Which cytokines are secreted by different
immune cell types following maturation and activation
Not exact matches
To better determine the role of specific chemoattractants in
type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's lab, used multiphoton intravital microscopy — an imaging technology pioneered for studies of
immune cell movements in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to
follow in real time the development of IC - induced arthritis in a mouse model of rheumatoid arthritis.
They were able to
follow the activity of the
immune cells using time - lapse 3 - D microscopy imaging of fish retinas and found that neutrophils, the
type of
immune cells that are typically the first responders to tissue injury, were largely unresponsive to photoreceptor death.
They found substantial differences
following influenza vaccination in the production of
immune - modulators that determine the
type of T -
cell response and in the proliferation and production of antibodies by B
cells.
Moreover, the increase in leukocyte infiltration is most striking when considering the total numbers of CD4 and CD8 T
cells, providing further evidence for a T
cell - mediated
immune response in the brain and / or meninges
following infection with attenuated
Type I parasites (Figure 3F).