From this conceptual and empirical review, it is concluded that an overemphasis on clinical outcomes carries unnecessary risks (e.g., weak causal reasoning and a failure to
identify mechanisms of change), while underemphasizing the several benefits of a more inclusive approach (e.g., increasing outcome research and improving supervision).
Not exact matches
Beyond this general problem, Bellah, Habermas, and Luhmann seldom
identify the
mechanisms of cultural
change.
That
change was based on an in - depth study
of the tackle, done to
identify the
mechanisms for head injury.
The study is correlational and can't
identify the
mechanism underlying this relationship, but one can imagine that it «could be that beliefs about the role
of women in science
change as more women enter science, that more women enter science when these beliefs
change, or a combination.
According to the research team, the failure
of these types
of outcomes monitoring systems to produce measurable improvements in outcomes may be related to difficulties in
identifying mechanisms that translate reports into
changes in how surgical care is provided.
It complements previous research that already linked such phenomena to climate
change, but did not yet
identify a
mechanism behind it,» says Hans Joachim Schellnhuber, director
of PIK and co-author
of the study.
Project leader Enno Schefuß from the MARUM — Center for Marine Environmental Sciences at the University
of Bremen, Germany, adds: «The project was funded by the Deutsche Forschungsgemeinschaft in the priority programme «Integrated Analysis
of Interglacial Climate Dynamics (INTERDYNAMIC)» with the aim to
identify potential
mechanisms triggering abrupt
changes under current climatic conditions.
«We've been able to
identify some
of the genetic
mechanisms for the
changes we see,» Rosenblum says.
Furthermore, clipping or genetically ablating wings from flies prevented the protective effects
of DR on lifespan, demonstrating a critical role for the observed increase in physical activity in determining lifespan upon DR. To further elucidate the
mechanisms by which
changes in DR mediates
changes in metabolism we are
identifying and characterizing various tissue specific modulators
of fat metabolsm
Additional limitations to the traditional approach include: costly failures to replicate positive results in larger trials; difficulty in determining the reasons for negative results; low yield in terms
of identifying disease or intervention
mechanisms due to an exclusive focus on symptom
change and clinical endpoints; and, the expensive and very lengthy practice
of first establishing multi-component psychosocial treatments followed by years
of «unpacking» studies.
The next challenge for the team is to
identify what might be some
of the
mechanisms at the molecular level driving these
changes.
In new research published in the journal Nature Climate
Change, an international scientific team has
identified a powerful internal
mechanism that could enable some corals and their symbiotic algae to counter the adverse impact
of a more acidic ocean.
Therefore the group studies with sophisticated imaging technology in vitro and ex vivo: i) the molecular
mechanism driving the migration
of HIV through the intestinal epithelial barrier; ii) the cellular targets in the mucosa, in specific macrophages and DCs, to
identify the possible pathways to invade the tissue and disseminate to other organs; iii) the involvement
of DCs and their functional properties in mediating adaptive immune responses at mucosal level; and iv) the role
of antibodies with different effector functions in
changing the pathways
of the virus.
My studies
of cancer genomes have led to characterization
of multiple pediatric and adult tumor types, to development
of methods that
identify and characterize
changes in genomic heterogeneity, to defining acquired resistance
mechanisms to targeted therapies and to designing novel, personalized vaccines for individual patients.
Free radical damage caused by electron - seeking, highly reactive, oxidative molecules has been
identified as the source
of many maladies through
mechanisms such as inhibition
of telomerase,
changes to cellular permeability and DNA damage.
Antibiotics have been
identified as a potential risk factor for the development
of celiac disease, and the proposed
mechanism relates to
changes in the microbiome exacted by these medications.
Scientists have
identified multiple
mechanisms by which green tea extract helps protect against LDL oxidation, neuronal degradation, and a host
of other structural and functional age - related
changes.
Its strategy draws on advances in the biological, behavioral, and social sciences to: (1)
identify causal
mechanisms that influence developmental trajectories; (2) formulate theories
of change about how to produce better outcomes; and (3) design and test new intervention approaches and measure their effectiveness in reducing barriers to learning and strengthening the foundations
of lifelong physical and mental health.
The overall goal
of this extension
of our existing work in partnership with TFF and Achievement First Bridgeport Academy (AFBA) is to continue and expand our work in Bridgeport focusing in several keys areas: (1) building knowledge about (a) children's emerging skills and areas
of challenge in the social - emotional domain and why these skills are critical to school success, and (b) the ways in which adult stress and skills in the social - emotional domain can impede or foster children's social - emotional skill development; (2)
identifying, deploying, and evaluating strategies to build adult and child skills in social - emotional learning with an emphasis on the Tauck Family Foundation's (TFF) five essential SEL skills; and (3) developing and testing a performance management system for SEL that (a) guides the identification
of strategies, (b) provides a
mechanism for ongoing progress monitoring, feedback, and
changes to practice, and (c) serves as an anchor point for ongoing coaching and support in using SEL strategies.
NCCARF: This project examines the likely impacts on the built environment
of increased intensities in weather - related natural hazard events, in order to
identify the possibilities
of using the regulatory
mechanisms of building construction, housing insurance and planning in climate
change adaptation.
Changes in the activity
of mid-oceanic ridges have long been
identified as a potential
mechanism for sea level
change.
Our results illustrate the utility
of global scale analyses that can aide in
identifying potential ecoclimate teleconnections affected by vegetation
change at regional scales, while simultaneously providing insight into the
mechanisms of the associated ecological responses in affected regions.
As I have also noted in recent public comments, additional
mechanisms have been
identified by which
changes in atmospheric circulation patterns that may be a result
of global warming could be affecting droughts in the American West.
They suggest that the recent oceanic warming has caused the continents to warm through a different set
of mechanisms than usually
identified with the global impacts
of SST
changes.
The course will allow participants to delve deeper into the importance
of adequate adaptation planning, and to acquire tools to
identify and prioritize adaptation options in agriculture sectors, ensure effective coordination and governance for climate
change adaptation actions, and explore
mechanisms for funding and safeguarding livelihoods.
Or, with proper
mechanisms, it didn't
change really and the Earth is still warming as it always has since the end
of the LIA, or
changes may be
identified ad hoc dependent on when certain records were started, the
mechanisms not having existed before then.
Dr. Theodore Landscheidt
identified a
mechanism that may explain
changes in the solar variables that are linked with
changes in Earth's climate: Interactions
of the Sun with the orbital motions
of the four largest planets accelerate and decelerate the Sun in a wobbling and jerky orbit about the center
of mass
of the solar system.
It finds that climate
change will potentially destabilize transboundary river basins, and outlines the linkages among climate
change, water variability and security;
identifies elements in treaty design that could reduce conflict; and assesses the resilience
of treaties ratified between 1948 and 2001, examining the effect
of institutional and allocation
mechanisms under conditions
of variability on cooperation and conflict over time.
This analytical document
identifies allocation provisions and institutional
mechanisms that can mitigate potential conflicts between basin States in the face
of increasing water variability caused by climate
change.
It outlines the linkages among climate
change, water variability and security;
identifies elements in treaty design that could reduce conflict; and assesses the resilience
of treaties ratified between 1948 and 2001, examining the effect
of institutional and allocation
mechanisms under conditions
of variability on cooperation and conflict over time.
The NEPD Group recommends that the President direct federal agencies... to
identify environmentally and cost - effective ways to use market
mechanisms and incentives... and cooperate with allies, including through international processes, to develop technologies, market - based incentives, and other innovative approaches to address the issue
of global climate
change.»
Identify the outcomes (
mechanisms of change) revealed in the analysis
of relevant clinical supervision studies.
The overall goal
of this research is to
identify the social and psychological
mechanisms by which cultural
change and adaptation occur and their relationship to mental health, particularly depression.
Results: Three overarching themes were
identified from Stage One, including: (1) «Experiences
of learned helplessness» (e.g. the association between child conduct problems and family conflict and social isolation); (2) «Perceived benefits and
mechanisms of change» (e.g. the links between positive outcomes and a number
of factors, including key parenting skills, social support, longer - term resilience and commitment, and facilitative organisational practices); and (3) «Challenges in programme implementation» (e.g. cultural discomfort with praise and positive attention, conflict with partners; and organisational difficulties with fidelity, attrition and sustainability).
The first talk
identifies a schema mode model to specify the
mechanism of change in schema therapy from a schema mode perspective for global severity
of personality pathology.