Sentences with phrase «immune checkpoint treatment»

Not exact matches

One recent tally found more than 1100 studies combining a popular new class called checkpoint inhibitor drugs, which unleash suppressed immune cells, with other treatments.

Checkpoint inhibitors, which aim to unleash the power of the immune system on tumors, are some of the most impressive new cancer treatments.

Commenting on the two studies, Baas says that finding a good treatment for mesothelioma has been a challenge for many years and has so far led to many disappointments, so there is a need for investigation into new pathways such as the use of immune checkpoint inhibitors that target the PD - 1 / PD - L1 pathway.

Researchers led by Van Allen and Choueiri sought an explanation for why some patients with a form of metastatic kidney cancer called clear cell renal cell cancer (ccRCC) gain clinical benefit — sometimes durable — from treatment with immune checkpoint inhibitors that block the PD - 1 checkpoint, while other patients don't.

«Cancer treatment for transplant patients discovered: Letter notes combination of steroids and immunosuppressants, combined with immune checkpoint inhibitors helps prevent organ rejection in kidney transplant patients undergoing cancer treatment.»

The novel drug combination allows the rapidly emerging cancer therapies called immune checkpoint inhibitors to be incorporated into a transplant patient's cancer treatment regimen.

ALEXANDRIA, VA, FORT WASHINGTON, PA. — Immunotherapy with immune checkpoint inhibitors is the first of a new generation of immunotherapy treatments, revolutionizing treatment for many different types of cancer.

At that point, they began treatment with the drug pembrolizumab, which inhibits the PD - 1 immune checkpoint.

For their collective contributions to the pre-clinical foundation and development of immune checkpoint blockade, a novel form of cancer therapy that has transformed the landscape of cancer treatment.

Through strategic partnerships with industry and nonprofit organizations, we gain access to a portfolio of priority drugs for testing within our expert focus groups, including checkpoint inhibitors, therapeutic vaccines, innate immune stimulants, targeted therapies, and many other promising treatments and technologies with high therapeutic potential.

T - cells (red, yellow, and blue) attack a tumour in a mouse model of breast cancer following treatment with radiation and a PD - L1 immune checkpoint inhibitor, as seen by transparent tumour tomography.

These treatments can be broken into four categories: monoclonal antibodies, checkpoint inhibitors and immune modulators, cancer vaccines, and adoptive cell therapy.

«We showed that there are markers on these stomach tumour cells that indicate they would be responsive to a type of immunotherapy called immune checkpoint inhibitors, in particular anti-PDL1 immunotherapy, which is already used with great success in the treatment of melanoma and certain other cancers.

A potentially promising avenue of treatment in leukemia is the use of immune checkpoint inhibitors.

Head and neck cancer has one currently approved immunotherapy, the checkpoint inhibitor nivolumab (Opdivo ®) and is one of the major cancer types for which new immune - based cancer treatments are in development.

These treatments can be broken into 5 main categories: checkpoint inhibitors / immune modulators, adoptive cell transfer, monoclonal antibodies, therapeutic vaccines, and cytokines.

Led by Leena Gandhi, MD, PhD, associate professor of medicine and director of thoracic medical oncology, researchers from the KEYNOTE - 021 study demonstrated for the first time that combining an immune checkpoint inhibitor — in this case, pembrolizumab — with a platinum - doublet chemotherapy regimen might be more effective than chemotherapy alone as first - line treatment for advanced, non-squamous NSCLC.

In honor of James Allison, Lieping Chen, Gordon Freeman, Tasuku Honjo and Arlene Sharpe for contributions to the pre-clinical foundation and development of immune checkpoint blockade, a novel form of cancer therapy that has transformed the landscape of cancer treatment.

Mismatch repair (MMR)- deficient cancers have been discovered to be highly responsive to immune therapies such as PD - 1 checkpoint blockade, making their definition in patients, where they may be relatively rare, paramount for treatment decisions.