Sentences with phrase «immune response against»

The researchers vaccinated mice with human embryonic stem cells and found that the mice developed a consistent immune response against colon cancer cells.
Abortive infections In some instances, a cat can mount an effective immune response against the virus and completely eliminate it, but these abortive infections are rare.
Also, cats mount a much more aggressive immune response against the worms than do dogs, and the resulting inflammation is responsible for much of the damage in the feline form of this disease.
Developing a vaccination has historically been fraught with difficulty simply because it is the immune response against the virus that causes the disease.
Adjuvant is a chemical, microbial constituent, or mammalian protein commonly added to an inactivated (killed) viral or bacterial vaccine to enhance the immune response against a selected pathogen.
FLORHAM PARK, N.J., Sept. 9, 2014 — Zoetis has partnered with the renowned Gluck Equine Research Center at the University of Kentucky to show that FLUVAC INNOVATOR ®, the first equine influenza virus (EIV) vaccine, can provide a demonstrated cross-reactive immune response against emerging EIV strains.
Their most recent study demonstrated an immune response against Richmond 07.1 Although Richmond 07 is not circulating in the United States, it might be a threat to horses with international exposure.
These diets have their protein (usually meat) source sliced on a molecular level into such small fragments that your pet's immune system can't recognize it or mount an immune response against it.
Vaclac Vetvicka, Jana Vetvickova, «Glucan supplementation enhances the immune response against an influenza challenge in mice,» Ann Transl Med, 2015 Feb; 3 (2): 22.
They stimulate the innate immune response against intracellular pathogens, helping to heal brain infections.
Zonulin evolved as an adaptive mechanism to flush out microorganisms as part of the innate immune response against bacterial colonization of the small intestine (Fasano, 2011).
As a physician with a special interest in intracellular infections I was very interested in the claim near the top that ketogenic diets «stimulate the innate immune response against intracellular pathogens, helping to heal brain infections.»
This lab allows us to see whether there is any abnormal immune response against many parts of the body.
It is Dr. Chou's hope that, by treating colon cancer stem cells with DAC and then exposing them to immune cells that have been primed to recognize NY - ESO - 1, he can generate a targeted and durable immune response against these cells without harming healthy cells.
G100 is designed to trigger a broad immune response against those newly - encountered antigens.
Also, CMB305 was well tolerated, and generated a strong and broad anti-NY-ESO-1 immune response in > 50 % of the patients, including evidence of antigen spreading — the induction of an immune response against other tumor antigens not targeted by CMB305.
«We have created a potentially much less expensive approach to making a therapeutic cancer vaccine that, while targeting a single tumor antigen, generates an immune response against multiple antigens.
February 9, 2011 Human and mouse studies sharpen focus on cause of celiac disease Blocking a factor that can activate the human immune response against intestinal bacteria or certain foods could prevent the development of celiac disease in those most at risk, researchers report in the journal Nature.
They can attack cancer cells directly, or they can be used to trigger an immune response against the tumor (so - called cancer immunotherapy).
The same year, the FDA approved the start of the first human clinical trial of this vaccine that demonstrated its safety and efficacy at inducing an immune response against the virus.
Providing apparently compelling evidence against the possibility of laboratory contamination, a number of the patients were shown to have mounted an immune response against XMRV.
We found that old animals bearing CD8 + TCE within Vbeta10 or Vbeta8 families failed to mount an effective immune response against HSV - 1, as judged by reduced numbers of peptide - major histocompatibility complex tetramer + CD8 T cells and an absence of antiviral lytic function.
There, they will be exposed to tumor antigens released from dying glioma cells through TK + valacyclovir - induced glioma cell death, and thus mediate a specific anti-malignant glioma immune response against remaining malignant glioma cells.
Publishing in The Lancet journal a group of researchers have analysed data from a previous outbreak of Zika virus in French Polynesia and report that of 42 patients diagnosed with Guillain - Barré syndrome at the time, all showed signs of an immune response against Zika whereas only half of those in a control group did.
Cancer vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens.
Therapeutic cancer vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.
Under the mentorship of Drs. Richard L. Hurwitz and Catherine M. Bollard, he characterized the immune response against an adenoviral vector delivered intravitreally in retinoblastoma patients.
Therapeutic vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.
The primary focus will be to work as a member of the team responsible for delineating the immune response against nairoviruses to aid effective vaccine design.
She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.
This includes utilizing a modified chimpanzee virus as a vaccine carrier to induce an immune response against HIV, and a new therapeutic vaccine against human papillomavirus (HPV), a leading cause of cervical cancer.
In different contexts, viruses appear capable of attacking tumors in a number of different ways — by directly infecting them, by releasing tumor proteins that trigger a broad immune response against the cancer, and by damaging the blood supply tumors need to survive.
A recently published paper showed that mice with colon cancer can be «vaccinated» with human embryonic stem cells and have a significant immune response against the cancer (Li et al., 2009).
While much recent research has not been published in this area, there is actually a long history of studies that show: (1) there is a significant number of antigens shared between tumors and embryonic tissues (called «oncofetal antigens») and, consequently, antibodies made against tumors can also recognize embryonic tissues, and vice versa; (2) pregnancy confers some immunity against cancer (accompanied by antibody production against oncofetal antigens), not only against its occurrence but also against its growth; (3) similar to pregnancy, an immune response against cancer can be generated by vaccinating animals with embryonic tissues.
Individuals who are infected with both HIV - 1 and HIV - 2 do better than those infected with HIV - 1 alone, suggesting that the immune response against HIV - 2 protects against the effects of HIV - 1 infection.
Cancer vaccines are designed to stimulate an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.
Role of CD4 + T cells in a protective immune response against Cryptococcus neoformans in the central nervous system.
Blocking a factor that can activate the human immune response against intestinal bacteria or certain foods could prevent the development of celiac disease in those most at risk, researchers report in the journal Nature.
TLR8 is found inside dendritic cells, which are patrolling immune cells that instigate, direct and fuel the immune response against infectious agents and malignant cells.
A paper published recently showed that the H3N2 vaccine strain with egg - based mutations was less able to mount an immune response against the circulating H3N2 strain.
Dr. Khleif's research interest is in identifying new and improved strategies to enhance specific immune response against cancer for preventive and therapeutic intent.
«If you immunize people with an antigen that induces an immune response against schistosomiasis, there will likely be benefits not only in controlling the immediate infection but also a means to avoid bladder cancer.»
Hu14.18 K332A is a laboratory - produced antibody designed to activate the immune response against tumor cells by recognizing and binding to an antigen found on the surface of most neuroblastoma tumor cells.
If melanoma cells can be made to produce IL - 2, this should stimulate a strong, specific immune response against them.
A T - cell marker panel that can identify subsets of tumor - associated T - cells allows scientists to identify and target subpopulations of T - cells playing unique roles in the immune response against a tumor.
Cancer vaccines, engineered to continue to train T cells to mount a strong immune response against your cancer, also haven't been very effective at mounting a strong fight, says He, and likely one weak point is the lack of strong receptors.
In experiments in animals, researchers from the University of Michigan Medical School showed that adding rapamycin to an immunotherapy approach strengthened the immune response against brain tumor cells.
Researchers at the University of Maryland and Duke University have designed a novel protein - sugar vaccine candidate that, in an animal model, stimulated an immune response against sugars that form a protective shield around HIV.
The animals had no detectable immune response against the eCD4 - Ig, presumably because it is so similar to pieces of their own cells.
These types of engineered tumors are much more difficult to treat than human tumors implanted in mice, because they suppress the immune response against them.
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