Sentences with phrase «immune cells so»

One of the theories that's getting more and more traction is that those infections help regulate and mature our immune cells so they are not attacking self, and that perhaps these parasites have more of a symbiotic relationship than we appreciate.

MK - 3475 provides a shield for the immune cells so that they can remain active when they reach the tumor.»

«Protecting «self - reactive» immune cells so they can fight melanoma.»

The team genetically engineered immune cells so that a calcium gate - controlling protein became light sensitive.

Not exact matches

So research teams began souping up various types of immune cells and even targeting them to specific protein markers on tumors.

The treatment is a type of so - called CAR T - cell therapy — taking a patient's own immune cells, called T cells, genetically manipulating them to attack specific proteins on cancer, and infusing them back into the patient.

Tesaro has a coveted position as a leader in the so - called immuno - oncology sector, which harnesses the body's own immune system to combat cancer cells.

Colostrum is so full of antibodies, white blood cells, and other immune properties that it's like your child's first immunization.

So, the baby's immune cells are not likely to be exposed to the allergen at all.

It is packed with live immune cells that actively target and kill bacteria, so it takes longer to spoil than pasteurized cow's milk or formula.

Psoriasis (Ps) and psoriatic (so - rye - AT - ick) arthritis (PsA) are conditions of the immune system that affect the normal production of healthy skin cells on the body.

«Chronic inflammation of the intestine is thought to be caused by abnormal interactions between gut microbes, intestinal epithelial cells and the immune system, but so far it has been impossible to determine how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.

Humans have this type of blood cell, so it might be possible to create immune - tolerant organs for transplant.

Further study revealed that these so - called immune proteins are actually present on the surface of certain nerve cells, but that they functioned differently in the brain than they did in the rest of the body; rather than scouting for germs, they influenced signals sent between neurons.

They discovered a population of NKT cells that have a gene that controls so - called regulatory T - cells, whose role is to suppress the immune response.

It indicates to the immune system that a cell is «self,» and so not to be attacked.

Tissue - engineered livers grown from stem cells, say, could have their genetic code altered so that they would be immune to liver - destroying viruses such as hepatitis C.

Patients with metastatic non-small cell lung cancer will always progress after chemotherapy, so most patients go on to be treated with immunotherapy, a type of therapy that uses the body's immune system to fight cancer.

The so - called STEP trial, sponsored by pharmaceutical giant Merck & Co. and the federally funded HIV Vaccine Trials Network (HVTN), was the first to test the idea of stimulating the immune system's killer T cells to hunt for the virus more aggressively, in this case using a weakened form of the cold virus to carry three genes from HIV.

Additionally, immune cells are located deep in the body and are constantly moving around, so getting the light to them can be difficult.

However, those antibodies also bind to leiomodin - 1, so the immune system - incorrectly - will attack brain cells that contain that protein, which can result in symptoms of Nodding syndrome.

More light leads to a greater flow of calcium, so the researchers are able to finely tune the calcium - dependent actions of immune cells to fight against invading pathogens or tumor cells.

Essentially, it mimics the disease so that the immune cells recognize it, and the body stocks up on the immune cells with a barcode specific for that disease.

The cells were derived from eggs that had been injected with DNA from the patients, so they could eventually be transplanted back to replace or correct the patient's diseased cells without fear of immune rejection.

The immune system can reveal so much because the cells that make it up are so diverse.

But if we changed the code of the host cells, it would thwart the virus's ability to replicate, and so make the host immune.

One plausible explanation was that over the course of successive population crashes, the devils had become so inbred that their cells look identical — at least to the animals» immune systems.

So Swanton is focusing on immunotherapies — strategies that help the immune system to recognize and destroy cancer cells.

In particular, it has evolved to show itself three to nine months after infection, allowing its own destruction by displaying antigens on its cell surfaces so the dog's immune system can destroy it.

So it seemed shocking that devil immune systems would fail to recognize and stomp out something as obviously foreign as another devil's cancer cells.

BREAKING DOWN MULTIPLE SCLEROSIS Taking narrow aim at the immune system isn't enough, so researchers are looking for new treatment targets within nerve cells and even in the gut.

So far, scientists have been able to listen to bits and pieces of the conversation between bacteria and individual immune cells or a handful of genes.

Others include transplanting so - called Schwann cells from peripheral nerves, using growth factors to stimulate nerve growth, and boosting the immune system in the damaged area (New Scientist magazine, 14 August 1999, p 36).

So far she has treated mice with the engineered cells, which give rise to HIV - resistant immune cells.

This is important as one of the reasons tumour cells are so pernicious is that they are able to hide from the body's immune system, by hijacking macrophages.

Immune therapy for ovarian, breast and colorectal cancer — treatments that encourage the immune system to attack cancer cells as the foreign invaders they are — has so far had limited success, primarily because the immune system often can't destroy the cancer cells.

«What's remarkable is that B cells are the ones making antibodies and autoantibodies, so they're really crucial in both protective immune responses and autoimmunity,» said Montserrat C. Anguera, assistant professor in the Department of Biomedical Sciences in Penn's School of Veterinary Medicine and the senior author on the study.

The mouse model could also contribute to the further development of immunotherapies — a method in which the body's immune system is stimulated, so that it intensifies its fight against tumor cells.

However, if it, so to speak, pockets the retinoic acid, then the immune cells react moderately, without an allergic immune reaction.

Smoke inhibits activity of so called mast cells, which drive the immune system's response to allergens.

Injected mRNAs normally would be cleared from the body within minutes by a patient's immune system, but these mRNAs are modified so that they are ignored by the immune system and can easily enter cells.

Specialized immune cells are formed which produce antibodies against the milk proteins and so trigger a potentially much more dangerous allergic reaction.

Thus, Ebola appears to work not by preventing an immune response altogether but by moving so swiftly that the T cells do not have time to multiply enough to mount an effective counterattack.

Researchers at Dartmouth - Hitchcock Norris Cotton Cancer Center are exploring ways to wake up the immune system so it recognizes and attacks invading cancer cells.

BCL - 2 is a so - called «pro-survival» protein that makes normal immune cells survive for extended periods.

If so, perhaps you could make more resident memory cells for that particular organ to bolster the immune response.»

- GalCer ligands serve as tiny dock masters in our immune system, helping antigen - presenting cells attract and bind with iNKT cells so they can be activated to kill cancerous cells or fight off pathogens and other foreign invaders.

So - called Natural killer (NK) cells are innate immune cells and responsible for the elimination of cancerous cells.

In a new study published in Science Advances, a group of University of Wisconsin - Madison researchers show that individual cells in the human body have an armament designed to prevent HCMV from achieving and maintaining this latency, to shine a spotlight on the virus so the immune system knows to fight.

Transplanted embryonic stem cells are ethically cleaner, but they have a genetic makeup different from the patient's own, so they could be violently rejected by the immune system.