A controlled laboratory study was conducted to evaluate the efficacy of four commercial products administered as a single treatment for the prevention of heartworm disease caused by Dirofilaria
immitis in dogs.
Warnings and reports about pets infected with Dirofilaria
immitis in the United States are not unusual.
The full study, A. Ray Dillon, et al., «Effect of pre-cardiac and adult stages of Dirofilaria
immitis in pulmonary disease of cats: CBC, bronchial lavage cytology, serology, radiographs, CT images, bronchial reactivity, and histopathology.»
The study, «Effect of pre-cardiac and adult stages of Dirofilaria
immitis in pulmonary disease of cats: CBC, bronchial lavage cytology, serology, radiographs, CT images, bronchial reactivity, and histopathology,» demonstrated that pre-cardiac stages of D. immitis - induced chronic lung disease was prevented by the administration of REVOLUTION one month prior to infection.
About the Study A controlled, masked research study was conducted to define the initial inflammatory response and lung damage associated with the death of precordia stages of D.
immitis in cats as compared to adult heartworm infections in normal cats.
Not exact matches
Other mosquito species can transmit Dirofilaria
immitis, the nematode that produces heartworm disease; however, A. notoscriptus has the highest vectorial capacity and tends to have the highest rates of dog heartworm
in the field.
Activity of pulmonary intravascular macrophages
in cats and dogs with and without adult Dirofilaria
immitis.
Other parasites that can cause verminous myelitis include Spirocerca lupi, Angiostrongylus spp., Dirofilaria
immitis, Strongyloides spp. and Halicephalobus spp., according to an article published
in the September 2009 issue of the «Journal of Veterinary Diagnostic Investigation.»
Caused by infestation of the parasite Dirofilaria
immitis, heartworms are transmitted by mosquitoes and can affect any dog anywhere
in the US.
Feline heartworm (Dirofilaria
immitis) infection: a statistical elaboration of the duration of the infection and life expectancy
in asymptomatic cats.
In short, Dirofilaria
immitis invades the heart, lungs and nearby vessels of the dog, eventually leading to death.
«Current canine guidelines for the prevention, diagnosis, and management of heartworm (Dirofilaria
immitis) infection
in dogs.»
Dirofilaria
immitis is particular specie of heart worm and is considered to be the cause of heart worm disease
in dogs.
Heartworms Dirofilaria
immitis, spread through mosquito bites and grow
in the upper chambers of the heart, causing lack of energy, a moist cough, and heart failure.
Following American Heartworm Society and Companion Animal Parasite Council guidelines, dogs that have stabilized Class 1, 2 or 3 heartworm disease should receive three doses of DIROBAN.3 - 4 Laboratory and clinical field trials show that treatment with DIROBAN results
in the reduction and / or clearance of D.
immitis infection.5 DIROBAN is now available to U.S. veterinarians.
McCall JW, Arther R, Davis W, Settje T. Safety and efficacy of 10 % imidacloprid + 2.5 % moxidectin for the treatment of Dirofilaria
immitis circulating microfilariae
in experimentally infected dogs.
Effects of doxycycline on the endosymbiont Wolbachia
in Dirofilaria
immitis (Leidy, 1856)-- Naturally infected dogs.
[2] The direct smear technique allows examination of larval motion, helping
in the distinction of D.
immitis from Acanthocheilonema reconditum.
Heartworm is a parasitic roundworm (Dirofilaria
immitis) found
in nearly all locations where mosquitos are present.
Tri-Heart ® Plus is an oral antiparasitic medication for use
in dogs indicated for prevention of heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilarfa
immitis) for a month (30 days) after infection and for the treatment and control of ascarids (Toxocara canis, Toxocara leonina) and hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense).
«Presently, there is no evidence that reduced susceptibility to macrocyclic lactones is a widespread phenomenon
in the D.
immitis population or will ever become one,» the company stated by email to the VIN News Service.
«Regardless of which product was used, whether it was oral, topical or injected, protection against some Dirofilaria
immitis isolates from the Mississippi River Valley was less than 100 percent for all active ingredients included
in the ML class,» he said.
Dirofilaria
immitis exposure status
in client - owned cats with or without lower airway / lung - associated signs: case - control study
in a canine heartworm - endemic area.
It is approved by the FDA
in the prevention of heartworm infections
in dogs especially those brought about by Dirofilaria
immitis as well as
in the control and elimination of other nematode genera such as hookworms and whipworms.
The progression of the condition is quite slow, however, as Dirofilaria
immitis has been known to be present
in dogs for as long as 7 years.
According to the American Heartworm Society (AHS), «Heartworm disease is one of the major health problems of dogs
in the United States and throughout the temperate and tropical areas of the world... The disease develops when a pet becomes infected with parasites called Dirofilaria
immitis that are transmitted through the bite of an infected mosquito.
Pulmonary arterial disease
in cats seropositive for Dirofilaria
immitis but lacking adult heartworms
in the heart and lungs.
Caused by the parasite «Dirofilaria
immitis», heartworm disease is actually a type of roundworm that settles inside the blood vessels
in the lungs as well as inside the heart.
Heartworm, Dirofilaria
immitis, is a blood parasite that lives
in the blood stream of dogs and cats.
In the majority of cases, these D.
immitis antigen tests meet practitioners» needs for speed and accuracy.
The mosquito - borne parasite Dirofilaria
immitis is known to infect multiple species, including dogs, cats, ferrets, wolves, coyotes, foxes, sea lions, and even humans.1 Canids, including dogs, are the definitive hosts, while cats are viewed as aberrant or atypical hosts.1 Unlike dogs,
in North and South America, D
immitis is the only filarial disease that infects cats.2
In areas where dogs are exposed to mosquitoes that carry D
immitis, so are cats.
In a recent study from another non-endemic area (Munchen, Germany), among 72 imported or travelling dogs with D. immitis microfilariae in the blood, and examined between 1993 - 96, 27 (37.5 %) resulted sero - negative with the ELISA test (Zahler et al., 1997), apparently confirming the results here reporte
In a recent study from another non-endemic area (Munchen, Germany), among 72 imported or travelling dogs with D.
immitis microfilariae
in the blood, and examined between 1993 - 96, 27 (37.5 %) resulted sero - negative with the ELISA test (Zahler et al., 1997), apparently confirming the results here reporte
in the blood, and examined between 1993 - 96, 27 (37.5 %) resulted sero - negative with the ELISA test (Zahler et al., 1997), apparently confirming the results here reported.
Heartworm disease (HWD), caused by the mosquito - borne nematode Dirofilaria
immitis, is endemic
in most areas of the United States, including urban areas where most of the U.S. population (about 80 %) lives.
In the non-endemic area of Fermo (Ascoli Piceno province), concentration test results were similar and microfilaraemia due to D. immitis (1 to 8 per sample) was present in the total number of dogs with clinical manifestations (Fig. 1,2,4), without significant quantitative differences in comparison with the results coming from the endemic are
In the non-endemic area of Fermo (Ascoli Piceno province), concentration test results were similar and microfilaraemia due to D.
immitis (1 to 8 per sample) was present
in the total number of dogs with clinical manifestations (Fig. 1,2,4), without significant quantitative differences in comparison with the results coming from the endemic are
in the total number of dogs with clinical manifestations (Fig. 1,2,4), without significant quantitative differences
in comparison with the results coming from the endemic are
in comparison with the results coming from the endemic area.
Detection of D.
immitis microfilariae
in a seronegative dog, can occur when only a single gravid female lives
in the pulmonary arteries of the host.
1) Dirofilaria
immitis microfilaria (x10, filtration test)
in the blood of a seronegative symptomatic dog from the non-endemic area of Fermo (Marche, Italy)
As a matter of fact, none of seven dogs from a non-endemic area
in Central Italy (Fermo, Marche), with D.
immitis microfilariae (fig. 1,2,4)
in the blood and patent disease, proved seropositive with two antigen tests (PetChek and Wittness).
Geographic distribution of D.
immitis and D. repens coincides (Fig. 5)
in many areas of South Europe (Genchi et al., 1995; Rossi et al., 1996) and cross reactivity between the two nematodes is regularly shown by different tests, producing false seropositive results (Schrey, 1996).
Heartworm disease was first reported
in cats
in Brazil
in 1921, yet some still believe that cats can not be infected with D
immitis.2 A 2007 study demonstrated that when dogs that were not administered a heartworm preventive were artificially infected with 100 L3 larvae, approximately 75 % of the larvae developed into adult heartworms
in every dog.
4) Detail of the caudal end of a Dirofilaria
immitis microfilaria (x40, filtration test), from a seronegative and symptomatic dog living
in non-endemic area (Fermo, Marche, Italy).
2) Dirofilaria
immitis microfilaria (x4)
in a fresh blood smear from a seronegative dog, living
in non-endemic area (Fermo, Italy).
At the present time, heartworm disease caused by the filarial helminth Dirofilaria
immitis is not endemic
in most of the European countries (Greeve et al., 1983; Schrey, 1996).
A heartworm is a parasitic worm (Dirofilaria
immitis) that lives
in the heart and pulmonary arteries of an infected animal.
In summary, serological tests for heartworm disease are frequently negative in non-endemic areas because of the low number of D. immitis adults in the pulmonary arteries of the hos
In summary, serological tests for heartworm disease are frequently negative
in non-endemic areas because of the low number of D. immitis adults in the pulmonary arteries of the hos
in non-endemic areas because of the low number of D.
immitis adults
in the pulmonary arteries of the hos
in the pulmonary arteries of the host.
When fixed using 2 per cent formalin, microfilariae of D.
immitis are 262 - 338 mm
in length and 4 - 6,2 mm
in width (Schrey, 1996), distinguishing them from the non-pathogenic filarial larvae of A. reconditum which are shorter and thinner (241 - 287 mm x 3,8 - 5 mm).
At necropsy, all 8 dogs
in the nontreated group were infected with adult D.
immitis (34 - 70 worms / dog, geometric mean (GM) = 51.6 worms / dog).
One or more adult D.
immitis and / or worm fragments were recovered from 7 of 8 of the dogs each
in Groups 1 - 3 (87.5 % were heartworm positive).
«Heart worm
in dogs is caused by bites from infected mosquitoes that transmit the heartworm (Dirofilaria
immitis) into the dog.
Dirofilaria
immitis is a roundworm parasite that lives
in the blood vessels and the heart.