Sentences with phrase «identify specific markers»

One of the challenges has been to identify specific markers for metastatic BLBC, which would allow development of drugs and prediction of survival.

Not exact matches

Several studies have used cell - surface markers — proteins found on the outer membranes of tumor cells — to identify glioblastoma stem cells; but the specific markers used have been controversial and can not reflect molecular processes going on within tumor cells.

One of their goals at the conference was to pinpoint specific markers of these expressions, and then use them to identify the emergence of humans within the paleoanthropological record.

Scientists at CNRS, Aix - Marseille Université and AP - HM have identified a cerebral marker specific to autism that can be detected by MRI and is present as from the age of two years.

Next steps for the team include identifying microbiota metabolites whose levels are either significantly elevated or depleted during diseases such as IBD or cancer, to find disease - specific markers and explore possible roles for these metabolites in disease progression.

Researchers at Karolinska Institutet have identified cell surface markers specific for the very earliest stem cells in the human embryo.

A newly published International Osteoporosis Foundation (IOF) and European Calcified Tissue Society (ECTS) Working Group position paper [1] proposes measuring specific bone turnover markers (BTMs) in patients who have initiated use of oral bisphosphonates for postmenopausal osteoporosis as a clinically feasible and practical way to identify low adherence.

The cancer cell marker that Johnson and her team identified was a specific change in protein glycosylation, that is, a unique pattern of sugars decorating a protein found on the cell surface.

For the first time, researchers report identifying a biological marker: the over-production of specific genes that could be a diagnostic indicator of mental illness in female psychiatric patients.

To identify and quantitate macrophages within adipose tissue, we immunohistochemically stained sections for the F4 / 80 antigen, a marker specific for mature macrophages (Figure 2; ref.

The scientists then stained the embryo with specific markers to identify cell populations.

Example demonstrating how individual cell classes were identified based on morphology and cell class - specific markers.

Retinal cell classes were identified based on their morphology, location within the retina, and using cell class specific markers (Figures 5 and S2, S3, S4, S5, S6).

There are no specific markers to identify them; however, they are negative for hematopoietic cell markers like CD34 / 45 / HLA - DR and express CD90 / 73/105 on their surface 2, 3, 4.

Within this gene, the deCODE team identified haplotypes, or specific sets of genetic markers, that correspond both to significantly increased risk of stroke and to significantly decreased risk.

Cell markers are helpful tools used to identify a specific immune cell population.

By using immunoprecipitation and mass spectrometry, we identified autoantibodies anti-Adenylate kinase 5 (AK5 - Abs) as specific marker in 10 patients with LE.

Luckily, different cell types tend to have different things on their surfaces, which play particular parts in their specialized roles in the tissue, so it is a matter of identifying and targeting cell - surface markers that are specific to these abnormal cell types.

Researchers use these receptors — or markers — to identify and isolate adult stem cells by «tagging» the chemical messages that bind to those specific receptors on the stem cell with fluorescent molecules.

The antibodies listed above in the immunocytochemistry section were also used on eye sections together with a cocktail of antibodies generated against human - specific markers (HSM) to identify human cells (the Oka blood group antigen, mouse TRA -1-85, 1 ∶ 10 (a kind gift from Peter Andrews, University of Sheffield, Sheffield, UK) together with mouse human nuclear antigen, 1 ∶ 1000, Millipore).

In the 1980s, her research group identified genetic markers that allow prenatal diagnosis and carrier status determination of DMD, and mapped the gene coding for DMD to a specific location on the X chromosome.

Known and novel independent prognostic markers were identified in our cohort of proteasome inhibitor and IMiD - treated patients with long follow - up, including events with context - specific prognostic value, such as deletions of the PRDM1 gene.

This test does not determine breed type, rather, it identifies specific gene markers that are inherited from both parents.

Genetic studies have linked multiple forms of cancer with specific breeds and more will likely be discovered as genetic markers are identified.

Whether a test is mutation - based or marker - based, it identifies only the specific mutation being tested or the association between a specific marker set and the disease.

This test does not determine breed type, rather, it identifies specific gene markers that are highly variable and inherited from both parents.

Additional processing, such as softening bones so they can be sectioned easily, or applying special stains or markers to identify specific types of cells, are occasionally needed.

Genetic testing refers to the process of analyzing a person's genes to identify specific traits or markers, commonly called «genetic characteristics.»