Not exact matches
Kristian Doyle, assistant professor of immunobiology and neurology at the University of Arizona College of Medicine in Tucson, uses
biomarkers to
study how the
immune system deals with dead brain tissue after a stroke.
She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the
study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to
study methods can cure the genetic defect that causes thalassemia through genetic engineering; she
studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the
immune response against cancer and infectious diseases; she investigates about the identification and development of
biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.
In the next year, members of the Dream Team will continue to
study the tumor microenvironment before and after checkpoint blockade, to develop algorithms to identify and predict the best antigens on cancer cells that can be used for cancer immunotherapies, to analyze tumor tissues and blood for
biomarkers that will help in selecting patients who will benefit, and identifying the best approaches to increase the strength of
immune cells for adoptive cell therapy.
PHILADELPHIA --(April 18, 2018)-- An international team focused on HIV cure research spearheaded by The Wistar Institute in collaboration with the University of Pennsylvania and Vall d'Hebron Research Institute (VHIR) in Barcelona, Spain, established that the CD32 molecule is not a preferential
biomarker to identify HIV silent reservoirs within the
immune system of patients undergoing antiretroviral therapy (ART), as proposed by a recent landmark
study.
Comprehensive
studies of changes in the resident intestinal microbiota, host metabolism and
immune system reactivity in T1D patients and cohorts at risk of T1D, as well as the correlation with clinical data, anti-islet antigen antibodies and HLA genotypes will enable identification of novel
biomarkers and biosignatures, and insights into the pathophysiology of the onset of T1D.
The
study, led by UNC Lineberger researcher Benjamin Vincent, MD, could lay the foundation for the discovery of
biomarkers to determine which patients might respond to certain
immune - stimulating cancer treatments.