The known FPRs include two immune system receptors that detect chemicals given off by pathogens in the blood, helping
immune cells track down and attack foreign bodies.
Not exact matches
If they can be used in living tissue, they might eventually
track cells in developing embryos, the
immune system, or cancerous tumors.
They might be put to use right away to
track cultures of
immune cells as they migrate in response to chemical stimuli.
The cancer
cells» defense strategy can be overcome by
immune checkpoint inhibitor agents, including anti-PD-1 / PD - L1 antibodies, several kinds of which have received fast -
track approval from the U.S. Food and Drug Administration (FDA).
After initiating photoreceptor loss in the fish retinas, the researchers monitored the
immune system's response by
tracking the activity of three types of fluorescently labeled
immune cells in and around the eye: neutrophils, microglia and peripheral macrophages.
Zebrafish larvae and fluorescently marked
immune cells allow researchers to
track immune system activity in a model of retinal degeneration.
Monitoring
immune cell activity — including phenotyping
immune cell subsets,
tracking cell proliferation, and measuring cytokine production — can provide insights into the overall status of
immune function in patients, particularly those undergoing immunosuppression after transplants, enduring cancer treatment, or suffering from autoimmune disease or other pathologies that affect the
immune system.
The research team used blood samples taken daily throughout the patient's hospitalization and recovery to measure the rise and decline of virus replication inside white blood
cells and serum and to
track the timing, intensity and duration of expression of numerous
immune system genes.
Researchers at the
Cells - in - Motion Cluster of Excellence at the University of Münster (Germany) have now developed a method enabling them to better evaluate and study the activity of inflammatory cells in mice: they have succeeded in genetically modifying precursors of immune cells, then increasing their numbers in a test tube and finally tracking them spatially and temporally in living organ
Cells - in - Motion Cluster of Excellence at the University of Münster (Germany) have now developed a method enabling them to better evaluate and study the activity of inflammatory
cells in mice: they have succeeded in genetically modifying precursors of immune cells, then increasing their numbers in a test tube and finally tracking them spatially and temporally in living organ
cells in mice: they have succeeded in genetically modifying precursors of
immune cells, then increasing their numbers in a test tube and finally tracking them spatially and temporally in living organ
cells, then increasing their numbers in a test tube and finally
tracking them spatially and temporally in living organisms.
The rearrangements allowed Ellebedy and his colleagues to
track the activated B
cells, like DNA bar codes, as an
immune response progresses.
To better understand what happens during
immune reactions in the body, researchers at Tübingen University have developed a new way of labeling T -
cells, allowing them to
track the T -
cell movement in mice using non-invasive positron emission technology (PET).
«We would be able to mark the treated
immune cells as we did the T -
cells and to
track whether they migrate to the tumors as planned,» says Kneilling.
Another possibility is attaching the contrast agent to
immune cells engineered to attack a patient's tumor, allowing the
cells to be
tracked inside the body.
They
tracked the
cells to the spleen, which serves as a staging area for
immune cells.
Instead, the new test could be used to
track the effectiveness of medicines and other measures intended to dampen the
immune assault that kills beta
cells.
«Individual
cells in the body are able to keep
track of time using their biological clocks, including
immune cells that respond to infectious diseases.
Some of their goals include the unravelling of disease mechanisms by using nanomaterials to
track cellular components and probe the chemical niche of the
cells, the transformation of adult human
cells into induced pluripotent stem
cells and the delivery of drugs directly to
immune and cancer
cells.
Dr. Locksley's laboratory focuses on
tracking cytokine expression in model systems, as a mechanism to investigate complex functional interactions between innate and adaptive
cells in the
immune system.