Any experimental approach to
identify markers for a disease gene requires samples for the isolation of the genetic material from both affected and unaffected dogs.
In 2016, Dmitry I. Gabrilovich, M.D., Ph.D., program leader of Wistar's Translational Tumor Immunology program, and his research team
identified a marker for myeloid - derived suppressor cells (MDSCs), a population of immune cells implicated in tumor resistance to various types of cancer treatment, including targeted therapies, chemotherapy and immunotherapy.
Not exact matches
To make sense of this, it's important
for designers of those solutions to know how to take human interactions (emails, chats, phone calls, social media threads) and tag them, by
identifying emotion and sentiment, and other
markers so the computer «understands» humans better.
The new research has the potential to be used by the bakery sector to allow
for more accurate testing
for the presence of these
marker proteins, thereby
identifying so - called «hidden allergens».
Multiple genetic
markers have been
identified for celiac disease, but many genetically susceptible individuals tolerate gluten and never develop symptoms, leading to speculation about other risk factors, including early childhood nutrition.
These colorful wooden spoon plant
markers will help you
identify the plants in your garden and get you ready
for the riot of color that your fruits and vegetables will bring!
«Our data need to be replicated, but it is our hope that the oxytocin receptor
marker we have
identified will be useful to clinicians in
identifying women at risk
for postpartum depression,» said first author Dr Aleeca Bell of the University of Illinois, Chicago.
The meat of the book is great in that it
identifies some great
markers of success
for children.
To
identify position - taking, listen
for phrases that are
markers of time - «today», «tonight», «as we speak», «five years ago», «I remember when» - or
markers of place like «Britain» or «our country».
They
identified 11 gene changes that could be biological
markers for spotting people who might be considering suicide (see «Changing of the genes «-RRB-, and they monitored these same
markers in a test group of 265 men with psychiatric conditions.
Individuals were classified as high risk
for Alzheimer's if a DNA test
identified the presence of a genetic
marker — having one or both of the apolipoprotein E-epsilon 4 allele (APOE - e4 allele) on chromosome 19 — which increases the risk of developing the disease.
In early 2000 they decided to fund a project to develop methods to first prioritise those species at greatest risk, and then to
identify those where DNA
markers (characterised differences in DNA used
for identity) were not currently available, but could be of potential use in enforcement cases.
«
Markers for prostate cancer death can
identify men in need of more aggressive treatment.»
Despite this, the extensive breadth of the new study allowed the researchers to
identify several genetic
markers underlying the fruit size increases, which is great news
for breeders who might want to further increase the apple's girth.
Species
for which we still could not
identify markers were examined further by performing general Internet searches and looking at the Web sites of wildlife forensics labs and other relevant organisations.
The next stage involved feeding those species
for which no
markers could be
identified into a more comprehensive database of published literature, which was available to LGC on a pay - per - go basis.
«This provides breeders with a perfect genetic
marker for identifying semideterminancy in soybean seeds and seedlings,» he said.
The
marker of antigens produced by pancreatic cancer has a low positive predictive value
for identifying early stage disease.
«Researchers
identify genetic
marker for heart failure.»
«We hope that our work will provide the basis
for a larger study of patient samples that may ultimately
identify biomarkers that can be used as surrogate
markers to determine the benefit of therapeutic interventions in diagnosed but asymptomatic HD patients to prevent or delay disease onset.»
Mental illness, he adds, has too long been regarded as simply mental: «
Identifying the biological
markers and risk
for mental illness in early childhood may ultimately have a huge impact on human and economic health.
The new method
for replicating genetic
markers, SNPs via MPS, were found to be successful in
identifying the ancestry of a suspect in most tests in the laboratory, which can provide another avenue
for testing degraded DNA samples.
«We need a constellation of genes, including those
for strain
markers and toxins, that could be used to
identify dangerous bacteria,» says Glenn Morris, director of the Emerging Pathogens Institute at the University of Florida in Gainesville.
«This opens a new door in
identifying biological
markers for dementia since we might consider using the brain's processing of speech sounds as a new way to detect the disease earlier,» says Dr. Claude Alain, the study's senior author and senior scientist at Baycrest's Rotman Research Institute (RRI) and professor at the University of Toronto's psychology department.
On the scientific agenda are
identifying molecular
markers for resistance, which would simplify testing; accelerating the development of alternative drugs; and studying the effectiveness of mass screening and treatment to eliminate malaria in the areas where resistance occurs.
This is the first study to
identify histone crotonylation as a driver
for HIV transcription and de-crotonylation of histone as an epigenetic
marker for HIV silencing.»
Building on previous animal and human research, the study
identifies an electrophysiological
marker for threat in the brain.
The team focused on sections of DNA that they suspected would provide
markers for past population movements and
identified nearly 400,000 DNA positions across the genome in each individual.
Instead, she advocates
for well - trained police officers who can
identify the behavioral signs of impairment and less invasive biological
marker tests, which could be immediately performed at the roadside to confirm the presence of a cannabinoid.
«New cancer
marker identified; possible therapeutic target
for breast cancer.»
One of the challenges has been to
identify specific
markers for metastatic BLBC, which would allow development of drugs and prediction of survival.
«The
markers we
identified can be used to develop a biomarker panel
for pre-symptomatic testing even among people who did not have a family history,» Iyengar indicated.
«After the IPN
markers were
identified in 2007,» continues Dr Santi, «we have been working
for seven years on mapping the mechanism
for resistance to the IPN virus.
A new study indicates that, at least
for most major groups in the United States, self -
identified ethnicity corresponds closely with what genetic
markers reveal, suggesting that race can be a useful guide to at least some aspects of biology.
When the scientists looked
for the human version of the newly
identified fly
marker for sleep deprivation, they found ITGA5 and realized it hadn't been among the human immune genes they screened at the start of the study.
«Investigating these pathways may
identify other targets
for therapy or other
markers that predict treatment response,» says first author Theresa Wampler Muskardin, M.D., a rheumatologist at Mayo Clinic in Rochester, Minn. «It will help rheumatologists find the right drug
for each patient and spare patients medications that won't work
for them.»
For instance, company researchers have recently identified a promising new genetic marker for a particular cancer; because Avalon already has all the patents filed on the discovery, Carter and the management team recently gave the scientists the go - ahead to write up two papers on the wo
For instance, company researchers have recently
identified a promising new genetic
marker for a particular cancer; because Avalon already has all the patents filed on the discovery, Carter and the management team recently gave the scientists the go - ahead to write up two papers on the wo
for a particular cancer; because Avalon already has all the patents filed on the discovery, Carter and the management team recently gave the scientists the go - ahead to write up two papers on the work.
Next steps
for the team include
identifying microbiota metabolites whose levels are either significantly elevated or depleted during diseases such as IBD or cancer, to find disease - specific
markers and explore possible roles
for these metabolites in disease progression.
Researchers at Karolinska Institutet have
identified cell surface
markers specific
for the very earliest stem cells in the human embryo.
Scientists at The Institute of Cancer Research (ICR) used the cells of fruit flies, modified with a fluorescent
marker that is activated when the cells are put under stress, to
identify the signals responsible
for driving up activity of the ER.
Similar experiments could
identify new
markers of diseased tissue or new targets
for targeted molecular therapies.
Our team proposes using the strains containing all the
identified evolutionary
markers as vaccine candidates
for upcoming influenza seasons,» Kainov continues.
Researchers at the Ludwig - Maximilians - University, the German Center
for Neurodegenerative Diseases (DZNE), and the Institute
for Stroke and Dementia Research (ISD) in Munich, Germany, have
identified a brain inflammation
marker in patients at early asymptomatic stages of Alzheimer's disease.
Identifying genetic
markers might help accelerate selective breeding
for resistance.
A newly published International Osteoporosis Foundation (IOF) and European Calcified Tissue Society (ECTS) Working Group position paper [1] proposes measuring specific bone turnover
markers (BTMs) in patients who have initiated use of oral bisphosphonates
for postmenopausal osteoporosis as a clinically feasible and practical way to
identify low adherence.
By studying video footage of children interacting with a psychiatrist, computer - vision algorithms learn to
identify behavioural
markers as designated on the Autism Observation Scale
for Infants.
Most simply, once these genes, or bits of DNA tied to the genes (known as
markers), have been
identified, molecular breeders can quickly target offspring inheriting the genes
for further development, cutting breeding time and improving the crop's «genetic gain,» the generational improvements made to a crop, like increased height, by human selection.
For the first time, researchers report
identifying a biological
marker: the over-production of specific genes that could be a diagnostic indicator of mental illness in female psychiatric patients.
The researchers believe that they have
identified a group of RNA molecules — known as long noncoding RNAs (lncRNAs)-- that hold the potential
for serving as better prognostic
markers for prostate cancer.
«The detection of
markers associated with autism early in life, before a child can be diagnosed with autism, is important to help
identify children at the greatest need
for early interventions.»