Sentences with phrase «identify gene alterations»

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«Gene mutations behind lack of a nose identified: Alterations in same gene previously associated with rare form of muscular dystrophy.&raGene mutations behind lack of a nose identified: Alterations in same gene previously associated with rare form of muscular dystrophy.&ragene previously associated with rare form of muscular dystrophy.»

«Some of these genes were either increased or decreased in the area of the tumour, no matter the type of breast cancer, and this is important because within the patterns we identified were predictable alterations.

This observation is further supported by the fact that studying alterations in the expression of genes also made it possible to identify persons whose levels of interleukin 6, an inflammation marker, were reduced as their serum vitamin D levels increased.

Some of the common genetic alterations identified in the study were gains and losses in chromosome 8, as well as cell proliferation and cell - cycle progression — key mechanisms of cancer caused by genetic alterations — linked to the genes AURKA, AURKB and FOXM1.

They uncovered more than 2,500 alterations, and identified 10 significantly mutated genes.

They also identified SNPs (single nucleotide polymorphisms, or alterations to the genetic code created by the addition or deletion of a single nucleotide in a gene's long chain).

Utilizing the invasive breast cancer data set of 962 cases in The Cancer Genome Atlas, all breast cancers with alterations in the CDH1 gene (that gives instructions to make a protein that causes cancer cells to stick to one another and defines lobular breast cancers) were identified.

Though some of the affected genes have been identified, the physical manifestations of these alterations remain largely uncharacterized.

In a collaborative study, researchers from Chinese Academy of Medical Sciences and Peking Union Medical College, BGI, Shantou University Medical College and other institutions identified important alterations of tumor - associated genes and tumorigenic pathways in esophageal squamous cell cancer (ESCC), one of the leading cause of cancer death worldwide.

This will be achieved by exposing the coral to seawater with high calcium concentrations to induce an alteration in gene expression profiles, identified using a DNA microarray analysis.

The investigators also identified alteration in NTRK genes that drove tumor development in young HGG patients whose tumors developed outside the brainstem.

The scientific goal of the Cancer Biology Program is to identify novel genomic and genetic alterations that play causal roles in cancer development and to study genes, proteins, and signaling pathways that mediate the altered phenotypes of cancer cells.

The study is considered proof - of - principle that gene sequencing to identify cancer - related alterations may be a helpful tool in detecting cancer DNA directly in the blood and potentially other body fluids.

To identify additional alterations, the investigators looked at DNA copy number changes, or changes in gene number resulting from the deletion or amplification (multiplication) of sections of DNA in the genome.

Under this law, «genetic testing» is defined as follows: «a test, examination, or analysis which is generally accepted in the scientific and medical communities for the purpose of identifying the presence, absence, or alteration of any gene or chromosome, and any report, interpretation, or evaluation of such a test, examination, or analysis, but excludes any otherwise lawful test, examination, or analysis that is undertaken for the purpose of determining whether an individual meets reasonable functional standards for a specific job or task.»