«This is exciting because
if genes affected differences between individuals in these traits, it means they could also change in response to natural selection,» said Dr Bolund.
Not exact matches
Strangely enough, former lovers somehow make an imprint on the brain and possibly
affect genes, especially
if there was past fluid exchange.
By tracking activity in almost all the
genes of a free - living archaeon — which, like a bacterium, is a prokaryote — Bonneau was recently able to piece together how the
genes affected one another's expression, enabling him to map the organism's «control circuit» as
if it were a machine.
To find out
if this effect on testosterone production might
affect mice's fertility, the team knocked out the
gene for osteocalcin in a group of the rodents.
If they could find an
affected gene in the boy's family, it might lead researchers to the causes of more common, sporadic cases of Beckwith - Wiedemann, too.
But he warns that the
gene could have undesirable side effects in some plants: «
If we indiscriminately make a plant insensitive to ethylene, we may
affect its response to diseases or to pests.»
A change in every 100th base could
affect thousands of
genes, and the percentage difference becomes much larger
if you count insertions and deletions.
But because the
gene appears to
affect only the cat's color, white tigers are simply genetically healthy variants of Bengal tigers, which,
if bred carefully, might still survive well in the wild.
«Fetal sex determination allows targeting of invasive testing to see
if the female fetus is carrying two mutant copies of the CAH
gene and is therefore
affected.
Unlike genetic mutations that
affect DNA and the genome, epigenetic markers turn
genes on and off to regulate cell processes, which
if altered may lead to disease, he explains.
Studying how
genes affect different drugs manufactured by different companies gives Poirier greater influence on future drug development, he feels, which would not be possible
if he was employed at any one pharmaceutical research lab.
If getting rid of some of the
genes affected the bacteria's ability to fight off phages, that result suggested the group of
genes was a defense system.
In contrast,
if the
gene itself is deleted by a genetic manipulation, blood vessel growth is not
affected.
If chemogenetics turns out to have harmful effects, the
affected brain area could still be surgically removed, Kullmann, because the virus used to deliver the
gene only spreads a few millimetres.
Women are
affected only
if both their X chromosomes carry the defective
genes.
If it turns the wrong
genes on or off, it can
affect health and disease just as surely as can changes in the DNA itself.
When they screened the KE family to see
if some carried a defect in this
gene, all
affected members turned out to share a specific mutation that apparently rendered FOXP2 inactive, the group reports in the 4 October issue of Nature.
«
If you can find a
gene for blond hair that exists in Melanesia and nowhere else,» Myles says, «then there's no reason why those sorts of
genes don't exist all over world in underrepresented populations, and
affect not only hair pigmentation, but also disease - related traits.»
«Take the test» would be the advice of proponents of
gene screening —
if only because in your next pregnancy, doctors will know whether you are at risk and whether you should be offered prenatal diagnosis and the option of terminating
affected fetuses.
She's found that the physical arrangement of DNA inside a cell's nucleus can
affect cancer
genes: for example,
if a
gene gets stuck in a folded - up piece of DNA, proteins that normally turn it on can no longer access it.
«
If you want to discover
genes that
affect the brain, the only way we know how to do that is by analyzing tens of thousands of brain scans and their corresponding genetic data.
The technical evaluation of projects may require the provision of additional data such as information on the genetic modification of your mutant mouse line
if applicable (e.g.
affected gene, MGI ID of the
gene, type of mutation, ES - cell line used, genetic background (e.g. number of backcross generations), safety level, description of DNA modification, vector, remaining non-recipient DNA, donor organism), mutant phenotype (s), special housing or care requirements, current sanitary status, and intellectual property rights (who generated the mouse line, owner of the mouse line)
Their preservation in the zebrafish allows us to visualize in this transparent genetic vertebrate model whether these variants are just neutral or
if they disrupt the regulation of one the neighbor
genes, possibly revealing the actual
gene affected in AMD human patients.
«We're gaining some sense of confidence that there are a certain number of
genes that,
if adversely
affected, predispose patients toward having this problem and possibly not healing well,» Koltun said.
If the lens is cloudy because of a mutation in the
gene that
affects the lens, then the pupil will look white.
But probably lots of characteristics might play a role... for example, any
gene affecting where and when a predator is active (
if it's best not to overlap too much with toads) might help the predator to survive.
An individual may still be a carrier of (or
affected with) a disease
if no variants or only one variant is found in the relevant
gene.
The company, intrigued with the results, wanted to know
if chromium was
affecting gene expression in fat metabolism.
DNA methylation, which is reversible
if occurs at regulatory elements of the genome
affects the transcription of neighboring
genes.
If a drug increases levels of dopamine, say, and you have a
gene that causes a chain reaction that leaves more dopamine swimming about in your brain, the drug is going to
affect you differently than it would someone whose
genes make dopamine less available to them.
The most striking results were those showing that soybean oil significantly
affects the expression of many
genes that metabolize drugs and other foreign compounds that enter the body, suggesting that a soybean oil - enriched diet could
affect one's response to drugs and environmental toxicants,
if humans show the same response as mice.
Tests to see
if you have the
gene that causes CF. CF is a disease that
affects breathing and digestion.
What
if you had a
gene mutation that could
affect your ability to get and / or stay pregnant.
If it
affects your ovaries / testes, then your offspring will have different
genes than you.
So,
if we managed — let's say, the diet
gene, the AIP
gene, right, then that's gonna
affect those autoimmune
genes from flipping on...
Genetic testing is available for you to see
if you or your partner carry
genes for Cystic Fibrosis, Sickle Cell, Spinal Muscular Atrophy and other disease that may
affect your decision making.
Gene patents,
if upheld by the Supreme Court, could
affect genetic research and access to genetic tests for patients
Researchers have identified the
gene mutation that causes NEwS, and a DNA test is now available that allows breeders to avoid producing
affected puppies by never breeding two dogs to each other
if they are both carriers of the abnormal
gene.
It only becomes
affected if both its parents carry the defective
gene.
To find this out, test mating is done to a dog that is
affected with the genetic problem (resulting usually in puppies that are both
affected and non-
affected carriers) or by inbreeding to a related dog that also doesn't show the signs of being
affected (usually litter mates are used) this will usually result in some puppies free of the problem, some puppies as carriers, and some puppies
affected if both dogs carry the problem
gene (this is not as accurate as breeding to an
affected dog, but you are less likely to have to put all the puppies down).
Although great strides have been made in identifying genetic markers and developing screening tests for many
gene - based diseases, there are no test yet for PLN, PLE, or RD. Therefore, the breed club's health committee recommends that close relatives of dogs with these diseases not be bred and that periodic tests be done on the relatives of
affected dogs to determine
if the disease is present and help establish a baseline for research.
If the breeder is very careful,
affected pups can be used wisely to prevent loss of quality, but still remove the
affected genes by only breeding the
affected pups to known non-carrier relatives.
Because there is more than one form of PRA,
if there should happen to be a second form in the breed and your dog had the
genes for that type it would be possible to test your dog «for PRA» using the PRCD test with clear results when the dog is actually
affected — but with a different form of PRA.
To find this out, test mating is done to a dog that is
affected with the genetic problem (resulting usually in puppies that are both
affected and non-
affected carriers) or by inbreeding to a related dog that also doesn't show the signs of being
affected (usually littermates are used) this will usually result in some puppies free of the problem, some puppies as carriers, and some puppies
affected if both dogs carry the problem
gene (this is not as accurate as breeding to an
affected dog, but you are less likely to have to put all the puppies down).
If a male is
affected, he would have received the defective
gene from his carrier mother.
If one recognizes that with regard to heredity of
genes all living things are either CLEAR, NORMAL / CARRIERS OR
AFFECTED it becomes clear that testing of whole litters is the only way to be aware of those factors present in a brood bitch / stud dog.
If inheritance is complex, even more dogs might carry genes that could produce the disease if they happen to be mated with a dog that can «fill in the blanks» to produce affected pup
If inheritance is complex, even more dogs might carry
genes that could produce the disease
if they happen to be mated with a dog that can «fill in the blanks» to produce affected pup
if they happen to be mated with a dog that can «fill in the blanks» to produce
affected pups.
As there is currently no DNA testing available for Beagle Epilepsy and no way to determine
if a Beagle is
affected with or carries the
gene (s) for Epilepsy, the best we can do as breeders is to be completely honest when we produce a Beagle who has seizures.
Again, there is no test available to determine
if a Beagle will be
affected by or carry the
gene (s) for IVDD, so Beagle breeders should avoid breeding dogs who are known to have IVDD or produce puppies
affected with IVDD.
There is a genetic test available that can tell you
if a dog is
affected by ataxia or
if it is a carrier of the faulty
gene.