of breast cancer and can be passed down through generations without involving changes in the DNA sequence of genes.

It's the first time anyone has identified changes in these chemical tags — known as epigenetic changes — in the sperm of obese men, he says.

For example, the discovery of cancer - causing genetic and epigenetic changes in tumors has enabled the development of therapies that target these changes as well as diagnostic tests that identify patients who may benefit from these therapies.

Some studies have identified a number of regions of methylated DNA (one key way in which epigenetic changes occur) that are different in fat cells of mice fed high - fat diets than in cells of mice with normal diets.

I study genetic and epigenetic changes induced by smoking and other environmental factors to identify the mechanisms that play a role in carcinogenesis.