Sentences with phrase «identify genes of interest»

These findings are a proof of concept of novel methods to functionally annotate genomes in order to more quickly identify genes of interest.

Using genetic modification in this way can improve the accuracy of identifying genes of interest and speed up the breeding process, even though the end - product is not GM rice.

Not exact matches

To gain more insights as to why zebrafish are more successful at regenerating spinal tissue, the researchers analyzed the gene expression of fish spinal tissue following injury, identifying seven genes of interest.

Genomics - based discovery is key for identifying genes of potential interest to plant breeders and biotech seed developers.

«Our team studied thousands of molecular clues in each of these samples, sifting through extensive data on the activity of genes, proteins and other molecules to identify those of most interest,» says Katrina Waters, a biologist at PNNL and a corresponding author of the study.

«Our team studied thousands of molecular clues in each of these samples, sifting through extensive data on the activity of genes, proteins, and other molecules to identify those of most interest,» said Katrina Waters, the leader of the PNNL team and a corresponding author of the paper.

This under - expression was particularly interesting because although hundreds of genes have already been identified for their presumed roles in autistic disorders, each one alone can at best only explain 1 % of cases.

A year ago we started thinking, why don't we select a single family with an interesting disease and see whether studying a smaller group of related individuals makes it possible to identify the genes involved in that disease.

The Finnish researchers had used a set of «gene wrenches» called RNAi molecules, to turn off genes of interest, and with these additional experiments the researchers identified tracks leading to a nuclear protein and gene controller protein called SRF.

A second project, dubbed Eumorphia, will organize more than a dozen labs in nine countries to systematically screen new mouse mutants for interesting characteristics — a key step in determining the function of newly identified genes.

Thus µSCALE empties the contents of a single capillary onto a collector plate, where the DNA of the isolated cell can be sequenced and the gene variant responsible for the protein of interest can be identified.

«We have deposited all the data and the toolkit in a public platform, which will help researchers identify and validate the functions of their genes of interest,» says Auwerx, placing the project within the context of EPFL's ongoing efforts to advance open science.

A well - defined cell type that has been widely used to identify the consequences of ablation or ectopic expression of a gene of interest.

The United Kingdom - based group, led by Julie Williams, Ph.D., Cardiff University School of Medicine, Wales, found the same genes as risk factors and identified a gene variant ABCA7 as an additional gene of interest.

Botstein and Davis» landmark conceptual breakthrough, published in 1980, gave researchers the tools to trace and map out the genetic inheritance of disease in humans, while Hogness» work provided the means of identifying the precise physical location of genes of interest on chromosomes.

By comparing the whole genome sequence of the lab - cultured resistant strain with a sibling strain that had not been exposed to the drug, they were able to identify several mutations of interest in a number of genes.

He is also interested in genes induced by the interferon response, and his future plans include investigating genes identified in the expression of genome - wide association screens for predisposition to cancers.

Restricting these differentially expressed genes to ones that changed by at least 4-fold in any comparison, at a stringent p - value cutoff of P < 0.0001, we identified three groups of biologically interesting genes.

His research team is interested in identifying genes that direct the development of the cerebral cortex, both because of their importance in human diseases and because studying those genes will help in learning about the normal development and evolution of the brain.

The Bioinformatics group uses computational methods to analyse genome sequences, amino acid sequences, and gene expression data, both to identify new genes of interest and to determine their structure, function and role in the cell.

However, if the purpose of such a scan is to identify candidate genes, then — as with single - gene studies — more detailed follow - up and functional validation of at least some of the key genes of interest are necessary to shore up the evidence.

Homozygosity mapping of 5 cases (4 full - sibs, 1 half - sib) and 5 controls (2 parents, 3 full - sibs) via Illumina CanineHD SNP genotyping BeadChips identified a single chromosome (canine chromosome 36; CFA36) of interest where the gene containing a responsible mutation is expected to be located.

Genetic testing — which the report describes as «the analysis of a person's chromosomes, genes, or gene products (proteins) to identify the presence of specific traits» — is accessible to Canadians interested in learning more about their predisposition to certain health issues, or for diagnosis.