A research team led by Michal Schwartz of Israel's Weizmann Institute of Science grew
these immune cells in a laboratory and implanted them into rats, and the transplants of the cells caused the axons to regenerate.
Working with human
immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular «off» switch for the inflammatory immune response that contributes to lung - constricting asthma attacks.
Not exact matches
By studying infected
cells grown
in a
laboratory, the team found that a large number of CMV's genes help it hide from the
immune system by allowing it to destroy many of the proteins produced by the body during virus infection and preventing them from activating
immune cells to destroy the virus.
The personalized vaccine is made from patients» own
immune cells, which are exposed
in the
laboratory to the contents of the patients» tumor
cells, and then injected into the patients to initiate a wider
immune response.
The team also compared the animals» responses to the therapy's effects
in laboratory cell samples and found that
in vitro studies did not predict how well the viral therapy and
immune response would fight tumor
cells in vivo.
In laboratory studies, daratumumab caused the targeted killing of CD38 - carrying tumor
cells by several distinct and potent mechanisms, including some that involve the
immune system.
Orit Matcovitch - Natan, a graduate student
in the
laboratories of both Amit and Schwartz, and other members of the two teams, studied the sole
immune cells present
in the brain — the microglia, which contribute to the brain's development and maintenance.
I was supporting myself with night - shift
laboratory work analysing
immune cells in blood samples flown
in by helicopter, often arriving after midnight... nothing related to my thesis.
Lo's
laboratory has for more than a dozen years studied
immune responses
in the gut and airways, focusing particularly on
cells which function as an early warning
in the
immune system.
Research
in the UCR School of Medicine
laboratory of David Lo found that certain
cells of the epithelium have a potentially important role
in immune surveillance — creating an electrostatic repulsion field to microbial invasion.
In collaboration with researchers at Winship Cancer Institute of Emory University, Ahmed's laboratory is looking for immune cells with similar characteristics in cancer patient
In collaboration with researchers at Winship Cancer Institute of Emory University, Ahmed's
laboratory is looking for
immune cells with similar characteristics
in cancer patient
in cancer patients.
X-ray studies at the Department of Energy's SLAC National Accelerator
Laboratory, combined with Stanford biological studies and computational analysis, revealed remarkable similarities
in the structure of binding sites, which allow a given T
cell to recognize many different invaders that provoke an
immune response.
Researchers can grow these lymphocytes
in the
laboratory with the help of substances, such as interleukin 2, that are produced by
cells of the
immune system.
In laboratory experiments, Dr. Weinberger and his team inserted a green fluorescent protein, or «vector,» into the DNA of Jurkat T lymphocytes — a type of white blood
cell that helps maintain a healthy human
immune system.
Recently, our
laboratory discovered that fungi secrete sugars that can act as a glue
in order to help fungi attach to human lung
cells and hide from the
immune system during lung infections.
Our
laboratory has assembled a comprehensive set of tools for doing this, including mice with conditional ablation of the Btla gene
in different subsets of
immune cells.
Our
laboratory is interested broadly
in the interface between the innate and adaptive
immune systems, and the unique subsets of T lymphocytes that bridge these systems by adopting properties that are very characteristic of innate
immune cells.
After working on innate
immune signaling at a Biotech startup company she studied mechanisms of signaling specificity as a postdoc
in Dr. Alexander Hoffmann's
laboratory at the University of California, San Diego before joining the Molecular
Cell editorial team
in 2013.
The findings have implications for the design of cancer vaccines and what are called adoptive T
cell therapies; when T
cells are collected from a patient and grown
in the
laboratory, increasing
in number before they are given back to the patient to help the
immune system fight disease.
«How can we determine what the
immune system is going to do, and then how can we control that response, not only with
cells in the
laboratory, but also
in an animal or a patient.»
Hedrick, whose
laboratory will focus on the role of cholesterol and LDL
in reprogramming specific subsets of
immune cells as part of the Program Project Research grant, has assembled a high - powered, multi-institutional team, including investigators from UC San Diego and the University of Virginia.
It uses
cells and molecules, either manufactured naturally by the body or created
in a
laboratory, to improve and restore the
immune system function.
«Having a very efficient and practical way of generating patient - specific stem
cells, which unlike human embryonic stem
cells, wouldn't be rejected by the patient's
immune system after transplantation brings us a step closer to the clinical application of stem
cell therapy,» says Belmonte, PhD., a professor
in the Gene Expression
Laboratory and director of the Center of Regenerative Medicine
in Barcelona, Spain.
Dr. Locksley's
laboratory focuses on tracking cytokine expression
in model systems, as a mechanism to investigate complex functional interactions between innate and adaptive
cells in the
immune system.
In the future, scientists may be able to modify human stem cell lines in the laboratory by using gene therapy or other techniques to overcome this immune rejectio
In the future, scientists may be able to modify human stem
cell lines
in the laboratory by using gene therapy or other techniques to overcome this immune rejectio
in the
laboratory by using gene therapy or other techniques to overcome this
immune rejection.
Laboratory model of
immune system overcomes ethical constraints on studies of hematopoietic stem
cells in humans.
My
laboratory aims to identify, characterize and validate lncRNA - driven pathways active
in allergy - driving helper T
cells and airway epithelial
cells that could hold promise as therapeutic targets
in altering the aberrant
immune responses underlying asthma.
According to the researchers, some existing data shows inflammatory markers can be increased and
immune cells activated when sleep is curtailed for a limited time
in a
laboratory setting.
The findings were made
in laboratory cell cultures and do not prove that similar results would occur as a result of dietary intake, the scientists said, but do add more interest to the potential of some foods to improve the
immune response.
Re-directed Autologous T
cell Therapy for drug resistant or refractory CD20 + B
cell lymphoma Overview:
In this approach, immune cells (known as T cells) are taken from the peripheral blood, genetically modified in the laboratory to express a receptor that recognizes B cells, and then expanded to produce large numbers of tumor specific T cells outside -LSB-..
In this approach,
immune cells (known as T
cells) are taken from the peripheral blood, genetically modified
in the laboratory to express a receptor that recognizes B cells, and then expanded to produce large numbers of tumor specific T cells outside -LSB-..
in the
laboratory to express a receptor that recognizes B
cells, and then expanded to produce large numbers of tumor specific T
cells outside -LSB-...]