Sentences with phrase «immune cell subtypes»
She observed that the repertoire of immune cell subtypes differed between normal and engineered mice, and furthermore, that T cells of engineered mice fed a «western» (fatty) diet produced inordinately high levels of pro-inflammatory cytokines.
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More recent work by Aggarwal and Pittenger 82 supported the feasibility of MSC - transplantation showing that MSC altered the phenotypes of specific immune cell subtypes thereby creating a tolerogenic environment.
«We have identified similar immune cell subtypes that are present in the human heart,» Lavine said.
«Potential to predict peanut allergy immunotherapy outcomes: Successful immunotherapy induces changes in immune cell subtypes.»
Not exact matches
«Suppressing a progenitor from creating the subtype of dendritic cells implicated in causing lupus, for example, could be an efficient way of treating autoimmune diseases while minimising the impact on the rest of the immune system.
In additional experiments, the scientists found that participants who had significant antibody responses did not necessarily also have significant immune system T cell responses to avian viruses, indicating that these two arms of immunity can be independently boosted after vaccination or infection; that individuals who reported receiving seasonal influenza vaccination had significantly higher antibodies to the avian H4, H5, H6, and H8 subtypes; and that participants with exposure to poultry had significantly higher antibody responses to the H7 subtype, but to none of the other subtypes tested.
The patients without diabetes produced autoantibodies that completely impaired the activity of a subtype of interferon known as interferon - alpha, which is produced by the immune cells and may cause inflammation.
These specific groups include T - cell subtypes (such as CD4 + CD25 + T cells), as well as a unique fraction of DCs described as semimmature DCs, all of whom were shown to possess immune - modulating properties.
Although T - cell immune activation is strongly associated with disease progression in HIV subtype B infections, this study suggests that viral replication is the primary driver of HIV disease in Uganda where subtype A, D, and D containing recombinants circulate.
Title: Infiltrating immune cells in breast cancer subtypes Date / Time: Tuesday, April 17 2018, 8:00 am - 12:00 pm CT Author: J.L. Matta et al, Ponce Health Sciences Institute and H. Lee Moffitt Cancer Center Poster # / Location: 5698 / Section 32, Board 4 Hyperlink: http://www.abstractsonline.com/pp8/#!/4562/presentation/7977 Demonstrates the value of combining PAM50 subtype distribution with tumor immune profiling to identify biologically distinct patient populations; the combination of these signatures could be applied to the development of specific immunotherapeutics.