Sentences with phrase «identify epigenetic factors»
The current study was designed to clarify the cellular hierarchy underlying glioblastoma, to identify epigenetic factors that distinguish glioblastoma stem cells from more differentiated tumor cells and to suggest potential therapies targeting those factors.
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Recent studies have expanded the search for genetic links from identifying genes toward epigenetics, the study of factors that control gene expression and looks at chemical modifications of DNA and the proteins associated with it.
Ladd - Acosta's research is focused on integrating genome - wide genotyping, genome - scale epigenetic and prenatal environmental exposure data, at a population level, to understand how these factors influence autism risk and to identify biologic pathways that could serve as molecular targets for prevention and intervention efforts.
Researchers have identified a host of factors involved in epigenetic control of gene expression and development, but many of the precise mechanisms underlying this type of regulation remain unclear.
The study is the most comprehensive effort yet to identify and understand genetic and epigenetic factors that work together to cause ALL, the most common childhood cancer.
Measurements that are increasingly available range from those that identify transcription factor occupancy and initiation of transcription to long - lasting and heritable epigenetic marks such as DNA methylation.
I study genetic and epigenetic changes induced by smoking and other environmental factors to identify the mechanisms that play a role in carcinogenesis.