Sentences with phrase «immune cell recruitment»

(A) Cellular and molecular mechanisms of immune cell recruitment and activation in inflammatory and metabolic disease.

«Scientists find potential mechanism for deadly, sepsis - induced secondary infection: Sepsis disrupts immune cell recruitment to infected skin in mice.»

Not exact matches

Current thinking regarding type III hypersensitivity is that immune cells within tissues sense the presence of these immune complexes (ICs) through specific receptor molecules and release inflammatory factors called cytokines that activate the endothelial cells lining adjacent blood vessels to promote the recruitment of neutrophils.

As revealed in the Nature paper, this repetitive cycle of abortive infection, cell death, inflammation and recruitment of additional CD4 T cells to the infection «hot zone» ultimately destroys the immune system and causes AIDS.

Jessica Jang, the lead author of the research paper and a third - year UCR graduate student in microbiology, explained that resistin regulates the recruitment of innate immune cells called monocytes to the site of infection to produce inflammatory cytokines (small proteins that are important in cell signaling).

Antibodies stimulate the recruitment of additional immune cells that help to activate T cells; the vaccine stimulates proliferation of T cells that can attack the tumor; IL - 2 helps the T cell population to expand quickly; and the anti-PD1 molecule helps T cells stay active longer.

Second, NK cells churn out many different forms of signaling proteins, which can promote or suppress inflammation by aiding in recruitment and activation of other immune cells.

«We're very interested in following up by finding more direct proof that if you block the recruitment of immune cells to tumors, you can reverse this phenomenon in these animals with endothelial cell insulin resistance,» Rask - Madsen says.

Recent findings suggest that tumor associated stroma is another important regulator of tumor growth and progression which may also modulate the recruitment, activation status and retention of immune cells in the tumor microenvironment.

Results from previous studies have demonstrated that blocking just one of the steps can significantly reduce neutrophil recruitment... When there is a site of inflammation in the body, the blood flow increases because the blood transports immune cells to the site to promote healing.

The immune system becomes overwhelmed as the ongoing stimulus results in more cell recruitment, increased inflammation, and changes to cells.

These cells, along with dendritic cells, recognize the incoming undigested food particles, toxic agents, and bacterial components as foreign invaders, and present them to cells of the adaptive immune system called T and B lymphocytes, leading to clonal expansion (proliferation or multiplication of specific subsets of T and B cells) and recruitment of more pro-inflammatory immune cells to the gut through a process called leukocyte homing.

The bottom line is that stress shuts down either the recruitment or the function of those immune cells needed to fight infection.