Sentences with phrase «immune repertoire»
The phrase "immune repertoire" refers to the collection of different immune cells and molecules found in a person's body that work together to protect them from diseases and infections. It includes various types of immune cells, such as T cells and B cells, as well as the diverse range of antigens or foreign substances that the immune system can recognize and fight against. The immune repertoire is essential for our body's defense mechanism and helps keep us healthy. Full definition
Collaborators all over the world participating in Han's project have sequenced over 5,000 individual immune repertoires from various diseases.
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One avenue of our translational research aims to determine the impact of in utero HIV - 1 exposure on infant immunity to vaccinations and co-infections by dissecting the infant immune repertoire present at birth in the context of maternal HIV - 1 infection and how the infant T cell repertoire changes following early life exposures compared to infants born to the HIV - 1 uninfected women of similar socio - economic status.
GigaGen focuses its activity on discovering new biological treatments by using antibodies derived from millions of cells within immune repertoires.
GigaGen's technology platform captures the genetic make - up of entire immune repertoires, genetically analyzing B cells at a rate of millions per hour, while simultaneously identifying their antigen and protein binders.
«We need to set the standards a little higher, consider the whole immune repertoire, the whole beauty of the immune system and what it can do.»
We are interested in evaluating the role of maternal viral load, immune activation and plasma cytokine environment on the neonatal immune repertoire present at birth by measuring cord blood TCR diversity through amplification of the CDR3 region followed by sequence analysis of expanded clones.
Current projects include quantitative models of the tumor microenvironment, the adaptive immune repertoire, and tumor evolution.
From a simple blood draw, the test reads the DNA of the patient's immune repertoire to find the immune cell barcodes associated with the cancer.
Staying Ahead of Disease Meanwhile, Seattle - based Adaptive Biotechnologies has already seen results in its immune repertoire sequencing.
A Disease Database Han is spearheading a project to sequence, or analyze, the immune repertoires of 10,000 people, representing 100 different diseases.
Diagnosing patients with vague symptoms would become much easier: Rather than try a litany of tests, the doctor would just look at the immune repertoire and find the matching disease.
To do this, Davis is sequencing the immune repertoires of individuals before, a week after and a month after receiving a vaccine.
The diversity of all the different barcodes in a person's body is called the immune repertoire.
«It takes a ridiculously large chunk of our immune repertoire to keep this virus in check,» Barry says.
GigaGen is a biopharmaceutical company that develops novel antibody therapies derived from immune repertoires.
Immunosequencing opens a new window of discovery, revealing the breadth and depth of the immune repertoire in exquisite molecular detail.
Thanks to decades of work by Dr. Steinman and other CRI investigators, it is now known that DCs are exceptionally powerful initiators of immunity, with the ability to activate an immune response up to 100 times more potent than any other cell in the immune repertoire.