Not exact matches
In phase I trials, researchers test a new
drug or treatment in a small group of people for the first time to evaluate its safety, determine a
safe dosage range, and
identify side effects.
«At Exeter we are already developing specific psychological therapies, running clinical trials of novel
drug approaches and using - cutting edge genetic techniques to
identify new targets for
safe and effective therapies and to allow us to use current treatments in a more focussed way.»
A team from Oxford University, led by Dr Grant Churchill and Dr Sridhar Vasudevan of the Department of Pharmacology, in collaboration with Professor Phil Cowen of the Department of Psychiatry, used a database of «failed»
drugs, found to be
safe but ineffective for their proposed use, to
identify ebselen as a possible alternative to lithium, the main treatment for people who are bipolar.
A follow - up structure - based discovery campaign to develop
safer opioids
identified PZM21 as both a potential
drug candidate and experimental tool to find other
safer opioids.
Identification of new therapeutic applications for known
drugs: Boston Children's investigators have developed and characterized a wide variety of preclinical assays and animal models useful for
identifying additional therapeutic indications for
safe compounds.
Engaging students in
drug education programs assists them to make healthier and
safer choices,
identify high risk situations, and develop a range of strategies to prepare them for challenging situations.