The phrase
"immune reconstitution" refers to the process of rebuilding or strengthening the immune system after it has been weakened or compromised. It involves restoring the body's ability to fight off infections and diseases by boosting the production of immune cells and improving their function.
Full definition
Patients receiving abatacept had
intact immune reconstitution, significant improvement in transplantation - related mortality, no major uncontrolled infection and no increase in disease relapse.
While humanized mouse models for HIV infection have utility, the model is limited due to
incomplete immune reconstitution, development of xenogeneic graft versus host disease (GVHD), and the absence of normal T cell homeostasis.
Warren D. Shlomchik, M.D. Yale University Memory T cells for
improved immune reconstitution and GVL in allogeneic hematopoietic stem cell transplantation
Studies to improve the knowledge of genetic diseases include the natural history study for MLD, advanced diagnosis and natural history of primary immunodeficiencies and immunedysregulatory disorder, and
immune reconstitution after hematopoietic stem cell transplantation for genetic disorders.
Autologous hematopoietic stem cell transplantation (AHSCT) has been investigated as a treatment for aggressive MS, the rationale for which is
immune reconstitution.
The workshop will include research on stem cells and aging, implications of aging on immune function (immunosenescence,
immune reconstitution), thrombosis and aging, and correlates of frailty in hematology.