With the emergence of Ebola virus from
bats and hantaviruses from rodents, investigators say
identifying the other species
infected with HAV provides novel insight into the evolution of HAV and how it spread to humans, and highlights the utility of analyzing animal reservoirs for risk assessment of emerging viruses.
(i) Direct smears from
bat snouts, Periodic Acid Schiff - stained tissue sections from
infected tissues, and scanning electron micrographs of
bat tissues all showed fungal structures similar to those of G. destructans (ii) G. destructans DNA was directly amplified from
infected bat tissues (iii) Isolations of G. destructans in cultures from
infected bat tissues showed 100 % DNA match with the fungus present in positive tissue samples (iv) RAPD patterns for all G. destructans cultures isolated from two sites were indistinguishable (v) The fungal isolates showed psychrophilic growth (vi) We
identified in vitro proteolytic activities suggestive of known fungal pathogenic traits in G. destructans.