Sentences with phrase «immune components in»

In 2010, we formally demonstrated ADE by developing a mouse mode of ADE - mediated disease, and we began to dissect the contribution of humoral vs. cellular immune components in dengue vaccine - mediated protection using model vaccine candidates as tools to probe the mechanisms by which the vaccine - induced immune responses in mice contribute to protection vs. ADE.

Therefore, the composition of immune components in the breast milk of lactating mothers is likely an important factor in whether breast - fed infants are protected against disease.

Hansen, Lars IMMUNOBIOLOGY OF HUMAN MILK: How Breastfeeding Protects Infants Pharmasoft Publishing, 2004 In this unique resource, the biology of the immune components in human milk and how they protect the breastfed infant is explained.

Not exact matches

While much is still being learned about why, it's believed that the immune system, which has a memory component, can be «re-educated» to recognize cancer in an enduring way, in the same way it recalls its response to pathogens long ago, says Suzanne Topalian, director of the melanoma program at Johns Hopkins.

In addition, Red Star Nutritional Yeast contains other beneficial components, such as beta - 1,3 glucan and mannan, complex carbohydrates known to improve the immune response and help maintain cholesterol levels that are already within a healthy range; trehalose, a disaccharide that helps maintain the health of brain cells; and glutathione, an antioxidant that plays an important role in cellular defense mechanismIn addition, Red Star Nutritional Yeast contains other beneficial components, such as beta - 1,3 glucan and mannan, complex carbohydrates known to improve the immune response and help maintain cholesterol levels that are already within a healthy range; trehalose, a disaccharide that helps maintain the health of brain cells; and glutathione, an antioxidant that plays an important role in cellular defense mechanismin cellular defense mechanisms.

Many components of green drink cocktails are said to be effective in lowering bad cholesterol level, improving digestion and strengthen the immune system.

The role of bioactive components, such as cytokines, hormones, growth factors (GFs) and fatty acids (FAs) is poorly known, but they might be implicated in immune response development.

Mothers» milk is exceptionally beneficial for these preterm infants, as it contains numerous bioactive immune components, essential proteins and fats which are not present in commercially made formula.

A component in the formation of collagen — a protein used to build bone, cartilage, muscle, and connective tissue — vitamin C helps maintain healthy blood vessels, heal wounds, absorb iron, and support immune function.

Not being breastfed can disrupt optimal growth and development, especially in the first two years, when the key components of the immune system are forming to protect the child for life from chronic illnesses such as diabetes, cancer, and autoimmune diseases.

One is that the special components of breast milk give protection against exposure to viruses, which in turn leads to a stronger immune system.

The molecule in question, known as beta - 2 microglobulin, or B2M, is a component of a larger molecule called MHC I (major histocompatibility complex class I), which plays a major role in the adaptive immune system.

«The results are novel, as this sensitive and comprehensive testing has revealed how prenatal and early postnatal immune activation may regulate core behavioral signs associated with ASD and certain other developmental disorders through changes in signal flow between different structural components of behavior - driving neural circuits,» said Bolshakov.

Lymphoma in animals is a malignant cancer originating from lymphocytes, which are an important component of the immune system.

Pre-clinical studies have shown that ALT - 803 activates the immune system to mobilize lymphocytes against tumor cells and could potentially serve as an important component in combination treatments.

Researchers at Nagoya University have been studying the therapeutic effect of T cells, vital disease - fighting components in our body's immune system, for fighting cancer.

An unknown component of breast milk appears to kill HIV particles and virus - infected cells, as well as blocking HIV transmission in mice with a human immune system.

«Along with the eggs, the parasitoid injects a symbiotic virus that knocks out the immune system of the caterpillar and kill the component in the caterpillar saliva that signals the plant that it is being attacked.»

A tangle of virus and antibodies in their lungs activated an immune system component called complement, which failed to clear the mess and instead attacked lung tissue.

In a phase 2 trial that included nearly 1,000 adults, the AS03 and MF59 adjuvants (a component that improves immune response of inactivated influenza vaccines) increased the immune responses to two doses of an inactivated H7N9 influenza vaccine, with AS03 - adjuvanted formulations inducing the highest amount of antibody response, according to a study in the July 21 issue of JAMIn a phase 2 trial that included nearly 1,000 adults, the AS03 and MF59 adjuvants (a component that improves immune response of inactivated influenza vaccines) increased the immune responses to two doses of an inactivated H7N9 influenza vaccine, with AS03 - adjuvanted formulations inducing the highest amount of antibody response, according to a study in the July 21 issue of JAMin the July 21 issue of JAMA.

Analyses of the saliva revealed that one of its protein components, known as SP15, appeared to elicit a natural immune response in mice.

«Hard to imagine that these vessels would not be involved in a [neurological] disease with an immune component.»

«It's early to speculate,» Kipnis says, «but I think that alteration in these vessels may affect disease progression in those neurological disorders with a prominent immune component, such as multiple sclerosis, autism and Alzheimer's disease.»

Specifically, they determined that the immune systems in genetically altered mice lacking the critically important calcium channel component STIM1 failed to control TB, leading to severe lung inflammation and premature death.

To simulate an infection, mice were injected with lipopolysaccharides (a component of the bacterial cell wall), which results in an immune response and generalized disease symptoms.

Shortening these RNAs enables Integrated DNA Technologies to manufacture the components as high - quality, synthetic RNA oligonucleotides that elicit less toxicity and innate immune response activation in cells.

This is an illustration showing interactions between components of the AH10 - 7 compound (yellow), an immune system antigen - presenting cell (gray), and an invariant natural killer T cell (green and blue) that spark activation of iNKT cells in «humanized» mice.

But if the immune system is indeed attacking the corneal protein identified by the Cantor group, the discovery could «in principle allow us to disrupt or arrest this component» of the attack, says M. Reza Dana, an ophthalmologist and ocular immunologist at Harvard Medical School, perhaps by inactivating the specific set of immune cells responsible for it.

Kipnis and his team first suspected a link between the immune system and social behavior when they found that mice lacking T cells, key components of the immune system, show little interest in their peers.

But Claudia Guida, a PhD student in the group jointly led by Matthias Hentze at EMBL and Martina Muckenthaler at Heidelberg University Clinic, found that ferroportin can be dialled down independently of hepcidin, by triggering responses from TLR2 and TLR6, two molecules our immune system uses to detect bacterial components.

Researchers at Albert Einstein College of Medicine in New York City wondered if having a gD - 2 component in a vaccine might «mask» other viral particles and allow them to escape immune detection.

Back in the Netherlands, scientists gave both the twelve trained subjetcs and twelve healthy non-trained volunteers an injection containing endotoxin, a component from the cell - wall of bacteria that elicits a response from the immune system.

Looking for immune abnormalities throughout the lifespan of the mice, the group found that most immune system components stayed the same in number, but a type of brain - resident immune cells called microglia that are known first responders to infection begin to divide and change early in the disease.

One drug, Protolin, contains bacterial components that rev up immune - system cells in the brain, called microglia, to chew through the beta - amyloid.

«One possibility is that components in the blood of younger donors or female donors may affect the immune system of the transfusion recipient.»

«We have revealed novel components and connections in the regulatory network underlying how these T cells mount an immune response,» said study co-leader Kai Tan, PhD, of the Center for Childhood Cancer Research and the Departments of Pediatrics and Biomedical and Health Informatics at CHOP.

In a real allergy, immune components such as IgE antibodies in the blood are stimulated by an allergeIn a real allergy, immune components such as IgE antibodies in the blood are stimulated by an allergein the blood are stimulated by an allergen.

To cross the species barrier and establish themselves in the human population, influenza strains must acquire mutations that allow them to evade components of the human immune system, including, perhaps, the innate immune protein MxA.

• The key component of this research is dendritic cells, which serve as the gate - keepers of the immune system and are present in tissues in contact with the external environment, such as the skin and the inner lining of the nose, lungs, stomach and intestines.

The discovery suggests that blocking this immune system component may help reduce inflammation in human autoimmune and hyper - inflammatory diseases such as rheumatoid arthritis and Type 2 diabetes.

Immunosenescence describes the complex set of changes that occur in all components of the immune system, as well as the local environment, that result in loss of immune function as we age.

Turmeric boasts an astonishing array of antioxidant, anticancer, antiviral and antibiotic properties, and as an immune system booster, it's stronger than vitamins C and E. Curcumin is better absorbed with piperine, an active component in black pepper.

Systems biology research will aim to identify and validate mathematical models that can accurately predict interactions between immune system components in relation to vaccination, as well as develop state - of - the - art methods for the structural and functional analysis of vaccine candidates.

The discovery could prove to be a major asset in the fight against several pathologies via the targeting of a single immune cell component.»

Charles Janeway introduces the hypothesis that «components of the innate [immune] system, especially antigen - presenting cells such as DCs, required the microbial stimuli contained in [adjuvants] to become activated and acquire the capacity to induce productive responses from antigen - specific lymphocytes.

In the late 1960s, Rowley and his graduate student Donald Mosier were the first to describe the function of a previously unrecognized cell type, a component of the adaptive immune system they labeled the «A cell,» for its «adherent, accessory or antigen - presenting capacity.»

A research team from the German Leibniz Institute for Zoo and Wildlife Research (IZW) recently discovered that cheetahs have developed a very efficient innate «first line of defence» immunity to compensate potential deficiencies in other components of their immune system.

To better understand how these normally helpful components of the immune system are put to nefarious tasks in cancer cells, Verma and his colleagues developed a new method of inducing non-small-cell lung cancer in mice.

Autoantigens trigger the immune system to produce antibodies that attack the body's own components, resulting in autoimmune disease.

While homology - based approaches are likely to be reliable for well - conserved pathways such as the core signaling components of the innate immune network, it is difficult to confidently assign function to the numerous proteases, protease inhibitors, and similarly diverse gene families in the absence of direct functional information.