Sentences with phrase «immune response against the cancer cells»

«We're able to shuttle millions of cells through this device, generating a very potent immune response against the cancer cells,» Mooney says.

Not exact matches

It also boosts the body's immune response against infections and cancer cells and plays an important role in thyroid function and fertility.

And using cells from someone other than the cancer patient being treated might trigger an immune response against the foreign cells.

On its own, this immune response had no immediate effect in the fight against the utilized breast tumors, but in combination with the ADC it proved itself effective in attacking cancer cells in mice, resulting in the complete cure of the majority of mice receiving the combination therapy.

A recent study published in Cell revealed that, while the related parasite Tritrichomonas musculis makes the intestine susceptible to both colitis and colorectal cancer, it induces an immune response that protects mice against Salmonella infection.

«Dendritic cells are essential for prompting the immune response against malignant cells and for driving the clinical success of cancer immunotherapy, but their function is often defective in cancer patients,» said Dmitry I. Gabrilovich, M.D., Ph.D., Christopher M. Davis Professor and program leader of the Immunology, Microenvironment & Metastasis Program at Wistar.

Now, scientists have modified Salmonella bacteria to trigger a particularly powerful immune response against human cancer cells implanted in mice, shrinking the tumors and — for the first time — preventing them from metastasizing.

For patients, down the road Dr. Ohashi envisions a new era of combined therapies to simultaneously target and kill these suppressive cells while augmenting the immune response against cancer.

They used the gene - editing CRISPR / Cas9 technique to sift the genomes of melanoma cells for changes that made tumors resistant to being killed by immune T cells, which are the main actors in the immune system response against infections and cancer cells.

In 2008, he joined the group of Caetano Reis e Sousa at the Cancer Research UK (CRUK) London Research Institute and later joined the Francis Crick Institute, where he was awarded Marie Curie and EMBO long - term postdoctoral fellowships to investigate innate immune receptors and signaling pathways that trigger dendritic cell activation and drive T - cell responses against viruses or tumors.

Immunity is key to long - term responses Knowing that the immune system is capable of recognizing distinctive features of cancer cells and launching a T cell attack against those tumor antigens, and that checkpoint blockade removes a roadblock to that attack, it's logical that these drugs should work against many tumor types.

Cancer vaccines, engineered to continue to train T cells to mount a strong immune response against your cancer, also haven't been very effective at mounting a strong fight, says He, and likely one weak point is the lack of strong receCancer vaccines, engineered to continue to train T cells to mount a strong immune response against your cancer, also haven't been very effective at mounting a strong fight, says He, and likely one weak point is the lack of strong rececancer, also haven't been very effective at mounting a strong fight, says He, and likely one weak point is the lack of strong receptors.

Immuno - oncology, as the name implies, recruits the immune system into the battle against cancer, either by boosting its existing but latent anti-tumor responses or honing its recognition of malignant cells.

Cancer vaccines are designed to stimulate an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antCancer vaccines are designed to stimulate an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antcancer cells bearing these antigens.

A recently published paper showed that mice with colon cancer can be «vaccinated» with human embryonic stem cells and have a significant immune response against the cancer (Li et al., 2009).

She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.

Therapeutic vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

Therapeutic cancer vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

They can attack cancer cells directly, or they can be used to trigger an immune response against the tumor (so - called cancer immunotherapy).

It is Dr. Chou's hope that, by treating colon cancer stem cells with DAC and then exposing them to immune cells that have been primed to recognize NY - ESO - 1, he can generate a targeted and durable immune response against these cells without harming healthy cells.

A pilot study demonstrated this combination elicited a powerful, targeted immune response directed against osteosarcoma cells in patients suffering from this type of cancer.

It is a cancer of lymphocytes, which are small white blood cells that play a role in the body's immune response in the fight against germs and diseases.

The researchers vaccinated mice with human embryonic stem cells and found that the mice developed a consistent immune response against colon cancer cells.