Sentences with phrase «imaging probes»
"Imaging probes" refer to substances or agents used to detect and visualize specific structures or processes in the body. These probes are often used for medical purposes to help doctors and researchers see inside the body and identify diseases or abnormalities. Full definition
Among these methods include validation of imaging probes for novel applications, as well as high - throughput small - molecule discovery to develop novel imaging compounds.
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Jun. 17, 2015 — A new imaging probe developed by Vanderbilt investigators enhances tumor visibility and has broad applications in diagnosing and monitoring patients with cancer.
The new multimodal imaging probe uses an ultrafast laser to create nonlinear optical effects in tissue that can reveal cancer and other diseases.
Nolting DD, Nickels ML, Guo N, Pham W. Molecular Imaging Probe Development: A Chemistry Perspective.
«And molecular imaging methods face some particularly challenging hurdles such as the need to deliver the short - lived imaging probes to centers performing the imaging.»
«Our ultimate goal is to develop an endoscopic photoacoustic imaging probe scanning the cervical canal, which would be a quicker, cheaper and non-invasive method for the diagnosis of cervical cancer,» Xiao said.
Meguro, Japan (Scicasts)- Tumour detection using targeted fluorescent imaging probes is a promising technology that takes advantage of specific molecular events occurring in cancer tissues.
Publication: A novel injectable BRET - based in vivo imaging probe for detecting the activity of hypoxia - inducible factor regulated by the ubiquitin - proteasome system.
In order to overcome these problems, Dr. Kizaka - Kondoh and his colleagues at Tokyo Institute of Technology developed a novel, highly - specific, functional imaging probe that can detect hypoxic tumours with HIF activity, which is a hallmark of malignancy and poor prognosis.
Because the function of many important biological factors is controlled by the UPS, this study also offers a general strategy in the design of highly - specific injectable imaging probes for monitoring aberrant activity of the UPS - regulated factors both in cultured cells and whole organisms, thus opening new avenues in molecular imaging.
A team led by Shawn Chen of the National Institute of Biomedical Imaging and Bioengineering at the National Institutes of Health says that it has now designed a new nanocomplex containing multiple mRNA imaging probes that can retrieve spatial and temporal information from different mRNA sequences.
Vanderbilt scientist Jashim Uddin, Ph.D., and colleagues now demonstrate that the molecular imaging probe fluorocoxib A detects its target — the inflammatory enzyme COX - 2 — in a mouse model of neovascular AMD.
The handheld multimodal imaging probe can simultaneously acquire several types of images: coherent anti-stokes Raman scattering, second harmonic generation and two - photon excited auto - fluorescence.
He then pursued a postdoctoral fellowship at Memorial Sloan Kettering Cancer Center in 2015, where he developed cancer immunotherapies for solid tumors and imaging probes for nuclear oncological imaging.
«We synthesized an imaging probe that stays dark in normal tissues but switches on like a light bulb when it reaches solid tumors.
We demonstrate that the electron beam, simultaneously acting as an imaging probe and a source of energy to drive chemical transformations, offers a new tool for studying the chemical reactions of individual molecules with atomic resolution, which is vital for the discovery of new reaction mechanisms and more efficient future synthesis.»
Researchers at the U.S. Department of Energy's Ames Laboratory have developed germanium nanoparticles with improved photoluminescence, making them potentially better materials for solar cells and imaging probes.
Technologies and approaches appropriate for study, development and enhancement under this [announcement] include hardware (e.g., instruments, devices, etc.), software (e.g., computational algorithms, informatics tools, etc.), and wetware (e.g., imaging probes, genetic tools, etc.) that would be used to study the brain or behavior in basic or clinical research (or for clinical use).»
Oct. 12, 2016 — An imaging probe developed at Vanderbilt detects retinal inflammation early and may allow therapeutic intervention to prevent blindness.
Schaub, F.X., et al. (3) designed two imaging probes.