Signaling through innate
immune receptors promotes commensal bacteria colonization of the gut.
Not exact matches
In this study, the researchers found that a specific population of
immune cells called macrophages have the ability to secrete or produce a protective or healing factor known as Interleukin - 10 (IL - 10), which can interact with
receptors on intestinal epithelial cells to
promote wound healing.
Current thinking regarding type III hypersensitivity is that
immune cells within tissues sense the presence of these
immune complexes (ICs) through specific
receptor molecules and release inflammatory factors called cytokines that activate the endothelial cells lining adjacent blood vessels to
promote the recruitment of neutrophils.
Scientists have known that LPA is secreted by many types of cancer cells, appears to
promote the growth and spread of tumor cells, and that
immune cells known as CD - 8 «killer» T cells have several
receptors for LPA.
A significant amount of scientific data underlines that targeting the adenosine - cancer axis through the A2A
receptor can
promote anti-tumor
immune responses and lead to tumor regression.
The adenosine A2A
receptor is the main adenosine
receptor expressed on
immune cells, which
promotes immune suppression, leading to tumor evasion.
The adenosine A2A
receptor is the main adenosine
receptor expressed on
immune cells, which
promote anti-tumor
immune responses, leading to tumor regression when inhibited with an adenosine A2A antagonist.
Binding of adenosine to the A2A
receptor on
immune cells blocks the activation and effector functions of anti-tumor
immune cells and
promotes a regulatory,
immune - suppressive phenotype.
receptor is the main adenosine
receptor expressed on
immune cells, which
promotes immune suppression, leading to tumor evasion.
The adenosine A ₂ ₐ
receptor is the main adenosine
receptor expressed on
immune cell subsets including T - cells, NK cells and dendritic cells and binding of adenosine to the A ₂ ₐ
receptor on
immune cells blocks the activation and effector functions of anti-tumor
immune cells and
promotes a regulatory,
immune - suppressive phenotype.
So, now we know «specific dietary compounds present in cruciferous vegetables act through the Ah [
receptors] to
promote intestinal
immune function.»