Sentences with phrase «immune cell expansion»

Not exact matches

In that paper, Weitzmann, Ofotokun, and their colleagues described bone loss similar to that observed in humans following the reconstitution of the T cell population in immune - compromised mice (similar to T - cell expansion following ART).

First author of the paper, Dr Christian Schwartz, a European Molecular Biology Organization Long Term Fellow in Professor Fallon's group, added: «It is fascinating that a small cell population such as the ILC2s can regulate the expansion of Th2 cells and thereby shape the whole outcome of an immune response — be it beneficial in case of parasitic infections, or detrimental as in the case of allergic responses.»

Even though STAT3 activity drives the expansion of MDSCs and is involved in immune responses mediated by the cells, they found that high levels of STAT3 activity actually prevent the differentiation of MDSCs to macrophages.

Tryptophan depletion results in the inhibition of effector T cells and kynurenine accumulation results in the expansion of immune - suppressant regulatory T cells.

The strict limit in proliferative potential of normal human somatic cells - a process known as replicative senescence - is highly relevant to the immune system, because clonal expansion is fundamental to adaptive immunity.

The scientists» studies also showed that AIM2 played a role independent of its immune role, in suppressing abnormal expansion of intestinal stem cell populations.

First, when GLA is accompanied by a tumor antigen and injected into a patient, the combination is taken up by the DCs and leads to the production and expansion of immune cells called CD4 helper T cells.

It also controlled the size of the T cell expansion and the function of these immune cells against the infection.

Revealed that the loss of the human leukocyte antigen (HLA) locus in lung cancers is a way these tumors evade the immune system and allow mutation expansion and branched evolution within tumor cells

The macrophages release cytokines that can activate more innate immune cells, readying them for attack on viruses or cancer cells, or they can activate the adaptive arm of immunity, priming it for clonal expansion.

These cells, along with dendritic cells, recognize the incoming undigested food particles, toxic agents, and bacterial components as foreign invaders, and present them to cells of the adaptive immune system called T and B lymphocytes, leading to clonal expansion (proliferation or multiplication of specific subsets of T and B cells) and recruitment of more pro-inflammatory immune cells to the gut through a process called leukocyte homing.