Sentences with phrase «identify vaccine targets»
By beginning with humans, we hoped to identify vaccine targets that will be relevant in humans.
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To generate a rich source of potential vaccine and drug target candidates, the team identified a set of genes that are more active in certain stages of the parasite life cycle and within the parasite's gut.
If we identify these, we can create a vaccine, which targets these proteins.
There he worked on anticancer vaccines, identifying drug targets, preparing vaccine formulations, and testing cellular responses in vaccinated patients.
In 2016, cryo - EM was used to map the structure of the Zika virus (SN: 4/30/16, p. 10), helping to identify possible regions to target with a vaccine or antiviral compounds.
The lack of a vaccine or antiviral drugs to combat the Zika virus has scientists scrambling to identify and better characterize potential drug targets.
Identifying those two molecular targets could help in the design of better vaccine strategies and tumor immunotherapies.»
«Hepatitis C mutations «outrun» immune systems, lab study shows: Study identifies mutations outside of traditional vaccine targets as barrier to vaccine development.»
By identifying novel biological pathways and publishing details of these interactions, the study team aims to help uncover useful targets in developing better vaccines and cancer treatments.
They also need to identify target groups and have a plan to distribute the vaccine.
These findings add an important and previously overlooked component to the causes of dengue vascular leak, identify a new potential target for dengue therapeutics, and support inclusion of NS1 in dengue vaccines.
A study led by St. Jude Children's Research Hospital identifies new path to a universal influenza vaccine emphasizing production of broadly specific antibodies that target multiple flu viruses
Scientists using a powerful mathematical tool previously applied to the stock market have identified an Achilles heel in HIV that could be a prime target for AIDS vaccines or drugs.
Additional uses include precise diagnosis of microbial infection, describing transmission patterns, understanding the genomics of emerging drug resistance and identifying targets for new therapeutics and vaccines.
Nicola was recognized for his longstanding research efforts to understand how herpesviruses cause infections in humans and animals and to identify novel drug and vaccine targets.
We use our mammalian expression technologies to create panels of recombinant pathogen proteins that are then used to identify new subunit vaccine targets for infectious diseases.
This step is essential for parasite transmission to humans and understanding the underlying mechanisms can help to identify new drug - and vaccine targets.
«Each patient is different, so we're developing a personalized vaccine based on specific targets we identify on a patient's tumor,» Overman says.
By understanding erythrocyte invasion in depth, his group aims to identify molecular steps in the invasion process that could be targeted by new drugs or vaccines.
Bhardwaj, a CRI Clip Investigator and Clinical Team Leader who is also involved in CRI's Tumor neoantigEn SeLection Alliance (TESLA), first discussed the computational pipeline that her team is using to identify patient - specific neoantigens to target via vaccines.
He has made several important contributions in this area including identifying a new strain of CHIKV virus, identification of host cellular targets of HIV accessory genes, new novel DNA vaccine approaches for HIV, CHIKV, RSV, Dengue, MERS and Zika among others.
My studies of cancer genomes have led to characterization of multiple pediatric and adult tumor types, to development of methods that identify and characterize changes in genomic heterogeneity, to defining acquired resistance mechanisms to targeted therapies and to designing novel, personalized vaccines for individual patients.
Therefore the group: i) characterizes the specificity of these antibody responses to identify relevant targets for a vaccine; ii) developes new approaches to test antibody responses; and iii) adoptes the immunological analysis in preclinical (in rabbits and macaques) and clinical vaccines studies to identify predictive signatures for the development and prioritization of new HIV - 1 vaccine candidates.
Serogrouping identified isolates expressing capsule antigens targeted by the vaccine.
Flu viruses constantly change, meaning that each year, scientists identify the flu strains in circulation and target the vaccine accordingly.
Coverage rates for vaccines recommended for all children were higher than the state average for Aboriginal children (93 % fully vaccinated in Sydney West v. 87 % in NSW) and also for non-Aboriginal children (91 % v. 90 %, respectively).3 The steering group decided that the main reasons for low coverage of 7vPCV in Aboriginal children were likely to be a lack of knowledge about the targeted program among both parents and providers, and failure in identifying eligible infants.