Sentences with phrase «immune attack against»

The GAD enzyme may cross-react with gluten so that eating gluten can stimulate an immune attack against GAD.

I believe what happens is antibodies against food happen to be shaped so that they also bind to bodily tissues, launching a painful or disabling immune attack against your joints, your digestive system, or even your nervous system.

MD Anderson has more than 160 clinical trials open testing drugs and cellular therapies that stimulate and support immune attack against many different types of cancer.

In some cases, the transplanted marrow launches an immune attack against the host's cells, a potentially lethal condition called graft - versus - host disease.

Orchestrating a successful immune attack against tumors has proven difficult so far, but a new study from MIT suggests that such therapies could be improved by simultaneously activating both arms of the immune system.

«We're taking advantage of the fact that patients mount an immune attack against this viral protein,» said Morrissey.

The immune system can, for example, dispatch «regulatory» cells that suppress immune attacks against self.

This is important: if the fetus had an ability to generate antibodies and mount an immune response, it might generate immune attacks against the mother leading to miscarriage.

Not exact matches

This is where the immune system — the body's defence against infection — mistakenly attacks healthy tissue.

Previous research has suggested that antibodies — immune system proteins that can attack viruses — in a mother might be less effective against certain genetic variants of HIV - 1 in her body, thereby allowing for transmission of resistant viruses to her infant at delivery.

On its own, this immune response had no immediate effect in the fight against the utilized breast tumors, but in combination with the ADC it proved itself effective in attacking cancer cells in mice, resulting in the complete cure of the majority of mice receiving the combination therapy.

TECHNICAL DIFFICULTIES Scientists doing gene editing need to be aware of potential immune system attacks against a DNA - cutting protein.

Antibodies and T cells against the protein could cause the immune system to attack cells carrying it, making gene therapy ineffective.

Immunotherapy is an emerging field in the global fight against cancer, even though scientists and clinicians have been working for decades to find ways to help the body's immune system detect and attack cancerous cells.

Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body; in other words, the body attacks its own cells.

The new «trivalent» vaccine induces antibodies against three different parts of the virus, including two components that normally help HSV2 evade immune attack.

The researchers studied two types of cells called effector T cells, which activate the immune system to defend our body against different pathogens, and regulatory T cells, which help control the immune system and prevent it from attacking healthy parts of its environment.

Wherever the answer lies, the insights could help in the development of vaccines against other diseases that, like HIV, don't easily succumb to immune attack and that kill millions of people.

The capsule protects the donator's cells against attacks of the immune system but, passes the hormones by semi-permeable walls into the body of the receiver.

Lupus, or systemic lupus erythematosus, is a progressive, degenerative disease in which the immune system turns against itself, attacking a person's healthy tissue, cells and organs.

Healthy skin is protected against microbial attack by different kinds of immune cell, including T cells.

One promising strategy in the fight against cancer is to use the body's own immune system to remove tumor cells, but due to a phenomenon called immune tolerance, the immune system has a difficult time identifying which cells to attack.

This form of interference with bacterial gene regulation is also of pharmaceutical interest as it is known that pathogenic bacteria can protect themselves against attack by the immune system and the effect of antibiotics by forming biofilms, for instance on the epithelium of the respiratory system.

The answer is complicated, he adds, but much of it involves a delicate balancing act among elements of the immune system: while immunity protects us against disease, an overly aggressive immune response may trigger dangerous, even life - threatening, autoimmune reactions in which the body attacks itself.

Engineered with special tumor - recognition molecules, Listeria prods the immune system into action, marshaling an attack against tumors that the body might otherwise be unable to combat.

In addition to being the first line of defense against pathogenic attack, the immune system seeks out aberrant cells within the body that may become cancerous.

The intervention, he says, essentially trains the immune system to recognize and attack the tumor, and to protect against additional tumor formation — a significant issue in colon cancer.

Research is also underway to understand whether it can elicit a response against tumors that typically don't provoke an immune attack.

Instead of working through antibody - mediated immunity, Liang says successful prophylactic vaccines against the virus might have to work through cell - mediated immunity, which means immune cells are taught to attack infected cells.

Kwak has developed anti-cancer therapeutic vaccines to spark an immune system attack against tumors, but their effectiveness has been hindered by factors such as MDSCs that stifle immune response.

Vitamin D is thought to protect against such attacks by boosting immune responses to respiratory viruses and dampening down harmful airway inflammation.

New research out of the University of Michigan supports combining two approaches to fight back against gliomas: attacking the tumor with gene therapy while enhancing the immune system's ability to fight it, too.

Instead of protecting the tumor, the TAMs now signaled the presence of the tumor to the immune system, triggering attacks against it — and did so very efficiently.

The immune system protects us from scores of invaders, but it can also turn against us when white blood cells called autoimmune T cells attack the body's own tissue.

* In type 1 diabetes, the insulin - producing cells in the Langerhans islets of the pancreas are destroyed because they are attacked by the body's immune system (formation of islet autoantibodies against structures of the beta cells).

The hallmark of vertebrate immune systems is their ability to «remember» an infection and mount specific attacks against microbial invaders the next time they come knocking.

Immunity is key to long - term responses Knowing that the immune system is capable of recognizing distinctive features of cancer cells and launching a T cell attack against those tumor antigens, and that checkpoint blockade removes a roadblock to that attack, it's logical that these drugs should work against many tumor types.

They can also induce responses against normal tissue antigens, leading the immune system to attack normal tissues and cause toxicity in a subset of patients.

The drugs, ipilimumab (Yervoy ®) and nivolumab (Opdivo ®), made by Bristol - Myers Squibb (BMS), are two immune checkpoint inhibitors that «release the brakes» on the immune system, allowing it to mount a stronger and more effective attack against cancer.

The idea behind a vaccine is simple: by exposing the immune system to a tell - tale piece of pathogen, the immune system is alerted to danger and mounts a specific attack against invaders that have this trait.

Recent studies have shown that pathogenic bacteria possess an immune defense system against predators, and particularly against attacks by viruses (bacteriophages).

Additionally, mesenchymal stem cells induce the production of T regulatory cells, a type of immune cell whose function is to protect the body against immunological self - attack.

Cancer vaccines are designed to stimulate an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

Another approach, still early in clinical development, uses antibodies to vaccinate patients against their own tumours, pushing their immune system to attack the cancer cells.

In different contexts, viruses appear capable of attacking tumors in a number of different ways — by directly infecting them, by releasing tumor proteins that trigger a broad immune response against the cancer, and by damaging the blood supply tumors need to survive.

The women's immune systems — in mounting a response against the synaptic receptors present in the ovarian growths — inadvertently attacked a receptor in the brain called N - methyl - D - aspartate receptor, or NMDAR.

Therapeutic vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

An important area of research focus for NIAID is the immune system, the complex network of cells, tissues, and organs that work together to defend the body against attacks by foreign invaders such as bacteria, viruses, parasites, and fungi.

LA JOLLA, CA — When the body is under attack from pathogens, the immune system marshals a diverse collection of immune cells to work together in a tightly orchestrated process and defend the host against the intruders.

If a patient is injected with stem cells taken from a donated embryo, his or her immune system may see the cells as foreign invaders and launch an attack against them.