Not exact matches
You need the oligonucleotides to stitch genes together, and as far as I know, most companies will check the order
if the
sequence represents that of a dangerous
virus.»
Joy: Yeah, but the point is we have the technology now to
sequence and manufacture vaccines fairly quickly; and ideally they wouldn't be grown in eggs or whatever, right; because what
if it starts as a
virus in chickens or something, and we're screwed.
We have a short time period, and so we do about a billion experiments at a time, where we can genetically engineer our
viruses to express different random peptide
sequences and we can, you know, [in] about a one microliter sample we can introduce about a billion different
viruses to a semiconductor wafer or an electrode and have them see
if they can actually molecularly imprint it or try to do a chemical and physical map to it so that they can actually then have a template to grow that material.
Genome
sequencing of specimens from both Canada and Mexico will help us to understand
if the
virus has mutated which may help us to explain the increased severity of the cases in Mexico.
In flu surveillance, researchers look primarily for the genes encoding the
virus's surface proteins, hemagglutinin and neuraminidase;
if they
sequence the so - called internal genes as well, they might detect new genes slipping into human
virus strains in the run - up to a pandemic, they say.
That MLV
sequence, highly conserved among
viruses of its class, would presumably have been found
if XMRV was present, they said.
These assassins can read the RNA
sequence of any
virus DNA they run into, recognize
if it matches the information they've stored in their DNA, trap it and chop it up.
«This useful contribution underlines the value of routine surveillance of Zika and other emerging
viruses: we can learn a lot from genome
sequencing but that can happen only
if surveillance systems are in place to detect and
sequence the
viruses.
Recent
sequencing projects investigating
virus diversity, to see
if different strains have different disease impacts, have excluded regions of repeating
sequence, as they are more technically challenging.
Even scarier is what Edward Dubovi, Ph.D., director, Virology Laboratory Animal Health Diagnostic Center, College of Veterinary Medicine, Cornell University, said: «We are
sequencing all the time to determine
if the H3N2
virus diverges into different clades (almost like substrains of flu).