Sentences with phrase «imatinib mesylate»

«Although TKIs such as the first - generation TKI imatinib mesylate (IM) and the second - generation TKIs dasatinib and nilotinib have markedly improved the prognosis of patients with chronic phase CML, a cure remains elusive.

The drug imatinib mesylate (Gleevec) is shown to be effective against chronic myelogenous leukemia (CML).

[12] It was marketed in 2001 by Novartis as imatinib mesylate (Gleevec in the US, Glivec in Europe).

Phase II, open - label, single - arm trial of imatinib mesylate in patients with metastatic melanoma harboring c - Kit mutation or amplification.

Effects of the protein kinase inhibitor, imatinib mesylate, on epithelial / mesenchymal phenotypes: implications for treatment of fibrotic diseases.

Medical treatment usually involves either imatinib mesylate (Gleevec ®) sunitinib (Sutent ®), or investigational drugs through clinical trials.