Sentences with phrase «identifying gene expression signatures»

By identifying gene expression signatures common to sight, touch and hearing, neuroscientists at the University of Geneva (UNIGE), Switzerland, discovered a sensory «lingua franca» which facilitates the brain's interpretation and integration of sensory input.

Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.

Not exact matches

Using support vector machine recursive feature elimination, the researchers identified three gene expression signatures that predicted therapy responses.

For example, the researchers were able to identify previously unknown gene expression differences between the neural stem cells that give rise to the brain's deep structures versus its neocortical surface, and to show that molecular signatures of different neural cell types arise much earlier in brain development than previously realized.

With the development of novel genomics technologies, such as Next - Generation Sequencing, numerous new mutations and gene expression signatures have been identified, allowing us to better understand the molecular heterogeneity of hematologic diseases and to better stratify and assess risk for cancer patients.