Sentences with phrase «immune cell types at»

Understanding which cytokines are best for monitoring inflammation and immunosuppression, and knowing which are secreted by different immune cell types at each stage of maturation and activation, will provide essential insights into disease treatment options.

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Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

(borrowed from Dr Kitty) Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

In the second Cell paper, researchers collaborated with scientists at the University of Cambridge, McGill University in Canada and several UK and European institutions to explore the role that epigenetics plays in the development and function of three major human immune cell types: CD14 + monocytes, CD16 + neutrophils and naïve CD4 + T cells, from the genomes of 197 individuCell paper, researchers collaborated with scientists at the University of Cambridge, McGill University in Canada and several UK and European institutions to explore the role that epigenetics plays in the development and function of three major human immune cell types: CD14 + monocytes, CD16 + neutrophils and naïve CD4 + T cells, from the genomes of 197 individucell types: CD14 + monocytes, CD16 + neutrophils and naïve CD4 + T cells, from the genomes of 197 individuals.

Researchers at Penn State have combined the two approaches by taking biodegradable polymer nanoparticles encapsulated with cancer - fighting drugs and incorporating them into immune cells to create a smart, targeted system to attack cancers of specific types.

Antibodies derived from a type of immune cell found in unusually high numbers in HIV - infected individuals with chronically uncontrolled virus levels are less effective at neutralizing HIV than antibodies derived from a different type of immune cell more common in people without HIV, scientists report.

In type 1 diabetes, beta cells in the pancreas that make insulin — the hormone that keeps our blood glucose levels at a safe concentration — are destroyed by the immune system.

Professor Dan Davis and his team at the Manchester Collaborative Centre for Inflammation Research, working in collaboration with global healthcare company GSK, investigated how different types of immune cells communicate with each other — and how they kill cancerous or infected cells.

The new NYU Langone study revolves around the ability of immune cells to «decide» which cell types to become based on the type of invader encountered — including macrophages that arrive first at the sites of infection.

«Although right now we are focusing on developing a cancer vaccine, in the future we could be able to manipulate which type of dendritic cells or other types of immune cells are recruited to the 3D scaffold by using different kinds of cytokines released from the MSRs,» said co-lead author Aileen Li, a graduate student pursuing her Ph.D. in bioengineering at Harvard SEAS.

An international research team headed by the rheumatologist Dr Andreas Ramming at Friedrich - Alexander - Universität Erlangen - Nürnberg (FAU) has now managed to identify an immune system cell type that can be used in a targeted attempt to control the inflammatory response in arthritis patients.

In an effort to further define the importance of GATA - 3, researchers at the University of North Carolina have traced how the protein performs important functions in CD8 + T - cell type of the immune system.

In a new study published in Nature Neuroscience this week, researchers in the Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital (BWH) investigate how genetic risk factors for Alzheimer's disease may influence a key type of immune cell.

Researchers at Joslin Diabetes Center now have pinpointed a major inflammatory role for «natural killer» (NK) immune cells in abdominal fat — a type of tissue strongly implicated in insulin resistance.

Scientist at the University of Bonn and TU Munich have now discovered that type I IFN released by immune cells due to increased migration of gut bacteria into the cirrhotic liver incapacitate the immune system.

To get to the bottom of this question, researchers in the Perelman School of Medicine at the University of Pennsylvania engineered mice in which the damage caused by a mutant human TDP - 43 protein could be reversed by one type of brain immune cell.

A research team, led by Chao Cheng, Ph.D., Assistant Professor in the Department of Genetics at The Geisel School of Medicine at Dartmouth, used gene expression data from breast cancer patients to computationally infer the presence of different types of immune cells.

Her aim is to understand, at the molecular level, the mechanisms that control communication between the brain, immune system, and blood vessels — with the ultimate goal of designing new therapies that slow, stop, or reverse the progression of a wide range of neurological disorders, such as MS. Recently, Dr. Akassoglou's lab identified how microglia — a type of immune cell that acts as the brain's first line of defense — are activated when fibrinogen enters the brain or spinal cord.

Working in mice, Norbury's team used several methods to deplete different types of innate immune cells — collectively known as myeloid cells — at the three checkpoints before infecting the rodents with poxvirus.

In 1973, a research team headed by Ralph Steinman at the Rockefeller University also described a new immune cell type, which they called the dendritic cell for its branching, tree - like shape.

In doing so, specific cell types may activate immune responses to fine tune cell - fate decisions at the organismal level; for instance, DNA damage in germ cells induces an innate immune response in worms that promotes endurance of somatic tissues to allow delay of progeny production when germ cells are hit by DNA damage.

Today, Rudensky, a Howard Hughes Medical Institute Investigator and professor of immunology at Sloan - Kettering Institute in New York City, counts among the world's foremost immunologists for his discoveries on the molecular architecture of a type of immune cell implicated in autoimmune disorders, inflammatory disease, and cancer.

If it does, then you might use the approach of making more beta cells right at early onset of the type 1 disease to try and stop or reverse the immune attack, making the immune system think its made a mistake, inducing something called anergy by making more beta cells.

JDRF and ViaCyte share a continuing commitment to realizing the potential of beta cell replacement strategies to deliver insulin independence without immune suppression for people living with type 1 diabetes, and ultimately, at JDRF we hope this will move us forward in fulfilling our vision of a world without type 1 diabetes.»

The team analyzed the frequency of different types of immune cells in blood collected from 110 one year - old study participants, the presence of immune - stimulatory components in the subjects» house dust and asked whether any of the factors correlated with an increased of asthma at age seven.

11/6/2007 UCSD Researchers Discover Inflammation, Not Obesity, Cause of Insulin Resistance Findings may have important potential for new drug discoveries in fight against Type 2 diabetes Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that inflammation provoked by immune cells called macrop... More...

A team of chemical and biomedical engineers from the Cockrell School of Engineering at The University of Texas at Austin, in collaboration with researchers from the University of Pennsylvania, have discovered that HIV - infected patients experience a dysfunction in a certain type of immune cell: the follicular helper T (Tfh) cell.

In Sabrina's poster, she showed that patients with a low number of different types of T - cells (a type of immune cell which has different versions to fight different infections / diseases; called a T - cell repertoire or TCR) in their blood at start of treatment were more likey to respond to anti-PD1 therapy, and had a poor response to anti-CTLA4 therapy.

Up to a 30 % reduction in the incidence of type 1 diabetes mellitus is reported for infants who exclusively breastfed for at least 3 months, thus avoiding exposure to cow milk protein.13, 42 It has been postulated that the putative mechanism in the development of type 1 diabetes mellitus is the infant's exposure to cow milk β - lactoglobulin, which stimulates an immune - mediated process cross-reacting with pancreatic β cells.

At least 50 % of diabetic dogs have type 1 diabetes based on present evidence of immune destruction of β - cells.