Sentences with phrase «immune cells produce»

The complex networks, interactions, and responses of immune cells produce diverse cellular ecosystems composed of multiple cell types, accompanied by genetic diversity in antigen receptors.

In healthy individuals, immune cells produce proteins called antibodies that attack foreign invaders to destroy them and clear them out of the system.

THE DEMENTIA associated with Alzheimer's disease may be caused by toxins that the body's own immune cells produce.

When activated by inflammatory markers in the gut, it sends a signal to the brain, where immune cells produce proteins such as IL - 6, leading to increased metabolism (and hence decreased levels) of the «happiness hormone» serotonin in the brain.

In both cases, the immune cells produced fewer inflammatory molecules, particularly one called interleukin 17, or IL - 17, which is strongly associated with MS and very harmful to nerve cells and their insulating covers.

The awards span the broad mission of the NIH and include groundbreaking research, such as engineering immune cells producing drugs at the site of diseased tissue; developing a sensor to rapidly detect antibiotic resistance of a bacterial infection; understanding how certain parasites evade host detection by continually changing their surface proteins; and developing implants that run off the electricity generated from the motion of a beating the heart.

Not exact matches

This type of diabetes strikes in the early teenage years and begins with the immune system destroying the cells in the pancreas that produce insulin, according to Patrick Holford, founder of the Institute for Optimum Nutrition in London.

Pregnant mothers who are Rh - and are carrying babies who are Rh + pose a threat to the baby because their immune system produces antibodies against their baby's red blood cells.

The baby's immune system starts functioning and produces blood cells: leukocytes and platelets.

Usually, the body's own immune system — which normally fights harmful bacteria and viruses — mistakenly destroys the insulin - producing (islet, or islets of Langerhans) cells in the pancreas.

Not just for vitamins (like A, B and C) that promote immune health and cell growth, but also to encourage your baby to eat plenty of produce later in life.

And while every body is filled with atypical cells, a healthy immune system stops them from producing at a rate to form cancers.

High levels of cortisol in the blood and separation from mother may negatively impact immune function as the body may stop producing leukocytes (infection fighting cells).

We found that when it comes to cutaneous immunity — specific to skin — the immune system was being obstructed by skin cells that were too prone to producing inflammation responses.

An engineered bone that has its own marrow can encourage donor stem cells to produce blood, a feat that could help people with anaemia and rare immune diseases

There were clear differences in the composition of immune cells in the wounds and the immune cells present produced higher levels of TGFß at earlier time points.

Two groups had their immune systems altered to produce fewer macrophages, the white blood cells that attack pathogens.

Damaged mouse sciatic nerves produced hundreds of times the normal amount of two «chemoattractant» molecules, Cxcl1 and Cxcl2, which attach to the surfaces of neutrophils and draw the immune cells into injured tissue.

Weissman's research in mice had revealed that cancer cells produce large quantities of CD47, a protein that signals immune cells to spare the cancer cells.

Infectious organisms trip specialized immune cells in the body and cause them to pump out proteins called cytokines, which produce inflammation and other hallmarks of infection, such as chills and fever.

Although such harvested cells could be cultured as say, liver cells for treating hepatitis or dopamine - producing cells for Parkinson's, the resulting transplants would likely be rejected by patients» immune systems.

Researchers are developing many different versions of CAR - T cell therapies, but the basic premise is the same: Doctors remove a patient's T cells (immune system cells that attack invaders) from a blood sample and genetically modify them to produce artificial proteins on their surfaces.

The process prepares the patient's body to accept the donated stem cells, reducing the risk of rejection and providing a hospitable environment for the new cells to engraft, thrive and produce new blood and immune cells.

The four children also had more of the types of species that are known to trigger gut inflammation, a possible prelude to type - 1 diabetes, in which the body's immune system mistakenly produces antibodies that attack and destroy the beta cells of the pancreas that normally make insulin.

The team produced 11 stem cell lines from 11 men, women, and children with conditions such as diabetes, spinal cord injury, and inherited immune deficiency.

The enzyme is produced by white blood cells called neutrophils, which play an important role in inflammatory and immune responses and may be a key contributor to the development of muscular dystrophy.

The disease commonly starts in childhood and causes the body's own immune system to attack and destroy the insulin - producing cells in the pancreas, leaving the patient dependent on life - long insulin injections.

By studying infected cells grown in a laboratory, the team found that a large number of CMV's genes help it hide from the immune system by allowing it to destroy many of the proteins produced by the body during virus infection and preventing them from activating immune cells to destroy the virus.

Specific immune cells have the ability to produce a healing factor that can promote wound repair in the intestine, a finding that could lead to new, potential therapeutic treatments for inflammatory bowel disease (IBD), according to a new research study.

The viruses also exploit an enzyme that cells use to destroy RNA to instead produce short stretches of RNA that, among other things, may help the virus avoid the immune system of its host.

In this study, the researchers found that a specific population of immune cells called macrophages have the ability to secrete or produce a protective or healing factor known as Interleukin - 10 (IL - 10), which can interact with receptors on intestinal epithelial cells to promote wound healing.

But roundworms seem to shift the balance of the immune system towards producing more type 2 T cells.

The dendritic cells «present» the virus to other immune cells that produce antibodies.

On encountering the TB bacillus, receptors on immune - system scavenger cells known as macrophages stimulate the conversion of circulating vitamin D to its active form, which produces a peptide that destroys the bacillus.

Interferons are molecules produced by cells in response to viral or bacterial infection, and which act on neighboring cells to prevent the spread of the infection, shut down protein synthesis, and activate the immune system.

Hookworm infections seem to provoke a mix of two different immune cells: type 1 T cells, which instruct other cells to directly attack pathogens, and type 2 T cells, which tell cells to produce antibodies.

This made it possible for their immune systems to produce sufficient amounts of CD8 T cells that were primed to attack and kill HIV - infected cells.

The new study revives suspicions that adenoviruses cause an immune «own goal», priming people's immune systems to produce CD4 cells — the very cells that HIV prefers to infect — and, worse still, to direct those cells to the parts of the body that are most vulnerable to the virus during sex.

This is because memory B cells, which remember antigens in the primary immune response, are induced and respond faster in the secondary exposure to bacteria or viruses and differentiate into antibody - producing cells.

There it passes on the fragments to other immune cells, which produce a distinctive fork - shaped antibody, known as immunoglobulin E, or IgE.

Both natural B cells (brown spots at left) and synthetic immune tissue (top right) produce antibodies.

A few years ago, MS researchers were focused on a new type of immune cell called the Th - 17 cell, which appeared to be a key player in driving the neuronal damage in MS. Because Th - 17 cells produce the cytokine IL - 17, researchers likewise thought this chemical was essential to the disease.

The human immune system wants to produce antibodies that bind to the glycoprotein to stop infection, but the glycans block immune cells from seeing their targets and developing useful antibodies.

They first showed that mice with severed sensory nerves produce excessive BH4, churned out both by the injured nerve cells themselves and by macrophages — immune cells that infiltrate damaged nerves and inflamed tissue.

University of Alabama at Birmingham researchers have now shown that activated T - cells — part of the immune system's inflammatory response — are both necessary and sufficient to produce such heart failure.

The bacteria produce substances that irritate the gut lining and make it more porous, admitting immune cells that trigger inflammation.

By combining multiple images, the researchers produced movies correlating the production of hydrogen peroxide to the activities of the immune system cells.

These are specialized immune cells that produce antibodies to fight milk proteins as part of the immune system.

These include pro-inflammatory T helper cells, or Th1, that produce interferon - γ and interleukin - 2, or IL - 2; anti-inflammatory Th2 cells that produce IL - 4, IL - 5 and IL - 13; pro-inflammatory Th17 cells that secrete IL - 17; and immunomodulatory regulatory T - cells, or Tregs, that globally suppress activation of immune responses.

In earlier studies involving animal models and human cancer cell lines, researchers found that breast cancer spreads when three specific cells are in direct contact: an endothelial cell (a type of cell that lines the blood vessels), a perivascular macrophage (a type of immune cell found near blood vessels), and a tumor cell that produces high levels of Mena, a protein that enhances a cancer cell's ability to spread.