Sentences with phrase «imaging agents in»

Dr Kelly was employed by Amersham (a predecessor to the defendant company) in 1985 to head a new research group to work on heart imaging agents in a race with Amersham's main competitor Du Pont.

The SNMMI Clinical Trials Network is dedicated to facilitating the use of ALL imaging agents in multi-center clinical trials of investigational therapeutics.

She also conducts clinical research evaluating prognosticators of outcome in patients with liver, bile duct and liver tumors and investigates new imaging agents in pancreas and liver cancers.

Sakuma S, Kumagai H, Shimosato M, Kitamura T, Mohri K, Ikejima T, Hiwatari KI, Koike S, Tobita E, McClure R, Gore JC and Pham W. Toxicity studies of coumarin 6 - encapsulated polystyrene nanosphere conjugated with peanut agglutinin and poly (N - vinylacetamide) as a colonoscopic imaging agent in rats.

Not exact matches

In the drive to improve early detection and treatment of cancer, a pair of Toronto scientists has developed a unique technology that combines contrast agents with targeted, long - lasting nano - particles for use in multiple medical imaging platformIn the drive to improve early detection and treatment of cancer, a pair of Toronto scientists has developed a unique technology that combines contrast agents with targeted, long - lasting nano - particles for use in multiple medical imaging platformin multiple medical imaging platforms.

Lantheus Holdings Inc.'s shares are headed for one of their biggest losses since the maker of medical - imaging agents and products went public in June 2015.

Chiu and Kelly were involved in the development of a compound called P53, a key component in an imaging agent called Myoview which went on to generate global...

Test that uses imaging agent to detect protein buildup may get government funding, but only in limited cases

For this research, a total of 28 subjects were imaged with a variety of imaging modalities, including standard imaging with computed tomography, magnetic resonance imaging and molecular bone scan (SI); PET with a common radiotracer called fluorodeoxyglucose (FDG - PET); and PET with computed tomography and the agent Zr - 89 IAB2M (IAB2M PET / CT) assessed in escalated doses.

More data are needed to understand its clinical value but, if results are favorable, this imaging agent could play a critical role in the standard of care for prostate cancer.»

The MPI that uses clinically - approved, iron oxide - based MRI contrast agents is capable of 3D, high - resolution imaging in real time.

Direct positron imaging is a nuclear medicine technique that allows researchers to gain physiological information from radiolabeled imaging agents that bind to targets in the body, which are then imaged with a specialized detector.

New results in animals highlight a major safety concern regarding a class of magnetic resonance imaging (MRI) contrast agents used in millions of patients each year, according to a paper published online by the journal Investigative Radiology.

In the study, the imaging agent — Ga - 68 prostate - specific membrane antigen (Ga - 68 PSMA)-- used with positron emission tomography and computed tomography (PET / CT), changed management in 44 % more cases than another widely used agenIn the study, the imaging agent — Ga - 68 prostate - specific membrane antigen (Ga - 68 PSMA)-- used with positron emission tomography and computed tomography (PET / CT), changed management in 44 % more cases than another widely used agenin 44 % more cases than another widely used agent.

In addition, therapeutic agents can be developed and tested using imaging technologies that are directly translatable to the clinic.

«Small amounts of gadolinium deposit in certain parts of the brain in people who undergo repeated gadolinium - based contrast agent enhanced exams,» said Vikas Gulani, MD, PhD, Associate Professor of Radiology, Urology, and Biomedical Engineering at Case Western Reserve University School of Medicine, member of the Case Comprehensive Cancer Center, and Director of Magnetic Resonance Imaging at University Hospitals Cleveland Medical Center.

In their current study, described online today in Science, Discher and his colleagues copied short snippets of the CD47 protein, known as peptides, and attached them to nanoparticles designed to ferry either imaging agents or anticancer compounds to tumorIn their current study, described online today in Science, Discher and his colleagues copied short snippets of the CD47 protein, known as peptides, and attached them to nanoparticles designed to ferry either imaging agents or anticancer compounds to tumorin Science, Discher and his colleagues copied short snippets of the CD47 protein, known as peptides, and attached them to nanoparticles designed to ferry either imaging agents or anticancer compounds to tumors.

A relatively new biomarker called prostate - specific membrane antigen (PSMA) is the bullseye for three new magnetic resonance imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range of tumor types, according to research unveiled at the 2015 annual meeting of the Society of Nuclear Medicine and Molecular Imaging (imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range of tumor types, according to research unveiled at the 2015 annual meeting of the Society of Nuclear Medicine and Molecular Imaging (Imaging (SNMMI).

For this study, 10 subjects with Alzheimer's underwent PET following the injection of three radiotracers: fluorine - 18 fluorodeoxyglucose (F - 18 FDG), which images regional metabolic activity; carbon - 11 Pittsburgh compound B (C - 11 PiB), which has an affinity for amyloid plaques; and F - 18 AV - 1451, an emerging imaging agent that binds to tau in the brain.

Polarized xenon is also used as a contrast agent to enhance images in experimental magnetic resonance imaging (MRI) of human lungs, but conventional systems for producing and using this gas can be as big as a car.

A newly devised tumor - specific fluorescent agent and imaging system guided surgeons in real time to remove additional tumors in ovarian cancer patients that were not visible without fluorescence or could not be felt during surgery, reports Alexander L. Vahrmeijer MD, PhD, head of the Image - guided Surgery group in the Department of Surgery at Leiden University Medical Center in the Netherlands.

For the first time, researchers have confirmed an association between a common magnetic resonance imaging (MRI) contrast agent and abnormalities on brain MRI, according to a new study published online in the journal Radiology.

Another project enabled the first FDA - approved imaging agent that could be used in PET scans of Alzheimer's patients who were still alive.

Frangioni is also CEO of Curadel, a company he started in 2014 with the purpose of developing NIR contrast agents and imaging systems to help surgeons identify glands, blood vessels, nerves, lymph nodes, and tumors during operations.

What makes this technique novel is the accompaniment of an imaging agent known as Ga - 68 DOTATOC, which binds to somatostatin receptors in neuroendocrine cells that use the hormone somatostatin to mediate endocrine function, the release of neurotransmitters and cellular proliferation.

In magnetic resonance imaging (MRI), contrast agents are used to enhance the imaging of tissue structures.

«These recent published findings are showing that gadolinium deposition in tissue could be more common than previously thought, so the development of a natural contrast agent alternative is certainly a high priority for the imaging community and, of course, patients.»

In addition to the thyroid and parathyroid imaging contrasts, Frangioni and Choi are particularly excited about another single molecule NIR agent that they have recently developed to light up cartilage.

«This is the first non-metallic, biodegradable, natural MRI contrast agent tested in humans,» explained Guoying Liu, Ph.D., Director of the NIBIB Program in Magnetic Resonance Imaging and Spectroscopy.

The new method, described in a scientific paper that will be published Feb. 18 in The Lancet Oncology, is a modification of magnetic resonance imaging that employs a novel contrast agent to find tumors.

A further chemical modification in the ProCA32 MRI contrast agent improves the ability for the compound to be retained in blood for a longer period of time, permitting a longer window for imaging and tumor detection.

Specifically, the imaging agents developed in the laboratory for use in fluorescence molecular tomography, are now even being translated into the clinic for human diagnostic applications.

Altes and her team decided to use a specific form of helium, helium - 3, as a harmless contrast agent in conjunction with magnetic resonance imaging (MRI) to visualize lung function.

Exposure to the nerve gas agents sarin and cyclosarin has been linked in several studies to changes in magnetic resonance imaging (MRI) that are associated with cognitive impairments in Gulf War veterans.

Baltimore, Md. (Embargoed until 12:30 pm EDT on Monday, June 8)-- A relatively new biomarker called prostate - specific membrane antigen (PSMA) is the bullseye for three new magnetic resonance imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range of tumor types, according to research unveiled at the 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range of tumor types, according to research unveiled at the 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (Imaging (SNMMI).

Emerging molecular imaging agents join tumor - seeking antibodies and signaling radioisotopes in one radiopharmaceutical that is injected at the time of imaging in order to track and report active receptors.

18F - AV - 1451 is a brain imaging agent used in PET (Positron Emission Tomography) Scans.

Dr. Sanford, who is both a member of the National Academy of Sciences and recipient of a MacArthur «genius grant,» has designed molecules that can be used to store energy in batteries, serve as new medical imaging agents, convert carbon dioxide into fuels, or serve as pharmaceuticals to treat disease.

After receiving a master degree in Biotechnology at the University of Verona (Italy) in 1998, I joined the neuroscience centre of GlaxoSmithKline (GSK), a large research - based pharmaceutical company based in Verona (Italy) and Harlow (UK), where I pioneered the use of functional magnetic resonance imaging (MRI) to describe the neural substrates modulated by pharmacological agents, a line of research that I also pursued to obtain a PhD degree in biomedical imaging with the University of Verona.

An In Vivo Evaluation of the Effect of Repeated Administration and Clearance of Targeted Contrast Agents on Molecular Imaging Signal Enhancement Jason E. Streeter, Paul A. Dayton Theranostics 2013; 3 (2): 93 - 98.

Fluorescent and luminescent materials, such as yttrium aluminum garnet doped with different metal ions (rare earths or transition metals), have found applicability in various fields, from optoelectronics (i.e.: lighting systems, LCDs, CRTs, lasers) to aerospace (i.e: thermal barriers) and biotechnological applications (i.e.: fluorescence marker, contrast agent in medical imaging, imaging screens, drug delivery etc).

Title: Quantifying the attenuation of the ketamine pharmacological magnetic resonance imaging response in humans: a validation using antipsychotic and glutamatergic agents Author: O. M. Doyle et al..

If a non-PET agent is identified, the CTN will assist in securing imaging sites and manufacturers appropriate for the trial.

Specifically, I am leading a Project focusing on Nitrogen - Vacancy centers in nanostructured diamond as a means to hyperpolarize nuclear spins for the production of hyperpolarized agents for imaging of cells and tissues in living organisms.

SEATTLE — An imaging agent discovered by a Washington State University researcher that homes in on prostate cancer will be developed for human clinical trials thanks to a two - year $ 2 million federal Small Business Innovation Research grant.

In parallel, I cultivate my long - term interest in novel agents for imaginIn parallel, I cultivate my long - term interest in novel agents for imaginin novel agents for imaging.

«Deficient neuron - microglia signaling results in impaired functional brain connectivity and social behavior» Y. Zhan, R.C. Paolicelli, F. Sforazzini, L. Weinhard, G. Bolasco, F. Pagani, A. L. Vyssotski, A. Bifone, A. Gozzi, D. Ragozzino, C.T. Gross Nature Neuroscience 17 (3), 400-4006 (2014) «USPIO - loaded Red Blood Cells as a biomimetic MR contrast agent: a relaxometric study» A. Boni, D. Ceratti, A. Antonelli, C. Sfara, M. Magnani, E. Manuali, S. Salamida, A. Gozzi, and A. Bifone Contrast Media and Molecular Imaging 9, 229 - 236 (2014) «Distributed BOLD and CBV - weighted resting - state networks in the mouse brain» F. Sforazzini, A.J. Schwarz, A. Galbusera, A. Bifone, and A. Gozzi NeuroImage 87, 403 - 415 (2014) «Antimicrobial peptides design by evolutionary multiobject optimization» G. Maccari, M. Di Luca, R. Nifosì, F. Caldarelli, G. Signore, C. Boccardi, and A. Bifone PloS Computational Biology 9 (9): e1003212 (2013) «Differential effect of orexin - 1 and crf - 1 antagonism on stress circuits: a fMRI study in the rat with the pharmacological stressor yohimbine» A. Gozzi, S: Lepore, E: Merlo Pich, and A. Bifone Neuropsychopharmacology 38 (11): 2120 - 2130 (2013) «Water dispersal and functionalization of hydrophobic iron oxide nanoparticles with lipid - modified poly (amidoamine) dendrimers» A. Boni, L. Albertazzi, C. Innocenti, M. Gemmi, and A. Bifone.

Studying heparanase - a key enzyme in the development and metastasis of human cancers — scientists unveiled new fluorescent imaging agents that detect enzyme activity in healthy and diseased tissues.

Gadolinium is used as a contrast agent to improve the visibility of internal organs in magnetic resonance imaging (MRI).

November 12, 2017 - The nano - agents developed by the Singapore research team are capable of tracking down and locking onto diseased tissues in the body such as cancerous cells, sending back near - infrared signals which can be received and interpreted by a standard imaging...