Sentences with phrase «identify resistance genes»

Methods: Antibiotic resistance was determined using disc diffusion; PCR was used to identify resistance genes.

Researchers now have the tools to identify resistance genes in wild bananas or other plant species.

Using mass DNA sequencing, he recently identified resistance genes even in bacteria in pristine permafrost and deep caves.

By sequencing all of the bacterial DNA in these fecal samples, the investigators identified resistance genes to 16 different antibiotics.

Not exact matches

This makes me happy: a research project has identified a gene that gives wheat plants resistance to one of the most deadly races of the wheat stem rust pathogen, Ug99.

We identified some specific resistance genes that code for receptor - like proteis (RLPs) and described how they operated against the pathogens.

They hope to identify the genes and mechanisms responsible for aflatoxin resistance.

«We're also looking at as many genes as possible in the wild banana and screening them to identify other resistance genes, not only for resistance to TR4 but to other diseases.»

The Sainsbury Laboratory is continuing to identify multiple blight resistance genes that will difficult for blight to simultaneously overcome.

The sequences provide researchers access to 96 percent of all peanut genes and provide the DNA map needed to more quickly identify and genetically tag genes that confer desirable traits, such as drought - and disease - resistance.

Genes associated with tick resistance were identified in all five breeds.

Identifying where resistance genes come from and how they spread somewhat compares to finding patient zero in an outbreak, which is not an easy task.

A small percentage of ash trees in Denmark show some resistance to the fungus and the reference genome is the first step towards identifying the genes that confer this resistance.

A second carbapenem resistance gene, NDM - 1, was identified in 2006 in New Delhi, India.

Geneticists have been identifying genes native to plants that confer resistance to disease.

In one experiment this year, a team led by another CRISPR pioneer, Feng Zhang of the Broad Institute in Cambridge, Massachusetts, targeted the 20,000 or so known human genes, turning them on one by one in groups of cells to identify those involved in resistance to a melanoma drug.

Scientists have so far identified about 250 genes related to appetite, insulin resistance, metabolism, and fat storage.

It will also allow for easier identification of genes that contribute to the bacteria's spread from patient to patient, and more meaningful scientific experiments to understand the bug's resistance to antibiotics or identify new antimicrobial compounds that target specific genes necessary for maintaining these persistent infections.

Johannessen et al. used a highly systematic approach to identify candidate genes and signaling networks that contribute to resistance.

Eduard Akhunov, associate professor of plant pathology at Kansas State University, and his colleague, Jorge Dubcovsky from the University of California - Davis, led a research project that identified a gene that gives wheat plants resistance to one of the most deadly races of the wheat stem rust pathogen — called Ug99 — that was first discovered in Uganda in 1999.

Researchers hope that by sequencing the Chinese chestnut genome, they may be able to identify genes that confer resistance to the blight.

Field reports suggest that not all K13 mutations are capable of causing resistance, and the genetic system developed by Dr. Fidock to study K13, based on DNA repair approaches that are being used in human gene therapy studies, will be critical in identifying real hot spots of resistance.

«Natural resistance to malaria linked to variation in human red blood cell receptors: First study to identify protective effect of glycophorin gene rearrangements on malaria.»

Resistance genes have been identified in corn, but the fungal disease has found ways to sneak around corn's defenses.

Additionally, genes potentially conferring resistance to beta - lactam, aminoglycoside, amphenicol and quinolone antibiotics were identified.

The backers hope that this genetic information will lead to identifying genes for draught, disease, and pest resistance as well as tolerance for poor soils.

Liu's team however have identified MCR - 1, a resistance gene that is carried on a plasmid — a swappable circle of DNA that can be easily passed between bacteria.

The researchers also identified genes responsible for important traits such as disease resistance, wood formation, and stress response; they did not, however, find any genes for ruining presidential golf games.

The Yale - led study performed whole exome sequencing ¬ — a technique for sequencing all the expressed genes in a genome ¬ — on TNBC tumors to identify mutations in specific genes or pathways that may indicate response or resistance to the standard of care, which is anthracycline / taxane (ACT) chemotherapy.

The approximately 3,000 antibiotic resistance genes the researchers identified in soil bacteria typically were not close to such elements.

A companion paper published in BMC Evolutionary Biology by colleagues at the EPA lab in Narragansett, RI, that used a «candidate gene scan» approach — examining SNPs from 42 genes associated with the AHR pathway — also identified AHR2 as a gene that appears to be under selection and is likely to be involved in the resistance.

«And this approach could be used in conjunction with high - throughput screening techniques to identify gene sets associated with problems such as multidrug resistance or benefits, like those related to probiotics.»

He says that, while factors causing DT104's hyperpathogenicity have not been completely identified, the strain seems to owe its resistance to multiple antibiotics to an integron — or gene cluster — structure designated as «Salmonella genomic island 1» (SGI1).

In both communities, the researchers identified areas ripe for bacteria to shuffle and share their resistance genes.

They identified several genes whose absence conferred HIV resistance, some of which had been predicted by previous studies and others that had never been directly tied to HIV infection before.

Genetic Analysis Using an Isogenic Mating Pair of Aspergillus fumigatus Identifies Azole Resistance Genes and Lack of MAT Locus's Role in Virulence.

His group also uses novel genomics approaches to identify genes related to flavor and disease resistance.

Because disease organisms mutate quickly to overcome crop resistance controlled by single genes, researchers are rushing to identify new resistance genes and to incorporate multiple genes into high - yielding varieties, according to Ravi Singh, CIMMYT wheat scientist who participated in the reported study.

Analysing 1612 samples from 15 locations in Southeast Asia and Africa, the researchers were able to identify 20 mutations in the kelch13 gene, a known artemisinin resistance marker, that appear to work in concert with a set of background mutations in four other genes to support artemisinin resistance.

use CRISPR - Cas technology to carry out genome - wide screens of gene - gene, gene - drug and cancer - microenvironment interactions in cells and mice in order to explore fundamental biology and to identify drug targets and drug resistance / sensitisation mechanisms.

Foreign Agricultural 4 months Global Research Team Identifies Pathogen Gene that Wheat Plants Detect to «Switch On «Resistance

Conclusions: MinION sequencing comprehensively identified pathogens and acquired resistance genes from urine in a timeframe similar to PCR (4 h from sample to result).

De Man and his collaborators identified four genes known to confer resistance to beta - lactams, a family of broad spectrum antibiotics often used to treat gram - positive and gram - negative infections.

Results: MinION correctly identified pathogens without culture and, among 55 acquired resistance genes detected in the cultivated bacteria by Illumina sequencing, 51 were found by MinION sequencing directly from the urines; with three of the four failures in an early run with low genome coverage.

In this review, I highlight the main genes known to cause uncommon monogenic forms of diabetes (e.g. maturity - onset diabetes of the young — MODY — and insulin resistance syndromes), as well as describe some of the main approaches used to identify genes involved in the more common forms of T2D that result from the interaction between environmental risk factors and predisposing genotypes.

The pair work together to develop detection methods for new and emerging tomato viruses, identify the tomato genes responsible for virus resistance, and make this information available to plant breeders.

Using new techniques they developed, the investigators identified almost 800 genes in these bacterial communities that confer resistance to antibiotics.

Elizabeth A. Winzeler of the University of California, San Diego, uses big data from whole - genome sequencing and genomics to identify novel drug targets and genes that contribute to pathogen drug resistance.

Therefore, these reference genomes can also enable further studies, such as identifying gene expression changes that explain multidrug resistance and host interaction.

Using high - throughput sequencing of DNA from river sediment up and downstream from the Indian treatment plant [11] we identified a high prevalence of resistance genes from multiple classes of antibiotics.