Sentences with phrase «immune mechanisms against»
Unfortunately, despite all the knowledge the scientific community has regarding immune mechanisms against cancer, there is still a lot more to dig in.
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The logic is indirect, autophagy is a key innate immune mechanism against intracellular pathogens and protein restriction upregulates autophagy.
Not exact matches
«It appears the immune system becomes educated when there is an overlap of solids and breast milk because the milk promotes tolerogenic mechanisms against the solids.
We're just now starting to discover how taste receptors in the upper respiratory tract are used to regulate the immune system against these infections, so defining the underlying mechanisms at play is critical to understanding these illnesses and developing new treatments.»
According to the scientists» findings, targeting c - FLIP with the OH14 compound works on two fronts: first by helping to deactivate the tumour's self - defense mechanism against the immune system and second to prevent its regrowth.
To combat pathogens, the immune system has developed various mechanisms to detect, defend against and even destroy micro-organisms that are harmful to the body.
The immune activation from the CAR cells was also met with resistance mechanisms, including an upregulation of immunosuppressive pathways which may work against the patient and for the tumor, the researchers found.
«Surprisingly, the immune response directed against these bacteria helps the patient to better fight his / her tumor, by stimulating fresh immune defence mechanisms.»
An international research team led by Université de Montréal medical professor Christopher Rudd, director of research in immunology and cell therapy at Maisonneuve - Rosemont Hospital Research Centre, has identified a key new mechanism that regulates the ability of T - cells of the immune system to react against foreign antigens and cancer.
Medical professor Christopher Rudd and his research team have identified a key new mechanism that regulates the ability of T - cells of the immune system to react against foreign antigens and cancer.
The mechanism of action is based on the activation of macrophages to defend against tumors by direct tumor cytotoxicity and consequently they secrete cytokines which recruit secondary immune cells, presenting antigen to T cells [5 - 7].
Further, cellular defense mechanisms, such as the innate immune responses are mainly directed outwards to protect the organism against irritants, pathogens, or injured cells.
She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.
Her current work continues to focus on characterizing the mechanisms that enable immune responses against cancer.
Properly engineered immune cells could enable scientists to direct highly specific, long - lasting immune response mechanisms against a disease.
«The observed increase in the ratio of cytotoxic CD4 T cells to CD4 helper T cells indicates that they are an important component of the protective immune response to viral infections and that their induction should be an important marker for successful vaccinations against certain viral diseases,» says postdoctoral researcher and first author Veena Patil, Ph.D. «But we really didn't know enough about their molecular profile and the mechanisms that drive their differentiation and maintenance.»
The new mechanism of cooperation reported might be implicated in protection against asthma, allergies and immune - mediated diseases that has been associated with a carrier state,» said Raquel Hontecillas, associate professor of immunology, NIMML co-director, and corresponding author of the publication.
Increases levels of properdin, a chemical that activates part of the immune system responsible for increasing defence mechanisms against viral and bacterial attacks.
These are the defense mechanisms of your immune system and work to protect your body against viruses and bacteria that make you sick.
Zonulin evolved as an adaptive mechanism to flush out microorganisms as part of the innate immune response against bacterial colonization of the small intestine (Fasano, 2011).
They also hypothesize that antibiotics may increase breast cancer risk because they inhibit key parts of the immune system that protect against cancer, as well as anti-inflammatory mechanisms.
«Probiotics could theoretically even worsen a disease state, since it is possible that physiologic immune responses against benign commensals could fuel autoimmune responses via cross-reactivity (as we hypothesize) or other mechanisms,» he said.
Autophagy is the key intracellular immune mechanism that protects against bacterial and viral infections.
Because it takes some time for the immune system to respond correctly by elaborating own defense mechanism against the disease that your dog was vaccinated against.