Sentences with phrase «immune memory»

Such immune memory can fade with time, and sometimes quite rapidly, depending on the specific organism.

Some dogs never appear to mount an adequate antibody response to vaccination, but remain healthy, presumably because of persistence of immune memory cells and development of cell - mediated and mucosal immune responses, or alternatively, lack of exposure to infectious virus.

Measles is known to cause transient immunosuppression, but close inspection of the mortality data suggests that it disables immune memory for 2 to 3 years.

He and his colleagues have made significant discoveries about how immune memory cells are created and how long they survive; understanding these mechanisms is crucial to the development of vaccines for HIV and other infectious agents.

Because detection of ASCs in the blood provides an early correlate of subsequent immune memory in the gut mucosa, the researchers focused on these responses at multiple time points following BivWC vaccination in 24 healthy Haitian adults.

In a decades - long game of hide and seek, scientists from Sydney's Westmead Institute for Medical Research have confirmed for the very first time the specific immune memory T - cells where infectious HIV «hides» in the human body to evade detection by the immune system.

Current immunotherapy is based the reactivation of these T lymphocytes; however, little is known about how they can be generated more effectively, and in particular how immune memory can be triggered to prevent the development of tumors and metastasis.»

We used an immunization model of the perforin - deficient mouse to study the effects of immune memory on FHL2.

A second set of experiments, in which a second heart was grafted roughly a month after rejection to give potential immune memory more time to develop, showed similar long - term acceptance.

«Organ transplant rejection may not be permanent: Organ transplant rejection in previously tolerant hosts does not lead to permanent immune memory, mouse study shows.»

Some have even suggested that a typical immune memory function does not exist in the mucosa,» says Mats Bemark, associate professor of immunology at Sahlgrenska Academy, University of Gothenburg.

At these contact sites, the rapid immune memory response is literally «orchestrated,» say the researchers.

«It's really about finding different ways to develop better vaccines, ones that will harness the power of macrophages and finally put the body's innate immune memory to use» says Dr. Barreiro.

Preventing measles prevents immune memory damage and nonspecifically safeguards against many childhood infections.

By preventing measles - associated immune memory loss, vaccination protects polymicrobial herd immunity.

2014 February: Foxp3 + T cells inhibit antitumor immune memory modulated by mTOR inhibition.

The live attenuated vaccine primer created strong immune memory in both age groups, regardless of whether volunteers received one or two doses.

The combination of a CD4 antibody with an mTOR inhibitor may enhance immune memory and eradicate solid tumors.

«We predicted that exhausted T cells would not have a distinct epigenetic profile but have the molecular flexibility to obtain immune memory,» Wherry said.

(A) Serum TNF - α shows no difference in immune memory compared with control and this is unaffected by IFN - γ blockade.

These results suggest that pre-existing immune memory may worsen the outcome and alter the treatment response for FHL2 patients who may not be naive to their immune triggers.

The hallmark of an effective T cell response is the formation of a stable long - lived population of cells that mediate immune memory.

The response is specific to the microbe and leaves a lasting immune memory, which makes the response to future reinfection more efficient (see here for more information).

T cell activation, important for long term immune memory, requires 14 - hydroxy retro - retinol.

As most studies of FHL2 mice have used pathogen - naive animals, the effects of immune memory on FHL2 are understudied.

Associate Professor Palmer said that this next - generation test showed that HIV hides in the body's immune memory T - cells, which is how it avoids detection from the immune system.

«Our results change the paradigm that immune memory of a transplant rejection is invariably permanent.»

«How antiviral antibodies become part of immune memory: Survey of activated B cells during Ebola infection, flu vaccination in humans.»

When you're an adult, you have a population of T cells that give you your immune memory for lifetime.

During this process, the virus alters its appearance and our immune memory cells struggle to recognise it, leaving the virus free to infect us once more.

Expansion is unaffected by IFN - γ blockade (CD90, CD8, CD44, TNF - α); however, the effect of immune memory is significant by two - way ANOVA, * p < 0.05 (n = 3 — 4, two experimental replicates).

Effect of immune memory is significant by two - way ANOVA, * p < 0.05.

Expansion is unaffected by IFN - γ blockade (CD90, CD8, CD44, IFN - γ); however, the effect of immune memory is significant by two - way ANOVA, * p < 0.05.