Sentences with phrase «identify human genome sequences»

In the current study, Chaput designed an in vitro selection strategy to identify human genome sequences that initiate cap - independent translation.

Not exact matches

An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers — sequences of DNA that act to amplify the expression of a specific gene — in the genomes of humans and other mammals.

Using metabolic function analyses of identified genes, we compared our human genome with the average content of previously sequenced microbial genomes.

In - depth analysis of the human body's microflora has been possible only in the past few years — a by - product of the same new gene sequencing techniques that have allowed scientists to cheaply and accurately identify the DNA of the human genome.

Just as the Human Genome Initiative in the 1990s sequenced human DNA for the subsequent identification and analysis of genes, so too will the Materials Genome Initiative sequence materials for identifying new properties for a variety of applicatHuman Genome Initiative in the 1990s sequenced human DNA for the subsequent identification and analysis of genes, so too will the Materials Genome Initiative sequence materials for identifying new properties for a variety of applicathuman DNA for the subsequent identification and analysis of genes, so too will the Materials Genome Initiative sequence materials for identifying new properties for a variety of applications.

The research team from the National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), both parts of NIH, extended their recent genome sequencing study of skin bacteria, using DNA sequencing techniques optimized for identifying Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), both parts of NIH, extended their recent genome sequencing study of skin bacteria, using DNA sequencing techniques optimized for identifying genome sequencing study of skin bacteria, using DNA sequencing techniques optimized for identifying fungi.

The advent of large - scale genome sequencing has helped scientists identify DNA bacteriophages in the human gut, skin and blood as well as in the environment, but few researchers have looked for RNA bacteriophages in those samples.

When researchers decided to sequence the human genome in the late 1990s, they were focused on finding those traditional genes so as to identify all the proteins necessary for life.

Using whole exome sequencing (a next generation test to analyze the exons or coding regions of thousands of genes simultaneously) conducted at the Baylor College of Medicine Human Genome Sequencing Center, the researchers identified CLP1 mutations in two unrelated families with thesequencing (a next generation test to analyze the exons or coding regions of thousands of genes simultaneously) conducted at the Baylor College of Medicine Human Genome Sequencing Center, the researchers identified CLP1 mutations in two unrelated families with theSequencing Center, the researchers identified CLP1 mutations in two unrelated families with the disorder.

In particular, the Neandertal genome sequence can now be used to catalog changes that have become «fixed» (are invariant within a population or species) in modern humans during the last few hundred thousand years and should be helpful for identifying genes affected by positive selection since humans diverged from Neandertals.

Ending a long - standing mystery that once set the unidentified flying object community abuzz, researchers have sequenced the entire genome of a strange, 15 - centimeter - tall human skeleton and identified mutations that may be responsible for its odd appearance.

Using the new approach in the hydatidiform genome, the researchers were able to identify and sequence 26,079 segments that were different from a standard human reference genome used in genome research.

In these experiments, Berger and colleagues show that somatic PREX2 mutations identified through whole - genome sequencing of human melanoma can contribute to enhanced lethality of tumor xenografts in nude mice (Figure 3B, S6B, and S6C; Berger et al., 2012).

Each of the working groups is responsible for developing a proposal for a set of genomes to sequence that would advance knowledge in one of three important scientific areas: identifying areas in genetic research where the application of high - throughput sequencing resources would rapidly lead to significant medical advances; understanding of the human genome; and understanding the evolutionary biology of genomes.

The National Human Genome Research Institute, part of the National Institutes of Health, has awarded $ 9.1 million over four years to a research team led by the University of Chicago to identify all regulatory elements, the DNA sequences that control when and where specific genes get turned on or off, in the fruit fly gGenome Research Institute, part of the National Institutes of Health, has awarded $ 9.1 million over four years to a research team led by the University of Chicago to identify all regulatory elements, the DNA sequences that control when and where specific genes get turned on or off, in the fruit fly genomegenome.

The Cancer Genome Project at the Wellcome Trust Sanger Institute is part of an international project using DNA sequencing to identify mutations in genes critical to the development of human cancers.

In 1990, scientists set out to identify and sequence these genes in what has famously become known as the Human Genome Project.

The National Institute on Aging (NIA) and the National Human Genome Research Institute (NHGRI) were asked to develop and execute a large scale sequencing project to identify AD risk and protective gene variants.

Knowing the sequence of the human genome means that potent therapeutic siRNA molecules can be identified quickly, ready to be tested in the relevant models.

To reconstruct modern human evolutionary history and identify loci that have shaped hunter - gatherer adaptation, we sequenced the whole genomes of five individuals in each of three different hunter - gatherer populations at > 60 × coverage: Pygmies from Cameroon and Khoesan - speaking Hadza and Sandawe from Tanzania.

For the Standard Sequencing Service, all of these variation types are identified in comparison to the human genome reference.

His research group provided the first genome - wide view of segmental duplications within human and other primate genomes and he is a leader in an effort to identify and sequence normal and disease - causing structural variation in the human genome.

The Broad Institute and its collaborating institutions have received two major grants from the National Human Genome Research Institute (NHGRI) that will support the use of genome sequencing and analysis to identify the genes and genetic variation that underlie both rare and common disGenome Research Institute (NHGRI) that will support the use of genome sequencing and analysis to identify the genes and genetic variation that underlie both rare and common disgenome sequencing and analysis to identify the genes and genetic variation that underlie both rare and common diseases.

By analyzing genome sequence data from human populations, including 1269 individuals from sub-Saharan Africa, we identify a diverse array of large copy number variants affecting the host invasion receptor genes GYPA and GYPB We find that a nearby association with severe malaria is explained by a complex structural rearrangement involving the loss of GYPB and gain of two GYPB - A hybrid genes, which encode a serologically distinct blood group antigen known as Dantu.

ENCODE was launched in 2003 to identify and characterize the functional elements in the human genome sequence.

In addition, recent genome - wide association studies have identified several hundred common genetic variants — inherited changes in the DNA sequence of the human genome — that play a role in an individual's susceptibility to complex human illnesses such as heart disease, mental illnesses, cancer and diabetes.

As of September 1998, we have identified the map positions of bacterial clones covering approximately 860 Mb for sequencing and completed > 98 Mb (approximately 3.3 %) of the human genome sequence.

«The availability of the human genome sequence allows scientists to scan sequences to identify kinases, and the increased speed with which DNA can be sequenced enables us to rapidly search for mutations in those kinases in human cancers,» said Markowitz.

Researchers sequencing the canine genome have identified around 19,000 dog genes compared to the 25,000 or more genes in the human genome.