Sentences with phrase «idiopathic myelofibrosis»
Methods: We obtained DNA samples from patients with polycythaemia vera, essential thrombocythaemia, or idiopathic myelofibrosis.
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Findings: A single point mutation (Val617Phe) was identified in JAK2 in 71 (97 %) of 73 patients with polycythaemia vera, 29 (57 %) of 51 with essential thrombocythaemia, and eight (50 %) of 16 with idiopathic myelofibrosis.
Background: Human myeloproliferative disorders form a range of clonal haematological malignant diseases, the main members of which are polycythaemia vera, essential thrombocythaemia, and idiopathic myelofibrosis.