Not exact matches
Only viruses that have mutated
escape mechanisms from
immune pressures are able to survive, but the mutations come at the cost of other aspects of viral fitness, perhaps inhibiting entry into cells or integration into cell DNA.
In addition to formulating diagnostic strategies for cancer immunotherapy agents, her team is focused on developing a deep understanding of tumor
immune biology as well as
mechanisms associated with
immune response and
immune escape in cancer patients, with the intent of generating rational strategies for the creation of combination therapies.
A research group at Hiroshima University demonstrated the
mechanism by which the Sendai virus (SeV)
escapes the host
immune system.
Cancer cells can leverage such
mechanisms to
escape the
immune system response.
Poggi A, Musso A, Dapino I, Zocchi MR.
Mechanisms of tumor
escape from
immune system: Role of mesenchymal stromal cells.
Among his most important accomplishments was the description of a key
mechanism by which tumor cells can
escape the host
immune system.
Background: Expression of programmed death ligand (PD - L1 / B7 - H1 / CD274) represents a
mechanism of
immune escape for renal cell carcinoma (RCC) cells.
More recently, we have learned that it is critical to understand the biology of cancer plasticity to identify the
mechanisms that allow tumours to resist or
escape immune control.
April 17, 2018 - In our efforts to better understand how HIV
escapes the effects of the
immune system, scientists have discovered a new
mechanism that could hold the answer.
Here, we review the current state of the art of somatic cancer evolution and
mechanisms of
immune control and
escape.
One of these
escape mechanisms involves a type of
immune cell called myeloid - derived suppressor cells (MDSCs).