Sentences with phrase «immune receptor genes»

Recent research has identified the innate immune receptor genes TREM2 and CD33 / SIGLEC3 as particularly relevant to Alzheimer's disease.

Not exact matches

One key gene encodes the making of a receptor called TREM2, a docking site for molecules on the surface of microglia and other innate immune cells.

The gene codes for an immune receptor on red blood cells; lack of that receptor prevents infection by Plasmodium vivax, a species of the malaria parasite.

Jarjour and his team studied a family of immune response genes called toll - like receptors (TLRs), which are responsible for sending out chemical «danger signals» when a bacteria or virus is detected.

In addition, they identified two variants in a second immune system gene, IL2RA, which codes for a protein called the IL - 2 receptor.

It binds to a type of receptor found in almost every cell in the body and can regulate the expression of genes that deal with immune response.

The researchers used the new technique to mutate the genes CXCR4 and CCR5, which encode receptor molecules that different strains of the HIV virus use to sneak in and infect immune cells and which have been targeted in previous cell therapy trials.

These genes typically encode immune receptors that recognize specific protein components of the fungal pathogen to trigger resistance.

CAR - T immunotherapy involves genetically outfitting a patient's immune cells with a new artificial gene, a chimeric antigen receptor (CAR), which allows the cells to recognize and attack specific cancer cells.

Specific canonical pathways enriched with such genes included PPAR signalling, cytokine signaling between immune cells and G - protein coupled receptor signalling (Table S2).