Sentences with phrase «imaging probe fluorocoxib»

Vanderbilt scientist Jashim Uddin, Ph.D., and colleagues now demonstrate that the molecular imaging probe fluorocoxib A detects its target — the inflammatory enzyme COX - 2 — in a mouse model of neovascular AMD.

The title of her research presentation was: A Novel Imaging Probe for the Detection of Subclinical Bacterial Infections Involving Cardiac Devices.

In order to overcome these problems, Dr. Kizaka - Kondoh and his colleagues at Tokyo Institute of Technology developed a novel, highly - specific, functional imaging probe that can detect hypoxic tumours with HIF activity, which is a hallmark of malignancy and poor prognosis.

Publication: A novel injectable BRET - based in vivo imaging probe for detecting the activity of hypoxia - inducible factor regulated by the ubiquitin - proteasome system.

Nolting DD, Nickels ML, Guo N, Pham W. Molecular Imaging Probe Development: A Chemistry Perspective.

The new multimodal imaging probe uses an ultrafast laser to create nonlinear optical effects in tissue that can reveal cancer and other diseases.

We demonstrate that the electron beam, simultaneously acting as an imaging probe and a source of energy to drive chemical transformations, offers a new tool for studying the chemical reactions of individual molecules with atomic resolution, which is vital for the discovery of new reaction mechanisms and more efficient future synthesis.»

«Our ultimate goal is to develop an endoscopic photoacoustic imaging probe scanning the cervical canal, which would be a quicker, cheaper and non-invasive method for the diagnosis of cervical cancer,» Xiao said.

«We synthesized an imaging probe that stays dark in normal tissues but switches on like a light bulb when it reaches solid tumors.

«And molecular imaging methods face some particularly challenging hurdles such as the need to deliver the short - lived imaging probes to centers performing the imaging.»

Meguro, Japan (Scicasts)- Tumour detection using targeted fluorescent imaging probes is a promising technology that takes advantage of specific molecular events occurring in cancer tissues.

A team led by Shawn Chen of the National Institute of Biomedical Imaging and Bioengineering at the National Institutes of Health says that it has now designed a new nanocomplex containing multiple mRNA imaging probes that can retrieve spatial and temporal information from different mRNA sequences.

While my initial interest lay in the chemico - physical properties of MR imaging probes, I became increasingly involved in their application to functional MRI (fMRI), a method to map hemodynamic responses in the brain as a surrogate for changes in the underlying neuronal activity.

Not exact matches

Understanding the details of those processes «is going to require both careful analysis from Parker Solar Probe and also new, better imaging instruments.»

The new technique for functional imaging allows probing of regions on the order of billionths of meters, or nanometers, to characterize a sample's surface hills and valleys, its elasticity (or «bounciness») throughout deeper layers, and its chemical composition.

Juan Carlos Cuevas at the Autonomous University of Madrid in Spain and his colleagues modified a scanning tunnelling microscope — which allows the manipulation and imaging of atoms — to trap a ring of benzene between the probing tip of the microscope and a flat gold surface.

As it drifted down, the probe pointed infrared imaging instruments at the sun.

In graduate school Cranford first used high - tech medical imaging to probe the anatomy of a mammal — in that case a dolphin's head.

During imaging studies probing the causes of addiction, the insula often was activated when drug abusers were shown movies of others taking drugs or shown pictures of cocaine, heroin or nicotine.

The imaging technique's high resolution of soft nanoscale structures makes it possible to probe collagen samples, providing insights for improved designs of artificial skin or tissue.

Making fusion neutrons efficiently, at a small scale, could lead to advances in neutron - based imaging, and neutron probes to gain insight on the structure and properties of materials.

«Using the probe's imaging function during experiments, our medical collaborators would be able to see deep inside the brain of a living organism and guide the placement of the probe to the right brain region.»

FDG - PET, one of the only molecular imaging techniques routinely used in oncology, employs a glucose - like probe, FDG, with a radioactive isotope of fluorine attached as a beacon.

«These pictures have told us that comet nuclei are far more complex than we ever imagined,» says Laurence Soderblom of the U.S. Geological Survey, leader of the probe's imaging team.

Doctors currently rely on external ultrasound probes combined with pre-operative imaging scans to visualise soft tissue and organs during keyhole procedures as the miniature surgical instruments used do not support internal ultrasound imaging.

A clinical ultrasound imaging device (General Electric LOGIQe) was used, with the ultrasound probe applied at the scalp overlying the brain's temporal and frontal cortex (visible on the imaging screen).

Imaging atomic - scale electron - lattice interactions: A laser pulse (red beam coming from right) gives electrons in a manganese oxide a «kick» of energy while a high - energy electron beam (blue) probes the atomic structure.

The assessments, from exercise stress tests to brain magnetic resonance imaging tests, will probe the biological and clinical characteristics of the disease — for which there is not even a broadly agreed - upon definition.

To find out more about what keeps us up at night, Hirsch and her team use fMRI (functional magnetic resonance imaging) to probe how our brains are wired.

The USAMRIID team therefore set out to evaluate the ability and sensitivity of PET imaging, using a probe called [18F] DPA - 714 to detect and quantify neuroinflammation in Zika virus - infected mice.

Another potential use for this material, besides photovoltaics, is that in microscopy or imaging, researchers often need to «label» a protein or other feature with a nanoparticle «probe» to make it light up so it is easier to see and study.

The fluorescence label on the probe also allows it to be detected via high - resolution imaging techniques in tissues and organs at depths of up to one millimeter, which enables researchers to effectively monitor the in vivo enzymatic activities of MAO - B in living systems.

Now an international consortium of researchers has probed the machine's corroded fragments with sophisticated x-ray and light imaging tools to uncover the true sophistication of this geared wonder.

The method developed in this research can be used to detect cesium carbonate particles at high resolution (micrometer - level) by using a fluorescent probe called «Cesium Green,» which also enables intracellular imaging of cesium distribution.

In the mice with cancer, the probes enabled detailed, 3 - D ultrasound imaging of hypoxic tumors.

In this project — «PROBE: PROton Beam Extension for Imaging and Therapy» project — a prototype will be built of a novel high - frequency linac that can boost the energy of protons from the 250 Mega-electron volts (MeV) available from conventional medical cyclotrons to 350 MeV, sufficient for imaging all paImaging and Therapy» project — a prototype will be built of a novel high - frequency linac that can boost the energy of protons from the 250 Mega-electron volts (MeV) available from conventional medical cyclotrons to 350 MeV, sufficient for imaging all paimaging all patients.

In this case, facial probe imagery acquired in one modality is matched against a gallery database acquired using a different imaging modality.»

Advances in molecular biology, organic chemistry, and materials science have recently created several new classes of fluorescent probes for imaging in cell biology.

These probes pave the way for the easier and higher quality imaging of cells, offering many scientific and medical advantages.

This image of a growing crystal demonstrates the resolving power of scanning probe microscopy, a newly - emerging method of surface imaging.

Publishing in Nature Methods, EPFL scientists have exploited the properties of a new fluorescent molecule, also developed at EPFL, to generate two powerful probes for the imaging of the cytoskeleton with unprecedented resolution.

Only one imaging study (conducted by Takahashi's group in Japan) has probed the neural basis of envy.

This special imaging fiber allowed the researchers to keep all moving parts and electric power outside of the probe head, making the probe easy and safe to use in the body.

In an important step toward endoscopic diagnosis of cancer, researchers have developed a handheld fiber optic probe that can be used to perform multiple nonlinear imaging techniques without the need for tissue staining.

If miniaturized further, the probe could easily be integrated into an endoscope for nonlinear multimodal imaging inside the body.

With the new probe, imaging techniques that previously required bulky table - top instruments can be performed with a handheld device measuring only 8 millimeters in diameter, about the same diameter as a ballpoint pen.

The researchers demonstrated the unique capabilities of the multicore imaging fiber by moving one end of the probe across a sample and transferring the acquired images to the other end.

High - resolution thermal imaging of Jupiter by the COoled Mid-Infrared Camera and Spectrometer (COMICS) mounted on the Subaru Telescope on Maunakea is providing information that extends and enhances the information that the Juno mission is gathering in its unprecedented mission to probe that planet's interior and deep atmospheric structure together with details of the magnetosphere and its auroral interactions with the planet.

Ghez has been able to enhance her research by using adaptive optics imaging technology that compensates for the blurring effects of the Earth's atmosphere by using a laser to probe the atmosphere, resulting in much sharper images.

Then the probes and the interactions they flag are subjected to scrutiny at EMSL, the DOE's Environmental Molecular Sciences Laboratory on the PNNL campus, where instruments detect redox activity through various means, such as through fluorescent imaging and mass spectrometry.