Proven experience in fault isolation, physical / construction analysis,
identifying failure mechanisms, characterizing manufacturing defects and new semiconductor materials.
In this investigation, I looked at history to
identify failure mechanisms.
Not exact matches
But
failure to
identify the detailed
mechanism by which this happens has left many geneticists doubtful that it occurs at all.
According to the research team, the
failure of these types of outcomes monitoring systems to produce measurable improvements in outcomes may be related to difficulties in
identifying mechanisms that translate reports into changes in how surgical care is provided.
But
failure to
identify the detailed
mechanism by which this happens has left many geneticists doubtful that it happens at all.
Additional limitations to the traditional approach include: costly
failures to replicate positive results in larger trials; difficulty in determining the reasons for negative results; low yield in terms of
identifying disease or intervention
mechanisms due to an exclusive focus on symptom change and clinical endpoints; and, the expensive and very lengthy practice of first establishing multi-component psychosocial treatments followed by years of «unpacking» studies.
Her work on the genetic
mechanisms of cardiomyopathies and muscular dystrophies has
identified several genes that are important for cardiac and skeletal muscle membrane stability and produced insights into how heart
failure and muscle dysfunction occur.
First, we clinically and genetically characterize different cardiomyopathy cohorts to
identify novel disease genes, to understand the
mechanisms for heart
failure, and to improve prognosis.
A related challenge is ensuring that rigorous accountability
mechanisms are put in place so that success can be readily
identified and
failures addressed.
From this conceptual and empirical review, it is concluded that an overemphasis on clinical outcomes carries unnecessary risks (e.g., weak causal reasoning and a
failure to
identify mechanisms of change), while underemphasizing the several benefits of a more inclusive approach (e.g., increasing outcome research and improving supervision).