Sentences with phrase «identifying small molecule drugs»

«They also provide a promising strategy for identifying small molecule drugs designed to treat Alzheimer's disease and other neurological disorders.»

Published June 25, 2015 in Molecular Cell, the new study identifies a small molecule drug that specifically blocked the first step of autophagy, effectively cutting off the recycled nutrients that cancer cells need to live.

Not exact matches

«We could apply the strategy used in this study to quickly identify and design small molecule drugs for other RNA - associated diseases,» explained study first author Sai Velagapudi, a research associate in the Disney lab.

The goal of early SMA drug discovery programs has been to identify small molecules that induce the SMN gene to produce sufficient levels of protein to improve motor neuron functioning in affected patients.

«The next step is to identify antibodies and small - molecule drugs that can successfully target Helios or genes in the Helios pathway,» says the study's lead author, Hye - Jung Kim, PhD, of Dana - Farber.

Using the new method, published on July 31, 2017 in Nature Chemistry, the TSRI scientists identified more than 100 human proteins that are likely to be targetable with small molecule, pill - based drugs.

Many researchers are trying to find ways around this; one possibility is identifying small drug - like molecules that could replace the reprogramming - factor / virus delivery combination.

«Scientists can now, at the click of a button and at a single online location, rapidly identify the biological and structural characteristics of an actual or potential drug target, find the genes and proteins that it interacts with, assess its structural druggability and identify any small molecule chemical inhibitors.

The Alzheimer's Innovation Award will help advance particularly critical components of Mucke's ongoing drug discovery program to identify and optimize small molecule compounds that potently and safely reduce tau levels in the brain.

Phenotypic screening of small molecule libraries using iPSC - based models to identify novel drug candidates and disease mechanisms.

The team screened a small molecule compound library and identify a drug, which they call CLP257.