Sentences with phrase «immune cells into»

Your immune cells into your thyroid and exacerbate that autoimmune attack.

It turns out the arrhythmia was caused by sarcoidosis, a rare intrusion of immune cells into the heart.

Now, patients with pancreatic cancer desperate for new treatment options will potentially benefit from a powerful new technology that uses genetic engineering to turn their own immune cells into «specially trained assassins» capable of finding, attacking, and eliminating pancreatic cancer tumors.

• Using this technique, the researchers were able to nearly eliminate the allergic reaction by converting allergen - sensitive immune cells into cells that mimic the response seen in healthy, non-allergic individuals.

The study focused on pancreatic ductal adenocarcinoma (PDA), a lethal form of cancer known to come with an influx of immune cells into tumors.

This was used in combination with another adenovirus vector carrying an immune stimulatory protein, cytokine, to recruit immune cells into the tumor.

Put broadly, CpG sets off a fire alarm within the body, springing immune cells into action.

Damaged mouse sciatic nerves produced hundreds of times the normal amount of two «chemoattractant» molecules, Cxcl1 and Cxcl2, which attach to the surfaces of neutrophils and draw the immune cells into injured tissue.

The biotech has been jockeying against main rivals Novartis and Juno to secure a first - to - market advantage with the groundbreaking new medical tech, which turns patients» immune cells into souped - up, re-engineered cancer killers that are then reintroduced into the body.

Biotech giant Gilead Sciences is beefing up its cancer drug portfolio with a $ 11.9 billion deal to buy Kite Pharma, a company focused on a groundbreaking new class of treatments that turns the body's own immune cells into targeted blood cancer killers.

Speaking of Novartis — the company's experimental CTL019, which is expected to be the first approved drug in a revolutionary new cancer treatment space that turns the body's own immune cells into cancer - killers, is already facing some apprehension from doctors and patient groups who are worried about its eventual pricing.

Not exact matches

Basically, CAR - T therapy involves taking a patient's own immune «killer» T - cells, inserting new genetic code into those cells which turn them into cancer - hunters that can home in on malignant B - cells (another kind of immune cell), and then pumping these specialized leukemia - busting cells back into the patient.

The treatment is a type of so - called CAR T - cell therapy — taking a patient's own immune cells, called T cells, genetically manipulating them to attack specific proteins on cancer, and infusing them back into the patient.

In clinical trials the treatment — which involves extracting individual patients» immune T - cells, modifying them to seek out tell - tale biological markers associated with blood cancers like aggressive lymphoma, and then pumping those modified killer cells back into the body — has shown major promise, in some cases eliminating all signs of the cancer in patients six months after treatment.

Those two companies, along with their larger competitor Novartis (nvs), are developing experimental chimeric antigen receptor T - cell (CAR - T) technology platforms, which are highly personalized treatments that involve extracting patients» immune cells, re-engineering them to target their specific cancers, and then pumping these sniper - cells back into the body.

The novel treatment space involves transforming a patient's own immune T - cells into cancer - busting weapons.

CRAC channels control the entry of calcium into immune and other cell types, and calcium is an important intracellular signaling molecule that modulates cytokine production and the immune response.

Bellicum is among the flurry of biotechs investing heavily into cell therapies such as experimental chimeric antigen receptor T - cell (CAR - T) treatments for cancer (this is the next - gen treatment that involves reprogramming immune cells to become cancer killers and has shown promise in blood cancers, which Bellicum specializes in).

This new kind of approach to fighting blood cancers is truly personalized; immune T - cells are extracted from patients, genetically tinkered to home in on an destroy cancerous cells, multiplied in a lab, and then jolted back into the patient's body within about two weeks.

Or consider a vaccine that, when injected directly into a tumor, would not only destroy the malignant cells but also stimulate the body's immune system to go after similar tumor cells.

The tattooing process works by injecting ink into the skin, which stimulates an immune response in which cells called «macrophages» move into the area and «eat up» the ink.

The drug has an unfortunate side effect of tricking the immune system into attacking healthy cells, but the relative damage was insignificant compared to what cancer would have done to them.

The old episode on the immune system took us into the blood vessels and showed us the drama of white blood cells marking strep bacteria for death, then engulfing and digesting them.

Autoimmunity is commonly caused by bacterial infections or overgrowth in the small intestine, in which partially digested food compounds are incorporated into bacterial cell walls and then the immune system, reacting to the bacteria, forms antibodies that also recognize food compounds, some of which might cross-react with human counterparts.

Clamping the cord, especially at an early stage, may also cause the extra blood trapped within the placenta to be forced back through the placenta into the mothers blood supply with the third stage contractions.32 33 This feto - maternal haemorrhage (FMH) increases the chance of future blood group incompatibility problems, which occur when the current baby's blood enters the mother's blood stream, causing an immune reaction which can be reactivated in a subsequent pregnancy, destroying the baby's blood cells and causing anaemia or even death.

This article is questionable as it has no links or actual references to the studies it talks about, like someone above has mentioned also there is no information on how the diagnosis were made, and lastly it does not take into account that celiac disease is NOT an allergy, it is an auto immune disease where the body attacks its own cells confusing them with gluten proteins, it is not about tolerance, I would not be trusting this information, do lots of research on your own from legitimate scientific sources before making a decision.

«These attacks have grown in magnitude and they include attacks on security services, we have incidents where military officers have been lynched by mobs, we have instances where these vigilante groups calling themselves variously; Invisible forces, Delta forces, etc. invade police stations, break into cells and release suspects because they claim the NPP members are immune to any form of arrest in other words, they are living above the law because they happen to be members of a party living in power», he said.

Researchers found that NAD +, a natural molecule found in living cells, plants and food protects against autoimmune diseases by altering the immune response and turning «destructive» cells into «protective» cells.

A decade ago a drug based on an internal protein of the flu virus, called NP (for nucleoprotein), set the immune system's killer T cells into action, but it only partially protected mice from the flu.

The team tested the technique on cells in culture that mimic the transformation of unspecialised white blood cells into full immune cells.

But during pregnancy, the fetus is protected from the mother's immune system by the placenta, which has specialized cells — called trophoblasts — that can burrow into the mother's body without exciting an attack by the immune system.

The goal of the new approach is to convert that immunosuppressive environment into an «immunostimulatory» one, Goldberg says — a condition in which the immune system is primed for an offensive against cancer cells.

Lagasse, based at Pitt's McGowan Institute for Regenerative Medicine, has discovered how to turn any one of the body's 500 lymph nodes — the small, oval - shaped organs where immune cells gather to fight invading pathogens — into an incubator that can grow an entirely new liver.

A decade ago, he replicated the entire human leukemia disease process by introducing oncogenes into normal human blood cells, transplanting them into xenografts (special immune - deficient mice that accept human grafts) and watching leukemia develop — a motherlode discovery that has guided leukemia research ever since.

The Australian team is now attempting to identify the strain of the man's virus to see how it compares to other HIV strains that require CCR5 to slip into immune cells.

The most common type of skin lymphoma is caused by the fact that specific immune cells — CD4 - T - lymphocyttes — turn into cancer cells.

In reaction to infection or inflammation, immune system cells known as effector T cells (Teffs) undergo rapid changes - arming themselves and diversifying into groups that target specific diseased cells.

A second type of immune system cell, called regulatory T cells (Tregs), are a model of constancy, remaining stable even as Teffs go into battle mode.

Only viruses that have mutated escape mechanisms from immune pressures are able to survive, but the mutations come at the cost of other aspects of viral fitness, perhaps inhibiting entry into cells or integration into cell DNA.

They use a near - infrared laser beam, which can penetrate deep — in this context, deep means a centimeter or two — into the tissue, where a nanoparticle turns the near - infrared light into blue light, and that directs the activity of genetically engineered immune cells.

They focused on the role of monocytes, immune cells that normally pass along the blood vessels and in response to a local infection move quickly into the affected organ and contribute to the localized immune defense there.

The inner surface is «greasy» and is believed to interact with cell membranes, while the outer surface, once secreted into the blood, can interact with the patient's immune system.

Last year, researchers at NIAID and elsewhere solved a decade - long mystery when they found that HIV uses a second set of proteins to gain entry into immune cells.

But if you put that same virus into a rhesus macaque, the monkey's immune system reacts similarly to that of humans; there is severe depletion of CD4 T cells and progression to AIDS, explains U.C.S.F. researcher Peter Hunt.

«It has been shown in mice that live immune cells in breast milk pass through the intestinal mucosa into the blood circulation of the pups and engraft in various tissues,» says Hassiotou.

«We believe that small subsets of metastatic tumor cells have the ability to adopt the mechanisms used by immune cells to exit the blood vessels into the lungs, the bone marrow, the brain, and other organs.

Researchers at Penn State have combined the two approaches by taking biodegradable polymer nanoparticles encapsulated with cancer - fighting drugs and incorporating them into immune cells to create a smart, targeted system to attack cancers of specific types.

Using cells from cadavers, doctors have been experimentally transplanting pancreatic islets into humans for decades, but as many as 60 percent of the transplanted islets die immediately because they are cut off from their blood supply and are killed by an immune response due to direct injection into the bloodstream, and those that survive the transplant usually die within several months.

Today, the paradigm has widened into a much bigger idea that expands our understanding of psychiatric disease: A whole host of infections and other unknown triggers lead to the production of antibodies and immune cells that can cross into the brain.

Researchers injected both the naked virus and SEVI - treated HIV into the tails of rats that had been given human immune system cells.