Sentences with phrase «immune cell entry»

«The control of immune cell entry into the joint represents a major point at which new therapies could be developed to reduce the symptoms of inflammatory arthritis,» says Luster, who is the Harrison Professor of Medicine at Harvard Medical School.

Not exact matches

CRAC channels control the entry of calcium into immune and other cell types, and calcium is an important intracellular signaling molecule that modulates cytokine production and the immune response.

Because your gut is often the first entry point for pathogens, you'll want to ensure that you have enough friendly gut flora (the good bugs that are allies for immune cells) to prevent pathogens and infections from being absorbed through the gut lining.

Only viruses that have mutated escape mechanisms from immune pressures are able to survive, but the mutations come at the cost of other aspects of viral fitness, perhaps inhibiting entry into cells or integration into cell DNA.

Last year, researchers at NIAID and elsewhere solved a decade - long mystery when they found that HIV uses a second set of proteins to gain entry into immune cells.

Except, that is, in the brain, where the blood - brain barrier bars both foreign bodies and immune cells from entry.

«Making the movements of HIV visible so that we can follow, in real time, how surface proteins on the virus behave will hopefully tell us what we need to know to prevent fusion with human cells — if you can prevent viral entry of HIV into immune cells, you have won,» says Dr. Blanchard, who is also associate director of Weill Cornell's chemical biology program.

The researchers have shown for the first time that antiviral proteins (the IFITM proteins) produced through the natural immune response block the entry of the hepatitis C virus into the cell.

In addition, the strain isolated from lions and hyenas during the 1993/1994 epidemic had rare mutations in two viral proteins: the CDV - H protein, which binds to the host cell receptor (called SLAM CD 150) and therefore plays an important role to facilitate viral entry into host cells, and the CDV - V protein, which enables the virus to manipulate the innate immune response of the host.

Hemagglutinin (HA) and neuraminidase (NA) are the two predominant viral glycoproteins found in the viral envelope, and are the primary targets of the host immune system and are key factors in the entry and exit of influenza particles from host cells.

A vaccine should tip the balance of this contest in favor of the immune system by increasing the numbers of CD4 + and CD8 + cells that are poised to swing into action if HIV gains entry to the body at some point in the future.

He has been a leader in applying molecular and genetics tools to study the immune system including specification of T lymphocyte lineages, the differentiation of inflammatory T helper cells, the role of microbiota in regulating immune responses, and the mechanisms of HIV entry and pathogenesis.

They found that Lymphotoxin β receptor, a cell surface molecule, controls the entry of T - cell progenitors to the thymus, both in a healthy state and during immune recovery following bone - marrow transplantation.