Further exploration of the TCA cycle, using metabolomics, may
identify novel therapeutic targets for CKD and in turn may help us evaluate the effects of promising interventions.»
A better understanding of the function of neuromodulators, such as COX - 2 and TIA - 1, may help
identify novel therapeutic targets for the treatment of epilepsy.»
«We have
identified a novel therapeutic target for the treatment of severe influenza that is effective under conditions where known antiviral drugs fail to protect from death.»
Not exact matches
The resulting data are being combined in a systems biology approach with high - resolution clinical phenotyping and findings obtained with a large array of established and
novel in vitro, ex vivo and in vivo disease models to
identify disease - associated genetic variants, disease - defining molecular signatures, and potential
targets for therapeutic intervention.
AMP T2D focuses on type 2 diabetes genetics, seeking to use and supplement the substantial amount of human genetic data available from people with type 2 diabetes, or at risk of developing it, to
identify and validate
novel molecules and pathways as
targets for therapeutic development.
One of its priorities is to develop relevant strategies to decipher multiple forms of neuromuscular diseases,
identify new
therapeutic targets and foster
novel strategies
for innovative treatments.
Because of the ease with which the CRISPR / Cas9 system can be applied, it has quickly become a robust tool
for generating accurate genetic disease models in the laboratory and
for identifying novel therapeutic targets in the clinic.
My short term goals
for my postdoc are to
identify novel diagnostic and prognostic markers, as well as
novel therapeutic targets, leading to several high impact first authored publications.
Two new precision medicine tests that look beyond cancer genes to
identify novel therapeutic targets have just received New York State Department of Health approval and are now available to both oncologists and cancer researchers
for use at the front lines of patient care.
The goal is to produce a comprehensive «encyclopedia «of gene function, that will help
identify causative factors of human diseases as well as
novel targets for therapeutic intervention.
The results of our studies should
identify potential mechanisms underlying the white matter abnormalities seen in many degenerative diseases, and may reveal
novel therapeutic targets for regenerative medicine.
This model will subsequently be used to find
novel therapeutic targets, to guide genetic screening to
identify individuals with elevated risk
for developing colorectal cancer and to classify patients into sub-groups to select the treatment combination that is optimal
for each patient (personalised medicine).