They further investigated the genomic basis of divergence among the cultivated populations for
identifying genes controlling important traits.
And Dr. Ludovic Orlando from the Centre for GeoGenetics at the University of Copenhagen concludes: «Perhaps even more exciting as it represents the hallmark of animal domestication,
we identify genes controlling animal behavior and the response to fear.
Here,
we identified genes controlling greening directly downstream of the GATAs by integrating data from RNA - sequencing and microarray data sets.
To date, these data have been studied with a two - step process cumulating in an integrative data analysis to
identify genes controlling metastatic colonisation.
Not exact matches
The method
identifies gene sets that show evidence for positive selection in comparison with matched
controls, and thus highlights
genes for further functional studies.
We
identify key candidate
genes that may
control rate - limiting steps during lactation and outline future work in the endeavor to discover the biological underpinnings of poor lactation performance in women attempting to breastfeed.
Their landmark findings will open the door to
identify gene variants
controlling skin microbiota and to define their link to various diseases such as skin inflammatory disorders.
«We now need to
identify how this effect is pass through multiple generations by investigating the effects alcohol has on the genome and epigenome (molecules that
control gene translation),» said Cameron.
Next, Anderson and his colleagues used a set of genetic tools to
identify exactly which neurons were responsible for the effect on aggression and to see if the
gene that encodes for Tk also
controls aggressive behavior by acting in that cell.
The researchers
identified for the first time master
genes that they believe
control hundreds of other
genes which are linked to Alzheimer's disease, Parkinson's disease, post-traumatic stress disorder, stroke, attention deficit hyperactivity disorder, autism, depression, schizophrenia and other disorders.
The findings by a team of Massachusetts General Hospital (MGH) investigators, which will be published in the April 24 issue of Cell and are receiving advance online release, support the importance of epigenetics — processes
controlling whether or not
genes are expressed — in cancer pathology and
identify molecular circuits that may be targeted by new therapeutic approaches.
«By analyzing the blood of children of
controls and comparing it to children of bipolar patients, we
identified several
genes or markers that can explain the increased risk.»
In addition to
identifying several characterized developmental
genes, the approach revealed previously unsuspected genetic subdivisions of the thorax, which may
control the disposition of pattern elements.
By tweaking different fly
genes and counting how many neuron types were produced as the flies matured, the team
identified a network of five
genes that work together like coordinated
control switches to guide the precursor cells» transformation to mature neurons.
University of Illinois researchers have
identified candidate
genes controlling the accumulation of phenolic compounds in broccoli.
«
Gene that
controls soybean seed permeability, calcium content,
identified.»
The team's next goal is to
identify genes that interact with GmHs1 - 1 and understand how they work together to
control calcium and possibly other mineral content.
Using previous data, Orkin and his team
identified the BCL11A
gene as a candidate for
controlling the molecular switch.
This could be transformative as we
identify similar
genes that
control calcium levels in other legumes.»
Molecular geneticists dream of having a similarly comprehensive view of networks that
control genes: For example, they would like to
identify rules explaining how a single DNA sequence can express different proteins, or varying amounts of protein, in different circumstances (see p. 80).
That's why sequencing the genome was important, he said, because it will help
identify all the
genes and enzymes in the genome needed for hydrocarbon production and
control of this production.
Decades of work in developmental biology have provided a start: Biologists have used mutant frogs, flies, mice, chicks, and fish to
identify some of the main
genes that
control a developing cell's decision to become a bone cell or a muscle cell.
In a study exploring the molecules
controlling osteoclast differentiation in the cancer setting, Ell et al. have
identified miRNAs (microRNAs are small noncoding RNAs that regulate
gene expression) whose levels were consistently down - or up - regulated in differentiating osteoclasts.
They then
identified the putative causal mutations in
genes controlling shattering (a key domestication trait among cereal crops).
To further
identify the role of TAZ, the research team studied breast tissue at different stages of development using two groups of mice: a
control group with the TAZ
gene and an experimental group of knock - out mice with the TAZ
gene deleted.
A Kansas State University wheat geneticist is part of a breakthrough study that
identifies one of the wheat
genes that
controls response to low temperature exposure, a process called vernalization.
A traditional way to target a candidate
gene is to
identify a molecule or process important to, say, emotion, and then go back and find the
genes that
control it.
After analyzing brain tissue samples, the researchers
identified an area of the
gene where a single change reduced BDNF levels in the hypothalamus, a key area that
controls eating and body weight.
Basel scientists have now
identified a network of
genes that
controls fundamental properties of neurons and is important for human brain activity, memory and the development of schizophrenia.
Using the recently completed tomato genome sequence they then
identified the
gene as SlGLK2 — a so - called transcription factor, which
controls when and where other
genes are switched on or off.
Using sophisticated genetic sequencing technology, King and Yin
identified a common set of
genes that are
controlled by a shared network of genetic regulators known as microRNAs.
The
gene that
controls shell thickness, creatively named SHELL, was
identified in 2013 by researchers at Orion, Cold Spring Harbor Laboratory in New York and the Malaysian Palm Oil Board (MPOB), a government research institute based near Kuala Lumpur.
To
identify genes that might be relevant for drug discovery, the investigators plumbed DNA data from patients with coronary disease and from healthy
controls.
For the first time, researchers have
identified a long non-coding ribonucleic acid (ncRNA) that regulates
genes controlling the ability of heart cells to undergo repair or regeneration.
Indeed, the team
identified high variation in adjacent «normal» tissue samples, which are typically used as
control samples for comparison in analyses based on mean
gene expression.
Researchers have
identified many of Short - root's
gene targets, but weren't sure what
controlled the Short - root master switch itself to kick off the cascade.
They
identified a simpler 2 - node network — where the stripe
gene is directly
controlled by both activation and repression from the morphogen sensor
gene - that replicates the stripe - forming ability in its simplest form.
Now, synthetic biologists have solved the last piece of the poppy puzzle,
identifying the
gene that
controls a key intermediate step between the first and second halves of the process, which had already been sorted out.
Peter Meyer, a molecular biologist at the University of Leeds, and his colleagues
identified a
gene they labeled Sho (for shooting), which
controls production of cytokinins, hormones that delay aging in plants.
Increasingly local adaptation to climate is being studied at the molecular level by
identifying which
genes control climate adaptation and how these vary between individuals.
Though this study doesn't yet
identify the mechanism that
controls gene activity for generations after a famine, the findings build a foundation to do so, Baugh said.
The researchers also
identified genes that
control sugar content, but realistically, there's no way to directly boost the sugar in commercially grown tomatoes, Klee says.
The team has
identified several ways that naturally occurring
gene variations can
control both a person's height and their risk of coronary heart disease.
Using a slew of molecular techniques, the team
identified the color - stealing culprit in white grapes as a mobile fragment of DNA, called a retrotransposon, which inserts itself into the
gene controlling pigment production.
Previously, Shozo Kobayashi of the National Institute of Fruit Tree Science in Tsukuba, Japan,
identified a specific
gene that
controls the production of this pigment in black - skinned grapes.
This is the first study in human trials to
identify genes driving acute peanut allergic reactions using a double - blind placebo -
controlled approach with comprehensive sequencing of
genes expressed before, during, and after they ingested peanut.
In his previous work, CSHL Associate Professor Zach Lippman and Israeli colleagues
identified a rare example of hybrid vigor involving a genetic defect in the
gene that makes florigen, a hormone that
controls the process of flowering and flower production.
One surprising finding from the study co-led by Johns Hopkins, Ehret says, was that many of the new sites
identified were near
genes that are active in cells that line the inside of blood vessels, suggesting those cells are somehow involved directly in blood pressure
control.
Professor Seymour said: «To support the tomato industry and further improve consumer satisfaction with new tomato varieties, a major scientific goal has been to
identify genes that allow the targeted
control of fruit softening without impacting other aspects of ripening.
«This is the first time a
gene that
controls the timing of bud break in trees has been
identified.»