Sentences with phrase «immune gene signatures»

We also have longstanding collaborations with GlaxoSmithKline to study inhibitors of the MAPK pathway in immune cells and melanoma, tumour antigens and predictive immune gene signatures.

Not exact matches

The gene signature identified by Hancock and his colleagues relates to a special type of immune suppression called cellular reprogramming and suggests that treating inflammation in sepsis is a bad idea.
When the team looked at what gene signatures the RORγt - dependent ILCs expressed, they found high expression of major histocompatibility complex class II (MHCII) protein, which some cells use to display foreign proteins to the immune system and directly interact with T cells.
Nevertheless, variations in evolutionary signatures of selection amongst immune genes from bumblebees and honeybees may point to different pressures exerted by the distinct pathogens that threaten these bees.
LUMC offers an extended multiplex transcriptome profiling assay (dcRT - MLPA) for monitoring innate, adaptive and inflammatory immune - response signalling gene signatures, which can be used to evaluate and improve immunisation strategies.
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