We also have longstanding collaborations with GlaxoSmithKline to study inhibitors of the MAPK pathway in immune cells and melanoma, tumour antigens and predictive
immune gene signatures.
Not exact matches
The
gene signature identified by Hancock and his colleagues relates to a special type of
immune suppression called cellular reprogramming and suggests that treating inflammation in sepsis is a bad idea.
When the team looked at what
gene signatures the RORγt - dependent ILCs expressed, they found high expression of major histocompatibility complex class II (MHCII) protein, which some cells use to display foreign proteins to the
immune system and directly interact with T cells.
Nevertheless, variations in evolutionary
signatures of selection amongst
immune genes from bumblebees and honeybees may point to different pressures exerted by the distinct pathogens that threaten these bees.
LUMC offers an extended multiplex transcriptome profiling assay (dcRT - MLPA) for monitoring innate, adaptive and inflammatory
immune - response signalling
gene signatures, which can be used to evaluate and improve immunisation strategies.